Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : NPI-002
Therapeutic Area : Ophthalmology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nacuity Implants First Patients in Final Cohort of Trial Evaluating NPI-002
Details : NPI-002 is a novel, slow-release, small-molecule product currently undergoing evaluation in early-stage clinical trials for an Intravitreal Implant aimed at delaying cataract progression.
Brand Name : NPI-002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 30, 2024
Lead Product(s) : NPI-002
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Grapiprant
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : Arctic Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Arctic and Nacuity Announce EMA Approval to Initiate Trial of AT-001 for HCCAA
Details : NPI-001 (AT-001 ) combats rare hereditary forms of dementia. Currently, it is being evaluated in the IND enabling stage for the treatment of Hereditary Cystatin C Amyloid Angiopathy.
Brand Name : NPI-001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 12, 2024
Lead Product(s) : Grapiprant
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : Arctic Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NPI-002
Therapeutic Area : Ophthalmology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NPI-002 is a novel, differentiated, slow-release, small molecule being developed to slow cataract progression. For the treatment of cataract, a sterile intravitreal implant containing NPI-002 has been developed, along with a precision delivery system.
Brand Name : NPI-002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 11, 2023
Lead Product(s) : NPI-002
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : N-acetylcysteine Amide
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NPI-001 is an oral, small molecule, proprietary, GMP-grade formulation of N-acetylcysteine amide (NACA) tablets being developed in patients with retinitis pigmentosa (RP) associated with Usher syndrome (USH).
Brand Name : NPI-001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 31, 2023
Lead Product(s) : N-acetylcysteine Amide
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : N-acetylcysteine Amide
Therapeutic Area : Rare Diseases and Disorders
Study Phase : Preclinical
Sponsor : Arctic Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : NPI-001 is a differentiated, purified, prescription-quality, GMP-grade N-acetylcysteine amide (NACA) being developed to treat a broad set of diseases and conditions associated with oxidative stress and reduced glutathione levels.
Brand Name : NPI-001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 13, 2022
Lead Product(s) : N-acetylcysteine Amide
Therapeutic Area : Rare Diseases and Disorders
Highest Development Status : Preclinical
Sponsor : Arctic Therapeutics
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : NPI-001
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Foundation Fighting Blindness
Deal Size : $16.5 million
Deal Type : Series B Financing
Details : Proceeds from the financing will be used to support the advancement of Nacuity’s clinical trials for NPI-001 and NPI-002 through proof of concept, as well as for general operations.
Brand Name : NPI-001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 15, 2022
Lead Product(s) : NPI-001
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Foundation Fighting Blindness
Deal Size : $16.5 million
Deal Type : Series B Financing
Lead Product(s) : NPI-001
Therapeutic Area : Ophthalmology
Study Phase : Phase I
Recipient : Nanoform
Deal Size : Undisclosed
Deal Type : Agreement
Details : Nanoform and Nacuity have signed a Technology Proof of Concept Agreement. This will apply Nanoform’s award-winning nanoparticle CESS technology to enhance ophthalmic drug delivery of Nacuity’s NPI-001 and NPI-002 drug candidates.
Brand Name : NPI-001
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 31, 2021
Lead Product(s) : NPI-001
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I
Recipient : Nanoform
Deal Size : Undisclosed
Deal Type : Agreement
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