Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $2,250.0 million
Deal Type : Licensing Agreement
Monte Rosa, Novartis Close Deal on VAV1 Molecular Glue for T And B Cell Modulation
Details : Under the licensing agreement, Novartis will gain exclusive global rights to develop, manufacture, and commercialize MRT-6160, currently under study for immune-mediated conditions.
Product Name : MRT-6160
Product Type : Small molecule
Upfront Cash : $150.0 million
December 11, 2024
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $2,250.0 million
Deal Type : Licensing Agreement
Lead Product(s) : MRT-2359
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Monte Rosa Updates MRT-2359 Phase 1/2 Study Progress for MYC-driven Tumors
Details : MRT-2359 is a potent, highly selective, and orally bioavailable investigational molecular glue degrader. Currently,It is being evaluated for the treatment of MYC-driven solid tumors.
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Not Applicable
December 05, 2024
Lead Product(s) : MRT-2359
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $2,250.0 million
Deal Type : Licensing Agreement
Monte Rosa Licenses VAV1 Molecular Glue Degraders to Novartis
Details : Under the licensing agreement, Novartis will gain exclusive global rights to develop, manufacture, and commercialize MRT-6160, currently under study for immune-mediated conditions.
Product Name : MRT-6160
Product Type : Small molecule
Upfront Cash : $150.0 million
October 28, 2024
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $2,250.0 million
Deal Type : Licensing Agreement
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Monte Rosa Therapeutics Announces First Participants Dosed in MRT-6160 Phase 1 Study
Details : MRT-6160 is an orally bioavailable VAV1 degrader, which is being developed for the treatment of eurological autoimmune diseases.
Product Name : MRT-6160
Product Type : Small molecule
Upfront Cash : Not Applicable
August 19, 2024
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : MRT-2359
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Monte Rosa Therapeutics Provides Development Progress Updates on MRT-2359 and MRT-6160
Details : MRT-2359 is a potent, highly selective, and orally bioavailable investigational molecular glue degrader. Currently,It is being evaluated for the treatment of MYC-driven solid tumors.
Product Name : MRT-2359
Product Type : Small molecule
Upfront Cash : Not Applicable
June 27, 2024
Lead Product(s) : MRT-2359
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : TD Cowen
Deal Size : $100.0 million
Deal Type : Public Offering
Monte Rosa Therapeutics Announces Pricing of $100 Million Underwritten Public Offering
Details : The proceeds will fund the development of MRT-6160, an orally bioavailable VAV1 degrader, MRT-8102, as well the utilization of the QuEENTM platform to develop immunology and inflammation targets.
Product Name : MRT-6160
Product Type : Small molecule
Upfront Cash : Undisclosed
May 16, 2024
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : TD Cowen
Deal Size : $100.0 million
Deal Type : Public Offering
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Study Phase : IND Enabling
Sponsor : TD Cowen
Deal Size : Undisclosed
Deal Type : Public Offering
Monte Rosa Therapeutics Proposes Public Offering of Common Stock and Pre-Funded Warrants
Details : The proceeds will fund the development of MRT-6160, an orally bioavailable VAV1 degrader, MRT-8102, as well the utilization of the QuEENTM platform to develop immunology and inflammation targets.
Product Name : MRT-6160
Product Type : Small molecule
Upfront Cash : Undisclosed
May 15, 2024
Lead Product(s) : MRT-6160
Therapeutic Area : Immunology
Highest Development Status : IND Enabling
Sponsor : TD Cowen
Deal Size : Undisclosed
Deal Type : Public Offering
Lead Product(s) : MRT-8102
Therapeutic Area : Rheumatology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Monte Rosa Begins IND Studies for MRT-8102, a NEK7 Directed Degrader
Details : MRT-8102 is a first-in-class NEK7-directed molecular glue degrader and NLRP3/IL-1β pathway inhibitor being evaluated for multiple inflammatory diseases, including gout and pericarditis.
Product Name : MRT-8102
Product Type : Small molecule
Upfront Cash : Not Applicable
March 11, 2024
Lead Product(s) : MRT-8102
Therapeutic Area : Rheumatology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : MRT-2359
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : $25.0 million
Deal Type : Public Offering
Details : Monte Rosa intends to use the proceeds towards the advancement of its clinical and late preclinical pipeline, including MRT-2359, its orally bioavailable, GSPT1-directed MGD, MRT-6160, its orally bioavailable VAV1-directed MGD, and its NEK7 program.
Product Name : MRT-2359
Product Type : Small molecule
Upfront Cash : Undisclosed
October 26, 2023
Lead Product(s) : MRT-2359
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : $25.0 million
Deal Type : Public Offering
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery
Sponsor : F. Hoffmann-La Roche
Deal Size : $2,050.0 million
Deal Type : Licensing Agreement
Details : The collaboration aims to discover and develop MGDs, small molecule protein degraders, against targets in cancer and neurological diseases previously considered impossible to drug by using Monte Rosa Therapeutics’ highly differentiated QuEENTM discover...
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : $50.0 million
October 17, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery
Sponsor : F. Hoffmann-La Roche
Deal Size : $2,050.0 million
Deal Type : Licensing Agreement