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Find Clinical Drug Pipeline Developments & Deals by Nacuity Pharmaceuticals

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          PPS Boston
                          Not Confirmed
                          PPS Boston
                          Not Confirmed

                          Details : NPI-002 is a novel, slow-release, small-molecule product currently undergoing evaluation in early-stage clinical trials for an Intravitreal Implant aimed at delaying cataract progression.

                          Brand Name : NPI-002

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 30, 2024

                          Lead Product(s) : NPI-002

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          PPS Boston
                          Not Confirmed
                          PPS Boston
                          Not Confirmed

                          Details : NPI-001 (AT-001 ) combats rare hereditary forms of dementia. Currently, it is being evaluated in the IND enabling stage for the treatment of Hereditary Cystatin C Amyloid Angiopathy.

                          Brand Name : NPI-001

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 12, 2024

                          Lead Product(s) : Grapiprant

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : IND Enabling

                          Sponsor : Arctic Therapeutics

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          PPS Boston
                          Not Confirmed
                          PPS Boston
                          Not Confirmed

                          Details : NPI-002 is a novel, differentiated, slow-release, small molecule being developed to slow cataract progression. For the treatment of cataract, a sterile intravitreal implant containing NPI-002 has been developed, along with a precision delivery system.

                          Brand Name : NPI-002

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 11, 2023

                          Lead Product(s) : NPI-002

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          PPS Boston
                          Not Confirmed
                          PPS Boston
                          Not Confirmed

                          Details : NPI-001 is an oral, small molecule, proprietary, GMP-grade formulation of N-acetylcysteine amide (NACA) tablets being developed in patients with retinitis pigmentosa (RP) associated with Usher syndrome (USH).

                          Brand Name : NPI-001

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 31, 2023

                          Lead Product(s) : N-acetylcysteine Amide

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          PPS Boston
                          Not Confirmed
                          PPS Boston
                          Not Confirmed

                          Details : NPI-001 is a differentiated, purified, prescription-quality, GMP-grade N-acetylcysteine amide (NACA) being developed to treat a broad set of diseases and conditions associated with oxidative stress and reduced glutathione levels.

                          Brand Name : NPI-001

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          September 13, 2022

                          Lead Product(s) : N-acetylcysteine Amide

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Preclinical

                          Sponsor : Arctic Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          06

                          PPS Boston
                          Not Confirmed
                          PPS Boston
                          Not Confirmed

                          Details : Proceeds from the financing will be used to support the advancement of Nacuity’s clinical trials for NPI-001 and NPI-002 through proof of concept, as well as for general operations.

                          Brand Name : NPI-001

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 15, 2022

                          Lead Product(s) : NPI-001

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Foundation Fighting Blindness

                          Deal Size : $16.5 million

                          Deal Type : Series B Financing

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                          07

                          PPS Boston
                          Not Confirmed
                          PPS Boston
                          Not Confirmed

                          Details : Nanoform and Nacuity have signed a Technology Proof of Concept Agreement. This will apply Nanoform’s award-winning nanoparticle CESS technology to enhance ophthalmic drug delivery of Nacuity’s NPI-001 and NPI-002 drug candidates.

                          Brand Name : NPI-001

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 31, 2021

                          Lead Product(s) : NPI-001

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Recipient : Nanoform

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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