Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Pelabresib,Ruxolitinib Phosphate
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Acquisition
Novartis Meets All Tender Offer Conditions to Acquire MorphoSys for EUR 68 per Share
Details : Novartis will begin to progress the integration of MorphoSys, including full access to CPI-0610 (pelabresib), a novel BET inhibitor in combination with ruxolitinib for patients with myelofibrosis.
Product Name : CPI-0610
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
May 16, 2024
Lead Product(s) : Pelabresib,Ruxolitinib Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : Tafasitamab
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Incyte Corporation
Deal Size : $25.0 million
Deal Type : Agreement
Incyte Gains Exclusive Global Rights for Tafasitamab (Monjuvi®) Development
Details : Under the agreement, Incyte gains exclusive global rights for tafasiatamab, a humanized CD19-targeting immunotherapy marketed in the U.S. as Monjuvi.
Product Name : Monjuvi
Product Type : Antibody
Upfront Cash : Undisclosed
May 02, 2024
Lead Product(s) : Tafasitamab
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Incyte Corporation
Deal Size : $25.0 million
Deal Type : Agreement
Lead Product(s) : Pelabresib,Ruxolitinib Phosphate
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $2,897.9 million
Deal Type : Acquisition
Novartis Acquires MorphoSys AG To Strengthen Oncology Pipeline
Details : Novartis aims to enhance its oncology pipeline with CPI-0610 (pelabresib), a novel treatment for myelofibrosis with a favorable safety profile when combined with ruxolitinib.
Product Name : CPI-0610
Product Type : Other Small Molecule
Upfront Cash : $2,897.9 million
May 02, 2024
Lead Product(s) : Pelabresib,Ruxolitinib Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : $2,897.9 million
Deal Type : Acquisition
Lead Product(s) : Tulmimetostat,Carboplatin
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
MorphoSys Receives U.S. FDA Fast Track Designation for Tulmimetostat in Endometrial Cancer
Details : CPI-0209 (tulmimetostat) is an investigational compound designed to exert anti-tumor activity by inhibiting the EZH2 and EZH1, which is investigated for the treatment of endometrial cancer.
Product Name : CPI-0209
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 09, 2023
Lead Product(s) : Tulmimetostat,Carboplatin
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pelabresib,Ruxolitinib Phosphate
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CPI-0610 (pelabresib monohydrate) is an investigational BET inhibitor. It is being developed in combination with the JAK inhibitor ruxolitinib for the treatment of myelofibrosis.
Product Name : CPI-0610
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 20, 2023
Lead Product(s) : Pelabresib,Ruxolitinib Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tafasitamab,Lenalidomide
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Monjuvi (tafasitamab-cxix), is a humanized Fc-modified CD19 targeting immunotherapy. In 2010, MorphoSys licensed exclusive worldwide rights to develop and commercialize tafasitamab.
Product Name : Monjuvi
Product Type : Antibody
Upfront Cash : Inapplicable
December 05, 2022
Lead Product(s) : Tafasitamab,Lenalidomide
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : RO4909832 (gantenerumab) is fully-human mAB, studies did not meet their primary endpoint of slowing clinical decline. The level of beta-amyloid removal, the protein that builds up to make plaques in the brains of people with Alzheimer's disease.
Product Name : RO4909832
Product Type : Antibody
Upfront Cash : Inapplicable
November 14, 2022
Lead Product(s) : Otilimab,Methotrexate,Sulfasalazine
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : GSK3196165 (otilimab) is an investigational human monoclonal antibody directed against GM-CSF (granulocyte-macrophage colony-stimulating factor) that is developed by GSK for the treatment of rheumatoid arthritis.
Product Name : GSK3196165
Product Type : Antibody
Upfront Cash : Inapplicable
October 27, 2022
Lead Product(s) : Otilimab,Methotrexate,Sulfasalazine
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tulmimetostat
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : CPI-0209 (tulmimetostat) is an oral, investigational next-generation selective dual inhibitor of EZH2 and EZH1 designed to improve on first generation EZH2 inhibitors via increased potency, longer residence time on target and a longer half-life.
Product Name : CPI-0209
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 27, 2022
Lead Product(s) : Tulmimetostat
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Pelabresib,Ruxolitinib Phosphate
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Pelabresib (CPI-0610) is an investigational selective small molecule designed to promote anti-tumor activity by inhibiting the function of bromodomain and extra-terminal domain proteins to decrease the expression of abnormally expressed genes in cancer.
Product Name : CPI-0610
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 06, 2022
Lead Product(s) : Pelabresib,Ruxolitinib Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable