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Find Clinical Drug Pipeline Developments & Deals for Nalbuphine Hydrochloride

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01

Pharma Live Expo
Not Confirmed
Pharma Live Expo
Not Confirmed

Details : Haduvio (nalbuphine) is a centrally and peripherally acting investigational therapy which is under development for the treatment of patients with refractory chronic cough.

Product Name : Haduvio

Product Type : Controlled Substance

Upfront Cash : Inapplicable

March 10, 2025

Lead Product(s) : Nalbuphine Hydrochloride

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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02

Pharma Live Expo
Not Confirmed
Pharma Live Expo
Not Confirmed

Details : Haduvio (oral nalbuphine ER) is a centrally and peripherally acting investigational therapy which is under development for the treatment of idiopathic pulmonary fibrosis patients with chronic cough.

Product Name : Haduvio

Product Type : Controlled Substance

Upfront Cash : Inapplicable

February 25, 2025

Lead Product(s) : Nalbuphine Hydrochloride

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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03

Pharma Live Expo
Not Confirmed
Pharma Live Expo
Not Confirmed

Details : The net proceeds will be used to fund the clinical development of company's lead product Haduvio (nalbuphine) for the treatment of Chronic Cough in Idiopathic Pulmonary Fibrosis.

Product Name : Haduvio

Product Type : Controlled Substance

Upfront Cash : Undisclosed

December 16, 2024

Lead Product(s) : Nalbuphine Hydrochloride

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase II

Sponsor : Adage Capital Partners

Deal Size : $50.0 million

Deal Type : Public Offering

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04

Pharma Live Expo
Not Confirmed
Pharma Live Expo
Not Confirmed

Details : Haduvio (oral nalbuphine ER) is a centrally and peripherally acting investigational therapy which is under phase 2 clinical development for the treatment of refractory chronic cough (RCC).

Product Name : Haduvio

Product Type : Controlled Substance

Upfront Cash : Inapplicable

December 03, 2024

Lead Product(s) : Nalbuphine Hydrochloride

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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05

Pharma Live Expo
Not Confirmed
Pharma Live Expo
Not Confirmed

Details : Haduvio (oral nalbuphine ER) is a centrally and peripherally acting investigational therapy which is under development for the treatment of chronic cough in idiopathic pulmonary fibrosis.

Product Name : Haduvio

Product Type : Controlled Substance

Upfront Cash : Inapplicable

October 21, 2024

Lead Product(s) : Nalbuphine Hydrochloride

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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06

Pharma Live Expo
Not Confirmed
Pharma Live Expo
Not Confirmed

Details : Haduvio (oral nalbuphine ER) is a centrally and peripherally acting investigational therapy which is under phase 2 clinical development for the treatment of refractory chronic cough (RCC).

Product Name : Haduvio

Product Type : Controlled Substance

Upfront Cash : Inapplicable

February 11, 2023

Lead Product(s) : Nalbuphine Hydrochloride

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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07

Pharma Live Expo
Not Confirmed
Pharma Live Expo
Not Confirmed

Details : The company will use the net proceeds from the offering for the development of clinical pipeline including its lead product Haduvio (nalbuphine) and for other general and corporate purpose.

Product Name : Haduvio

Product Type : Controlled Substance

Upfront Cash : Undisclosed

September 23, 2022

Lead Product(s) : Nalbuphine Hydrochloride

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase II

Sponsor : SVB Securities

Deal Size : $55.0 million

Deal Type : Public Offering

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08

Pharma Live Expo
Not Confirmed
Pharma Live Expo
Not Confirmed

Details : Primary efficacy endpoint demonstrated 77.3% reduction in daytime cough frequency from baseline with use of Haduvio (nalbuphine ER) compared to 25.7% reduction with placebo, 52% placebo-adjusted reduction in geometric mean percent change in daytime cough...

Product Name : Haduvio

Product Type : Controlled Substance

Upfront Cash : Inapplicable

August 24, 2022

Lead Product(s) : Nalbuphine Hydrochloride

Therapeutic Area : Dermatology

Highest Development Status : Phase II/ Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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09

Pharma Live Expo
Not Confirmed
Pharma Live Expo
Not Confirmed

Details : Company intends to use net proceeds from the private placement for the clinical development of Haduvio (Nalbuphine ER), a mixed ĸ-opioid receptor agonist and µ-opioid receptor antagonist for chronic cough in IPF and working capital and other general co...

Product Name : Haduvio

Product Type : Controlled Substance

Upfront Cash : Undisclosed

July 04, 2022

Lead Product(s) : Nalbuphine Hydrochloride

Therapeutic Area : Pulmonary/Respiratory Diseases

Highest Development Status : Phase II

Sponsor : Frazier Life Sciences

Deal Size : $55.0 million

Deal Type : Private Placement

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10

Pharma Live Expo
Not Confirmed
Pharma Live Expo
Not Confirmed

Details : Haduvio (oral nalbuphine ER) demonstrated statistically significant results on the primary efficacy endpoint as measured by a 4-point reduction in the Worst Itch – Numerical Rating Scale (WI-NRS) (p=0.0157).

Product Name : Haduvio

Product Type : Controlled Substance

Upfront Cash : Inapplicable

June 29, 2022

Lead Product(s) : Nalbuphine Hydrochloride

Therapeutic Area : Dermatology

Highest Development Status : Phase II/ Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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