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    [{"orgOrder":0,"company":"Monte Rosa Therapeutics","sponsor":"TD Cowen","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Public Offering","leadProduct":"MRT-6160","moa":"VAV1","graph1":"Immunology","graph2":"Phase I","graph3":"Monte Rosa Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Monte Rosa Therapeutics \/ TD Cowen","highestDevelopmentStatusID":"6","companyTruncated":"Monte Rosa Therapeutics \/ TD Cowen"},{"orgOrder":0,"company":"Monte Rosa Therapeutics","sponsor":"TD Cowen","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Public Offering","leadProduct":"MRT-6160","moa":"VAV1","graph1":"Immunology","graph2":"Phase I","graph3":"Monte Rosa Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph 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Therapeutics","sponsor":"Cancer Research Uk","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"MRT-048","moa":"GSPT1 protein","graph1":"Oncology","graph2":"Preclinical","graph3":"Monte Rosa Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Monte Rosa Therapeutics \/ Cancer Research Uk","highestDevelopmentStatusID":"4","companyTruncated":"Monte Rosa Therapeutics \/ Cancer Research Uk"},{"orgOrder":0,"company":"Monte Rosa Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"MRT-048","moa":"GSPT1 protein","graph1":"Oncology","graph2":"Preclinical","graph3":"Monte Rosa Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Monte Rosa Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Monte Rosa Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Monte Rosa Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Public Offering","leadProduct":"MRT-2359","moa":"GSPT1 protein","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Monte Rosa Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Monte Rosa Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Monte Rosa Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Monte Rosa Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"MRT-2359","moa":"GSPT1 protein","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Monte Rosa Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Monte Rosa Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Monte Rosa Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Monte Rosa Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"MRT-8102","moa":"Undisclosed","graph1":"Rheumatology","graph2":"IND Enabling","graph3":"Monte Rosa Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Monte Rosa Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Monte Rosa Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Monte Rosa Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"MRT-2359","moa":"GSPT1 protein","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Monte Rosa Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Monte Rosa Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Monte Rosa Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Monte Rosa 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Hoffmann-La Roche","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Licensing Agreement","leadProduct":"Undisclosed","moa":"Molecular glue","graph1":"Oncology","graph2":"Preclinical","graph3":"Monte Rosa Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Monte Rosa Therapeutics \/ F. Hoffmann-La Roche","highestDevelopmentStatusID":"4","companyTruncated":"Monte Rosa Therapeutics \/ F. Hoffmann-La Roche"},{"orgOrder":0,"company":"Monte Rosa Therapeutics","sponsor":"Avoro Capital","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Series C Financing","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Oncology","graph2":"Preclinical","graph3":"Monte Rosa Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Monte Rosa Therapeutics \/ Avoro Capital","highestDevelopmentStatusID":"4","companyTruncated":"Monte Rosa Therapeutics \/ Avoro Capital"},{"orgOrder":0,"company":"Monte Rosa Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"MRT-2359","moa":"GSPT1 protein","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Monte Rosa Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Monte Rosa Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Monte Rosa Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Monte Rosa Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"MRT-2359","moa":"GSPT1 protein","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Monte Rosa Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Monte Rosa Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Monte Rosa Therapeutics \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals by Monte Rosa Therapeutics

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                            01

                            Monte Rosa Therapeutics

                            U.S.A arrow
                            German Wound Congress
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                            Monte Rosa Therapeutics

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                            Lead Product(s) : MRT-2359

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Monte Rosa Updates MRT-2359 Phase 1/2 Study Progress for MYC-driven Tumors

                            Details : MRT-2359 is a potent, highly selective, and orally bioavailable investigational molecular glue degrader. Currently,It is being evaluated for the treatment of MYC-driven solid tumors.

                            Product Name : MRT-2359

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 05, 2024

                            Lead Product(s) : MRT-2359

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Monte Rosa Therapeutics

                            U.S.A arrow
                            German Wound Congress
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                            Monte Rosa Therapeutics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $2,250.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Monte Rosa, Novartis Close Deal on VAV1 Molecular Glue for T And B Cell Modulation

                            Details : Under the licensing agreement, Novartis will gain exclusive global rights to develop, manufacture, and commercialize MRT-6160, currently under study for immune-mediated conditions.

                            Product Name : MRT-6160

                            Product Type : Other Small Molecule

                            Upfront Cash : $150.0 million

                            November 12, 2024

                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $2,250.0 million

                            Deal Type : Licensing Agreement

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                            03

                            Monte Rosa Therapeutics

                            U.S.A arrow
                            German Wound Congress
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                            Monte Rosa Therapeutics

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                            German Wound Congress
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                            Lead Product(s) : MRT-8102

                            Therapeutic Area : Rheumatology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Monte Rosa Begins IND Studies for MRT-8102, a NEK7 Directed Degrader

                            Details : MRT-8102 is a first-in-class NEK7-directed molecular glue degrader and NLRP3/IL-1β pathway inhibitor being evaluated for multiple inflammatory diseases, including gout and pericarditis.

