Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
IntelGenx Reports Preliminary Results for Montelukast VersaFilm® in Alzheimer’s Disease
Details : Montelukast VersaFilm (montelukast) is a small molecule CysLT1 receptor inhibitor, given in the form of buccal film, is currently being ivestigated for patients with alzheimer's disease.
Brand Name : Montelukast VersaFilm
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 03, 2024
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
IntelGenx Doses First Parkinson’s Patients with Montelukast VersaFilm in Phase 2 Trial
Details : Montelukast VersaFilm (montelukast) is a leukotriene receptor antagonist, which is being evaluated in patients with Parkinson’s Disease, the second most common neurodegenerative disease.
Brand Name : Montelukast VersaFilm
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 08, 2024
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : VersaFilm® (montelukast) is a leukotriene receptor antagonist, which is completed patient enrollment in the ongoing Phase 2a clinical trial in patients with mild to moderate Alzheimer’s Disease.
Brand Name : Montelukast VersaFilm
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 14, 2023
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Study Phase : Approved
Sponsor : Tilray
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : The agreement aims for the co-development and commercialization of cannabinoid-infused VersaFilm® products, including CBD VersaFilm (cannabinoid), a unique drug opportunity for the treatment of neurodegenerative diseases of the brain.
Brand Name : CBD VersaFilm
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 06, 2023
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Highest Development Status : Approved
Sponsor : Tilray
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : VersaFilm® (montelukast) is a leukotriene receptor antagonist, which is completed patient enrollment in the ongoing Phase 2a clinical trial in patients with mild to moderate Alzheimer’s Disease.
Brand Name : Montelukast VersaFilm
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 01, 2023
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Study Phase : IND Enabling
Sponsor : Karolinska University Hospital
Deal Size : $2.0 million
Deal Type : Agreement
Details : The agreement aims to investigate the use of IntelGenx’s Montelukast VersaFilm, a leukotriene receptor antagonist, for the treatment of Parkinson’s Disease.
Brand Name : Montelukast VersaFilm
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 25, 2023
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Highest Development Status : IND Enabling
Sponsor : Karolinska University Hospital
Deal Size : $2.0 million
Deal Type : Agreement
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Karolinska Institute
Deal Size : $2.0 million
Deal Type : Collaboration
Details : Upon completion of the Study, IntelGenx will retain the intellectual property rights and use the findings to further develop its Montelukast VersaFilm® program for Parkinson's disease treatment.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 09, 2023
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Karolinska Institute
Deal Size : $2.0 million
Deal Type : Collaboration
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Resumption of patient dosing in the ongoing Phase 2a (BUENA) clinical trial of Montelukast VersaFilm, a leukotriene receptor antagonist on the basis of Phase 1 study data that reduces the first-pass-effect and has a 52% higher bioavailability.
Brand Name : Montelukast-Generic
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 20, 2022
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In Phase 1 studies, an oral film formulation of Montelukast is safe and tolerable in healthy subjects, reduces the first-pass-effect and has a 52% higher bioavailability compared to the Montelukast tablet, demonstrating a clear advantage of delivering Mo...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 12, 2021
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
IntelGenx Announces Publication of a Study Evaluating Montelukast’s Effect on Neurological Aging
Details : Data suggest Montelukast may inhibit mental decline, higher doses optimal for clinical trials assessing impact on neurological disease.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 09, 2020
Lead Product(s) : Montelukast Sodium
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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