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    [{"orgOrder":0,"company":"NantKwest","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Vaccine","year":"2020","type":"Not Applicable","leadProduct":"Avelumab","moa":"PD-L1","graph1":"Oncology","graph2":"Phase I","graph3":"NantKwest","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Suspension for Infusion","sponsorNew":"NantKwest \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"NantKwest \/ Not Applicable"},{"orgOrder":0,"company":"NantKwest","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Avelumab","moa":"IL-15","graph1":"Oncology","graph2":"Phase II","graph3":"NantKwest","amount2":0,"highestDevelopmentShortName":"Ph 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NantKwest"}]

    Find Clinical Drug Pipeline Developments & Deals by NantKwest

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                            01

                            NantKwest

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                            Medlab Asia & Asia Health
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                            NantKwest

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : hAd5-S-Fusion+N-ETSD Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Recipient : ImmunityBio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            ImmunityBio and NantKwest Begin Dosing Participants in Global Trials for Novel COVID-19 Vaccine

                            Details : hAd5 S+N is unique in targeting both the spike (S) and nucleocapsid (N) proteins of the SARS-CoV-2 virus. First COVID-19 vaccine trials designed to deliver both S and N SARS-CoV-2 viral proteins via multiple routes—subcutaneous, sublingual, and oral.

                            Brand Name : hAd5 S+N

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            March 08, 2021

                            Lead Product(s) : hAd5-S-Fusion+N-ETSD Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Recipient : ImmunityBio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            NantKwest

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                            Medlab Asia & Asia Health
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                            NantKwest

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Aldoxorubicin HCl,PD-L1 t-haNK,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Recipient : CytRx Corporation

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            CytRx Reports Use of Aldoxorubicin in Phase 2 Clinical Trials Yielding Positive Interim Data on Survival Rates...

                            Details : NantKwest and ImmunityBio’s QUILT 88 Trial shows novel combination immunotherapy, which includes which include CytRx’s licensed drug aldoxorubicin, has more than doubled historic median survival rates in patients.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 15, 2021

                            Lead Product(s) : Aldoxorubicin HCl,PD-L1 t-haNK,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Recipient : CytRx Corporation

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            NantKwest

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                            Medlab Asia & Asia Health
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                            NantKwest

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : N-803,BCG Vaccine

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Recipient : ImmunityBio

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Immunitybio and Nantkwest to Merge, Creating a Leading Immunotherapy and Cell Therapy Company

                            Details : The combination of NantKwest’s Natural Killer (NK) cell platform and ImmunityBio’s immunotherapy fusion protein, immunomodulator, and adenovirus platforms have already resulted in complete responses in late stage, difficult to treat metastatic cancer...

                            Brand Name : Anktiva

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            December 21, 2020

                            Lead Product(s) : N-803,BCG Vaccine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Recipient : ImmunityBio

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            04

                            NantKwest

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                            Medlab Asia & Asia Health
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                            NantKwest

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : Aldoxorubicin HCl,N-803,PD-L1 t-haNK

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : ImmunityBio

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            Immunitybio and Nantkwest to Merge, Creating a Leading Immunotherapy and Cell Therapy Company

                            Details : The transaction is structured as a tax-free 100% stock-for-stock merger, with ImmunityBio to reverse merge with NantKwest. Following the closing of the transaction, the combined company will assume the ImmunityBio name and continue to be listed on the NA...

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            December 21, 2020

                            Lead Product(s) : Aldoxorubicin HCl,N-803,PD-L1 t-haNK

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : ImmunityBio

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            05

                            NantKwest

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                            Medlab Asia & Asia Health
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                            NantKwest

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : hAd5-S-Fusion+N-ETSD Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Recipient : ImmunityBio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            ImmunityBio, NantKwest Announce Positive Interim Phase 1 Safety Data of hAd5 COVID-19 Vaccine Dose Study

                            Details : Developed by ImmunityBio and manufactured by NantKwest, this second generation hAd5-vector vaccine is unique in targeting both spike and nucleocapsid SARS-CoV-2 proteins. Low dose cohort reports no serious adverse events, high dose cohort safety analysis...

