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Pharmaceuticals","highestDevelopmentStatusID":"8","companyTruncated":"Viracta Therapeutics \/ Sunesis Pharmaceuticals"},{"orgOrder":0,"company":"Viracta Therapeutics","sponsor":"Sunesis Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2021","type":"Merger","leadProduct":"Nanatinostat","moa":"HDAC","graph1":"Oncology","graph2":"Phase II","graph3":"Viracta Therapeutics","amount2":0.12,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0.12,"dosageForm":"Capsule","sponsorNew":"Viracta Therapeutics \/ Sunesis Pharmaceuticals","highestDevelopmentStatusID":"8","companyTruncated":"Viracta Therapeutics \/ Sunesis Pharmaceuticals"},{"orgOrder":0,"company":"Viracta Therapeutics","sponsor":"BVF Partners","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2021","type":"Private 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Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Viracta Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Nanatinostat","moa":"HDAC","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Viracta Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Viracta Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Viracta Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Viracta Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Nanatinostat","moa":"HDAC","graph1":"Oncology","graph2":"Phase II","graph3":"Viracta Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Viracta Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Viracta Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Viracta Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Nanatinostat","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Viracta Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Viracta Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Viracta Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Viracta Therapeutics","sponsor":"Not 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Find Clinical Drug Pipeline Developments & Deals for Nanatinostat

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma Manufacturing 2024
                          Not Confirmed
                          Pharma Manufacturing 2024
                          Not Confirmed

                          Details : Viracta's lead program, Nana-Val evaluates the all-oral combination of nanatinostat & valganciclovir in a Phase 2 clinical trial for the treatment of EBV-positive relapsed/refractory (R/R) lymphoma.

                          Brand Name : Nana-Val

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 14, 2024

                          Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharma Manufacturing 2024
                          Not Confirmed
                          Pharma Manufacturing 2024
                          Not Confirmed

                          Details : Viracta’s lead program VRx-3996 combines nanatinostat and valganciclovir in a Phase 2 trial for EBV-positive relapsed/refractory lymphoma, aiming to address unmet patient needs.

                          Brand Name : VRx-3996

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 15, 2024

                          Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharma Manufacturing 2024
                          Not Confirmed
                          Pharma Manufacturing 2024
                          Not Confirmed

                          Details : Nana-val (nanatinostat with valganciclovir) is an all-oral investigational therapy targeting Epstein-Barr virus (EBV)-associated cancers. It is being evaluated for EBV+ peripheral T-cell lymphoma.

                          Brand Name : Nana-val

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          February 29, 2024

                          Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharma Manufacturing 2024
                          Not Confirmed
                          Pharma Manufacturing 2024
                          Not Confirmed

                          Details : Nana-val (nanatinostat in combination with valganciclovir), a first-in-class, all-oral investigational therapy targeting Epstein-Barr virus (EBV)-associated cancers. It is being evaluated for the treatment of EBV-related nasopharyngeal carcinoma.

                          Brand Name : Nana-val

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 12, 2023

                          Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharma Manufacturing 2024
                          Not Confirmed
                          Pharma Manufacturing 2024
                          Not Confirmed

                          Details : Nana-val (nanatinostat + valganciclovir) is a combination medicine. Nanatinostat is an orally available histone deacetylase (HDAC) inhibitor. It is being evaluated in phase 1/2 clinical trials for the treatment of Epstein-Barr Virus-positive solid tumors...

                          Brand Name : Nana-val

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 04, 2023

                          Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharma Manufacturing 2024
                          Not Confirmed
                          Pharma Manufacturing 2024
                          Not Confirmed

                          Details : Nana-val (nanatinostat) is an oral histone deacetylase inhibitor, selective for specific Class I HDACs isoform. It is currently being investigated in combination with valganciclovir for R/R EBV+ PTCL.

                          Brand Name : Nana-Val

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 28, 2023

                          Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharma Manufacturing 2024
                          Not Confirmed
                          Pharma Manufacturing 2024
                          Not Confirmed

                          Details : Nana-val (nanatinostat and valganciclovir) is an orally available histone deacetylase inhibitor. It is selective for specific isoforms of Class I HDACs, which are key to inducing viral genes that are epigenetically silenced in EBV-associated malignancies...

                          Brand Name : Nana-val

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 19, 2023

                          Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Pharma Manufacturing 2024
                          Not Confirmed
                          Pharma Manufacturing 2024
                          Not Confirmed

                          Details : Nana-val (nanatinostat) is an oral histone deacetylase inhibitor, selective for specific Class I HDACs isoforms, which induces viral genes that are epigenetically silenced in EBV associated malignancies. It is currently being investigated in combination ...

                          Brand Name : Nana-val

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 08, 2023

                          Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharma Manufacturing 2024
                          Not Confirmed
                          Pharma Manufacturing 2024
                          Not Confirmed

                          Details : VRx-3996 (nanatinostat), an orally available HDAC inhibitor, is selective for specific isoforms of Class I HDACs, which are key to inducing viral genes that are epigenetically silenced in Epstein-Barr virus (EBV)-associated malignancies.

                          Brand Name : VRx-3996

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 30, 2022

                          Lead Product(s) : Nanatinostat,Pembrolizumab,Valganciclovir Hydrochloride

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Pharma Manufacturing 2024
                          Not Confirmed
                          Pharma Manufacturing 2024
                          Not Confirmed

                          Details : Nana-val (nanatinostat) is selective for specific isoforms of Class I HDACs, which is key to inducing viral genes that are epigenetically silenced in Epstein-Barr virus (EBV)-associated malignancies.

                          Brand Name : Nana-val

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          September 07, 2022

                          Lead Product(s) : Nanatinostat,Valganciclovir Hydrochloride

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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