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II","therapeuticAreaShortName":"Musculoskeletal","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"AEON Biopharma \/ Priveterra Acquisition Corp.","highestDevelopmentStatusID":"8","companyTruncated":"AEON Biopharma \/ Priveterra Acquisition Corp."},{"orgOrder":0,"company":"AEON Biopharma","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Musculoskeletal","country":"U.S.A","productType":"Protein","year":"2022","type":"Financing","leadProduct":"Prabotulinumtoxin A","moa":"ACh receptor","graph1":"Musculoskeletal","graph2":"Phase II","graph3":"AEON Biopharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Musculoskeletal","amount2New":0,"dosageForm":"Intramuscular Injection","sponsorNew":"AEON Biopharma \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"AEON Biopharma \/ Undisclosed"}]

    Find Musculoskeletal Drugs in Phase II Clinical Development

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                            01

                            Antibe Therapeutics

                            Canada arrow
                            German Wound Congress
                            Not Confirmed

                            Antibe Therapeutics

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                            German Wound Congress
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                            • fda
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                            Lead Product(s) : Otenaproxesul

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Taro Pharmaceutical Industries

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Sun Pharma Subsidiary Taro Acquires Antibe Therapeutics

                            Details : Through the acquisition, Taro will leverage Antibe pipeline, including ATB-346 (otenaproxesul), a novel NSAID. It is being evaluated for the treatment of Osteoarthritis.

                            Product Name : ATB-346

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            January 16, 2025

                            Lead Product(s) : Otenaproxesul

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Taro Pharmaceutical Industries

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            02

                            TNF Pharmaceuticals

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            TNF Pharmaceuticals

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            TNF Pharmaceuticals Announces Positive Clinical Data Supporting Clinical Trial Expansion

                            Details : MYMD-1 (isomyosamine) is a TNF-alpha inhibitor drug, currently being investigated in patients with sarcopenia/frailty.

                            Product Name : MYMD-1

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 15, 2025

                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            AEON Biopharma

                            U.S.A arrow
                            German Wound Congress
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                            AEON Biopharma

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Prabotulinumtoxin A

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Aegis Capital

                            Deal Size : $20.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            AEON Biopharma, Inc. Announces Closing of $20.0 Million Underwritten Public Offering

                            Details : The net proceeds will be used to advance the clinical development of company's lead product ABP-450 (Prabotulinumtoxin A). It is being evaluated for the treatment of Cervical dystonia.

                            Product Name : ABP-450

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            January 07, 2025

                            Lead Product(s) : Prabotulinumtoxin A

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Aegis Capital

                            Deal Size : $20.0 million

                            Deal Type : Public Offering

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                            04

                            AEON Biopharma

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            AEON Biopharma

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Prabotulinumtoxin A

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Aegis Capital

                            Deal Size : $20.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            AEON Biopharma Announces $20M Underwritten Public Offering Pricing

                            Details : The net proceeds will be used to advance the clinical development of company's lead product ABP-450 (Prabotulinumtoxin A). It is being evaluated for the treatment of Cervical dystonia.

                            Product Name : ABP-450

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            January 06, 2025

                            Lead Product(s) : Prabotulinumtoxin A

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Aegis Capital

                            Deal Size : $20.0 million

                            Deal Type : Public Offering

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                            05

                            TNF Pharmaceuticals

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            TNF Pharmaceuticals

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Renova Health

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            TNF Pharmaceuticals Explores Sarcopenia Therapy Linked to GLP-1 Weight Loss Drugs

                            Details : Under the agreement, TNF will advance the MYMD-1 (isomyosamine) a TNF-α inhibitor. It is being evaluated in mid-stage studies for the treatment of Sarcopenia and frailty.

                            Product Name : MYMD-1

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            December 19, 2024

                            Lead Product(s) : Isomyosamine

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Renova Health

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            06

                            Lipocine

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            Lipocine

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Testosterone

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Grants Fast Track Designation to Lipocine for LPCN 1148 in Sarcopenia Treatment

                            Details : LPCN 1148 comprises testosterone dodecanoate, a unique androgen receptor agonist. It is being investigated for treatment for sarcopenia in patients with decompensated cirrhosis.

                            Product Name : LPCN 1148

                            Product Type : Steroid

                            Upfront Cash : Inapplicable

                            December 17, 2024

                            Lead Product(s) : Testosterone

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Angitia Biopharmaceuticals

                            China arrow
                            German Wound Congress
                            Not Confirmed

                            Angitia Biopharmaceuticals

                            China arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : AGA2118

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Bain Capital Life Sciences

                            Deal Size : $120.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Angitia Biopharmaceuticals Announces $120 Million Series C Financing

                            Details : The financing will enable Angitia to advance AGA2118 & AGA2115, bispecific antibodies targeting sclerostin and DKK1, through clinical development for the treatment of osteoporosis & OI, respectively.

                            Product Name : AGA2118

                            Product Type : Other Large Molecule

                            Upfront Cash : Undisclosed

                            December 11, 2024

                            Lead Product(s) : AGA2118

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Bain Capital Life Sciences

                            Deal Size : $120.0 million

                            Deal Type : Series C Financing

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                            08

                            Sun Pharmaceutical Industries Limited

                            India arrow
                            German Wound Congress
                            Not Confirmed

                            Sun Pharmaceutical Industries Limited

                            India arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : MM-II

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Moebius Medical

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Sun Pharma-Moebius Injection Shows Pain Relief in Trials

                            Details : MM-II is a novel non-opioid intra-articular injection for treating osteoarthritis knee pain. It leverages multilamellar liposomes to reduce joint friction and wear, providing sustainable pain relief.

                            Product Name : MM-II

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 06, 2024

                            Lead Product(s) : MM-II

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Moebius Medical

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Eupraxia Pharmaceuticals

                            Canada arrow
                            German Wound Congress
                            Not Confirmed

                            Eupraxia Pharmaceuticals

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Fluticasone Propionate

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Raymond James & Associates, Inc.

                            Deal Size : $30.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Eupraxia Pharmaceuticals Announces Overnight Marketed Offering of Approx $30 Million

                            Details : Eupraxia will use net proceeds to fund research activities, including EP-104IAR, a novel, sustained-release corticosteroid formulation for treating osteoarthritis.

                            Product Name : EP-104IAR

                            Product Type : Steroid

                            Upfront Cash : Undisclosed

                            November 03, 2024

                            Lead Product(s) : Fluticasone Propionate

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Raymond James & Associates, Inc.

                            Deal Size : $30.0 million

                            Deal Type : Public Offering

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                            10

                            Saol therapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            Saol therapeutics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : SL-1002

                            Therapeutic Area : Musculoskeletal

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Saol Therapeutics Shares Positive SL-1002 Results for Limb Spasticity

                            Details : SL-1002 is a novel, chemoneurolytic injection, that utilizes Saol's proprietary CYCLOPHLEX™ technology, which is investigated for the treatment of Limb Spasticity.

                            Product Name : SL-1002

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 30, 2024

                            Lead Product(s) : SL-1002

                            Therapeutic Area : Musculoskeletal

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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