                            Brand Name : hAd5

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            November 10, 2020

                            Lead Product(s) : hAd5-S-Fusion+N-ETSD Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Recipient : ImmunityBio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            NantKwest

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                            Medlab Asia & Asia Health
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                            NantKwest

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : hAd5-S-Fusion+N-ETSD Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase I

                            Recipient : ImmunityBio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            ImmunityBio, NantKwest Announce First Patient Dosed in Phase 1 Clinical Trial of Novel COVID-19 Vaccine Candid...

                            Details : First patient has been dosed in the Phase 1 clinical trial of hAd5-COVID-19, a novel COVID-19 vaccine candidate that targets the inner nucleocapsid (N) and the outer spike (S) protein, engineered to activate both T cells and antibodies against the corona...

                            Brand Name : hAd5

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            October 21, 2020

                            Lead Product(s) : hAd5-S-Fusion+N-ETSD Vaccine

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase I

                            Recipient : ImmunityBio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            NantKwest

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                            Medlab Asia & Asia Health
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                            NantKwest

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : PD-L1 t-haNK,N-803,Aldoxorubicin HCl

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : ImmunityBio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            NantKwest, ImmunityBio Add Third-Line Cohort to Phase 2 Pancreatic Cancer Trial

                            Details : Third cohort added to independently evaluate the efficacy of NantKwest’s PD-L1 t-haNK natural killer cells plus ImmunityBio’s IL-15 superagonist AnktivaÔ (N-803) in third-line or greater therapy for patients with locally advanced or metastatic pancr...

                            Brand Name : PD-L1 t-haNK

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            October 06, 2020

                            Lead Product(s) : PD-L1 t-haNK,N-803,Aldoxorubicin HCl

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : ImmunityBio

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            NantKwest

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                            Medlab Asia & Asia Health
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                            NantKwest

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : BM-Allo.MSC

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            NantKwest Announces FDA Authorization of IND Application for Mesenchymal Stem Cell Product for the Treatment o...

                            Details : Preliminary data from NantKwest collaborators suggests mesenchymal stem cell treatments may benefit COVID-19 patients with acute respiratory distress syndrome and cytokine storm.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            May 18, 2020

                            Lead Product(s) : BM-Allo.MSC

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            NantKwest

                            U.S.A arrow
                            Medlab Asia & Asia Health
                            Not Confirmed

                            NantKwest

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                            Medlab Asia & Asia Health
                            Not Confirmed
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                            Lead Product(s) : PD-L1 t-haNK,N-803,Aldoxorubicin HCl

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            NantKwest and ImmunityBio to Initiate a Phase 2 Study of Immunotherapy for Metastatic Pancreatic Cancer

                            Details : Open-label, randomized Phase 2 study will evaluate combination immunotherapy, including NantKwest’s PD-L1 tumor-targeted natural killer cells and ImmunityBio’s IL-15 superagonist N-803 with standard of care versus standard of care alone.

                            Brand Name : Undisclosed

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            May 14, 2020

                            Lead Product(s) : PD-L1 t-haNK,N-803,Aldoxorubicin HCl

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            NantKwest

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                            Medlab Asia & Asia Health
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                            NantKwest

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                            Medlab Asia & Asia Health
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                            Lead Product(s) : HaNK

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Undisclosed

                            Sponsor : ImmunityBio

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            NantKwest and ImmunityBio Announce Therapeutics and Vaccines for Combatting Covid-19

                            Details : Under this collaboration, NantKwest and ImmunityBio are combining their resources to design and develop therapeutics and vaccines for COVID-19.

                            Brand Name : Undisclosed

                            Molecule Type : Vaccine

                            Upfront Cash : Undisclosed

                            April 14, 2020

                            Lead Product(s) : HaNK

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Undisclosed

                            Sponsor : ImmunityBio

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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