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    [{"orgOrder":0,"company":"Morphic Therapeutic","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"MORF-057","moa":"Integrin alpha-4\/beta-7","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Morphic Therapeutic","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Morphic Therapeutic \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Morphic Therapeutic \/ Not Applicable"},{"orgOrder":0,"company":"Morphic Therapeutic","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"MORF-057","moa":"Integrin alpha-4\/beta-7","graph1":"Gastroenterology","graph2":"Phase II","graph3":"Morphic 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    Find Clinical Drug Pipeline Developments & Deals by Morphic Therapeutic

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                            01

                            Morphic Therapeutic

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                            Morphic Therapeutic

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                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Eli Lilly

                            Deal Size : $3,200.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Lilly Completes Acquisition of Morphic to Improve Outcomes for Inflammatory Bowel Disease

                            Details : The acquisition expands Lilly's immunology pipeline with MORF-057, a selective oral small molecule inhibitor of α4β7 integrin for the treatment of inflammatory bowel disease (IBD).

                            Brand Name : MORF-057

                            Molecule Type : Small molecule

                            Upfront Cash : $3,200.0 million

                            August 16, 2024

                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Eli Lilly

                            Deal Size : $3,200.0 million

                            Deal Type : Acquisition

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                            02

                            Morphic Therapeutic

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                            Morphic Therapeutic

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                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Eli Lilly

                            Deal Size : $3,200.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Lilly to Acquire Morphic to Improve Outcomes for Patients with Inflammatory Bowel Disease

                            Details : The acquisition expands Lilly's immunology pipeline with MORF-057, a selective oral small molecule inhibitor of α4β7 integrin for the treatment of inflammatory bowel disease (IBD).

                            Brand Name : MORF-057

                            Molecule Type : Small molecule

                            Upfront Cash : $3,200.0 million

                            July 08, 2024

                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Eli Lilly

                            Deal Size : $3,200.0 million

                            Deal Type : Acquisition

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                            03

                            Morphic Therapeutic

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                            Morphic Therapeutic

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                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Jefferies

                            Deal Size : $276.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Morphic Therapeutic Announces Closing of Public Offering and Full Exercise of Underwriters™ Option to Purcha...

                            Details : The net proceeds will be used to fund research, clinical trials and process development and manufacturing of company's product candidates, including MORF-057, an oral small molecule inhibitor of the alpha4beta7 integrin and other programs generated from ...

                            Brand Name : MORF-057

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            May 05, 2023

                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Jefferies

                            Deal Size : $276.0 million

                            Deal Type : Public Offering

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                            04

                            Morphic Therapeutic

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                            Morphic Therapeutic

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                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Jefferies

                            Deal Size : $240.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Morphic Therapeutic Announces Pricing of $240.0 Million Public Offering

                            Details : The proceeds will fund research, clinical trial and process development of Morphic’s candidates, including MORF-057, a selective, oral small molecule inhibitor of the α4β7 integrin in development to treat IBD, and other programs generated from Morphi...

                            Brand Name : MORF-057

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            May 03, 2023

                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Jefferies

                            Deal Size : $240.0 million

                            Deal Type : Public Offering

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                            05

                            Morphic Therapeutic

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                            Morphic Therapeutic

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                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Morphic Reports Positive Topline Results of the EMERALD-1 UC Main Cohort; Orally Administered MORF-057 Achieve...

                            Details : MORF-057 is an oral small molecule inhibitor of the α4β7 integrin, which is being investigated in adults with moderate to severe ulcerative colitis (UC).

                            Brand Name : MORF-057

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 25, 2023

                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Morphic Therapeutic

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                            Morphic Therapeutic

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                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Morphic Announces Initiation of EMERALD-2 Phase 2b Clinical Trial of MORF-057 in Patients with Moderate-to-Sev...

                            Details : Morphic is developing MORF-057 as a selective, oral small molecule inhibitor of the α4β7 integrin for patients with inflammatory bowel disease. MORF-057, like vedolizumab, is designed to block the interactions between α4β7 on the surface of lymphocyt...

                            Brand Name : MORF-057

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 22, 2022

                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Morphic Therapeutic

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                            Morphic Therapeutic

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                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Morphic Presents New Positive MORF-057 Phase 1 Data at American College of Gastroenterology Annual Meeting 202...

                            Details : MORF-057 is a selective, oral small molecule, designed to block the interactions between α4β7 on the surface of lymphocytes and the mucosal endothelial cell ligand MAdCAM-1, substantially reducing lymphocyte migration from the bloodstream into intestin...

                            Brand Name : MORF-057

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 25, 2022

                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Morphic Therapeutic

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                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Morphic Announces Complete Enrollment of EMERALD-1 Main Cohort Ahead of Projections

                            Details : MORF-057 as a selective, oral small molecule inhibitor of the α4β7 integrin for patients with inflammatory bowel disease. α4β7 has been clinically validated as a target for the treatment of IBD by the success of the approved injectable antibody thera...

                            Brand Name : MORF-057

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 24, 2022

                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Morphic Therapeutic

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                            Morphic Therapeutic

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                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Morphic Presents New Positive MORF-057 Phase 1 Data at UEG Week 2022

                            Details : MORF-057 is selective, oral small molecule inhibitor of α4β7 integrin for patients with IBD, 200 mg BID dose demonstrates receptor saturation and statistically significant increases in key circulating T lymphocyte populations.

                            Brand Name : MORF-057

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 10, 2022

                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Morphic Therapeutic

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                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Morphic Therapeutic Announces Initiation of EMERALD-1 Phase 2a Clinical Trial of MORF-057 in Patients with Ulc...

                            Details : MORF-057 is a potent and selective, oral small molecule inhibitor of the α4β7 integrin being studied in patients with GI disorders, holds potential for treating inflammatory bowel diseases.

                            Brand Name : MORF-057

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 25, 2022

                            Lead Product(s) : MORF-057

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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