                            Product Name : MRT-8102

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 03, 2024

                            Lead Product(s) : MRT-8102

                            Therapeutic Area : Rheumatology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Monte Rosa Therapeutics

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                            German Wound Congress
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                            Monte Rosa Therapeutics

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                            German Wound Congress
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                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $2,250.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Monte Rosa Licenses VAV1 Molecular Glue Degraders to Novartis

                            Details : Under the licensing agreement, Novartis will gain exclusive global rights to develop, manufacture, and commercialize MRT-6160, currently under study for immune-mediated conditions.

                            Product Name : MRT-6160

                            Product Type : Other Small Molecule

                            Upfront Cash : $150.0 million

                            October 28, 2024

                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : $2,250.0 million

                            Deal Type : Licensing Agreement

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                            05

                            Monte Rosa Therapeutics

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                            German Wound Congress
                            Not Confirmed

                            Monte Rosa Therapeutics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Monte Rosa Therapeutics Announces First Participants Dosed in MRT-6160 Phase 1 Study

                            Details : MRT-6160 is an orally bioavailable VAV1 degrader, which is being developed for the treatment of eurological autoimmune diseases.

                            Product Name : MRT-6160

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 19, 2024

                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Monte Rosa Therapeutics

                            U.S.A arrow
                            German Wound Congress
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                            Monte Rosa Therapeutics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : MRT-2359

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Monte Rosa Therapeutics Provides Development Progress Updates on MRT-2359 and MRT-6160

                            Details : MRT-2359 is a potent, highly selective, and orally bioavailable investigational molecular glue degrader. Currently,It is being evaluated for the treatment of MYC-driven solid tumors.

                            Product Name : MRT-2359

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 27, 2024

                            Lead Product(s) : MRT-2359

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Monte Rosa Therapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            Monte Rosa Therapeutics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Study Phase : IND Enabling

                            Sponsor : TD Cowen

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Monte Rosa Therapeutics Announces Pricing of $100 Million Underwritten Public Offering

                            Details : The proceeds will fund the development of MRT-6160, an orally bioavailable VAV1 degrader, MRT-8102, as well the utilization of the QuEENTM platform to develop immunology and inflammation targets.

                            Product Name : MRT-6160

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            May 16, 2024

                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Highest Development Status : IND Enabling

                            Sponsor : TD Cowen

                            Deal Size : $100.0 million

                            Deal Type : Public Offering

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                            08

                            Monte Rosa Therapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            Monte Rosa Therapeutics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Study Phase : IND Enabling

                            Sponsor : TD Cowen

                            Deal Size : Undisclosed

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Monte Rosa Therapeutics Proposes Public Offering of Common Stock and Pre-Funded Warrants

                            Details : The proceeds will fund the development of MRT-6160, an orally bioavailable VAV1 degrader, MRT-8102, as well the utilization of the QuEENTM platform to develop immunology and inflammation targets.

                            Product Name : MRT-6160

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            May 15, 2024

                            Lead Product(s) : MRT-6160

                            Therapeutic Area : Immunology

                            Highest Development Status : IND Enabling

                            Sponsor : TD Cowen

                            Deal Size : Undisclosed

                            Deal Type : Public Offering

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                            09

                            Monte Rosa Therapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            Monte Rosa Therapeutics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : MRT-2359

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : $25.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Monte Rosa Therapeutics Announces $25 Million Registered Direct Offering, Priced at- the-Market Under Nasdaq R...

                            Details : Monte Rosa intends to use the proceeds towards the advancement of its clinical and late preclinical pipeline, including MRT-2359, its orally bioavailable, GSPT1-directed MGD, MRT-6160, its orally bioavailable VAV1-directed MGD, and its NEK7 program.

                            Product Name : MRT-2359

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            October 26, 2023

                            Lead Product(s) : MRT-2359

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : $25.0 million

                            Deal Type : Public Offering

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                            10

                            Monte Rosa Therapeutics

                            U.S.A arrow
                            German Wound Congress
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                            Monte Rosa Therapeutics

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                            German Wound Congress
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                            Lead Product(s) : MRT-2359

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Monte Rosa Therapeutics Announces Interim PK/PD and Clinical Data for MRT-2359 in Phase 1/2 Trial for MYC-Driv...

                            Details : MRT-2359 is a orally bioavailable investigational molecular glue degrader (MGD) that induces the interaction between the E3 ubiquitin ligase component cereblon and the translation termination factor GSPT1, leading to the targeted degradation of GSPT1 pro...

                            Product Name : MRT-2359

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 17, 2023

                            Lead Product(s) : MRT-2359

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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