Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : RO-104
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Recipient : RevOpsis Therapeutics
Deal Size : $1.8 million
Deal Type : Funding
RevOpsis Wins $1.8M Grant for Ophthalmic Therapy R&D Advancement
Details : The SBIR grant will fund critical R&D activities, including multidose GMP toxicology studies in nonhuman primates for RO-104, a first-in-class fully human modular tri-specific biologic.
Brand Name : RO-104
Molecule Type : Large molecule
Upfront Cash : Undisclosed
October 15, 2024
Lead Product(s) : RO-104
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Recipient : RevOpsis Therapeutics
Deal Size : $1.8 million
Deal Type : Funding
Lead Product(s) : IVMED-85
Therapeutic Area : Ophthalmology
Study Phase : Phase I/ Phase II
Recipient : iVeena
Deal Size : $0.3 million
Deal Type : Funding
iVeena Awarded NEI-SBIR Grant for Progressive Myopia Drug Candidate IVMED-85
Details : The grant will be used for the development of IVMED-85, an investigational eyedrop formulation containing copper intended for treatment of pediatric myopia. IVMED-85 will be the first eye drop inducing both scleral and corneal crosslinking for myopia con...
Brand Name : IVMED-85
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 26, 2023
Lead Product(s) : IVMED-85
Therapeutic Area : Ophthalmology
Highest Development Status : Phase I/ Phase II
Recipient : iVeena
Deal Size : $0.3 million
Deal Type : Funding
Lead Product(s) : PTG-630
Therapeutic Area : Neurology
Study Phase : Preclinical
Recipient : Praetego
Deal Size : $0.3 million
Deal Type : Funding
Praetego Awarded $0.3M by National Eye Institute to Advance Novel Oral Drug for Diabetic Retinopathy
Details : Praetego's NEI grant expands PTG-630 to a third indication and builds upon promising findings in both Alzheimer's disease and diabetic peripheral neuropathy. PTG-630 has demonstrated remarkable potency as an AGE inhibitor.
Brand Name : PTG-630
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 01, 2023
Lead Product(s) : PTG-630
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Recipient : Praetego
Deal Size : $0.3 million
Deal Type : Funding
Details : TRE-515 is a novel first-in-class drug, which has been shown to prevent demyelination, and even facilitate remyelination, in multiple demyelinating disease mouse models. Furthermore, the FDA has designated TRE-515 an Orphan Drug in the treatment of ON.
Brand Name : TRE-515
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 19, 2022
Lead Product(s) : I27-Breg
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
NIH Scientists Discover New B Cell that Tempers Autoimmunity
Details : Infusions of purified IL-27 regulatory B cells (I27-Breg ) reduced symptoms in mouse models of multiple sclerosis (MS) and the eye disease autoimmune uveitis. The research suggests the cells may play a role in future human therapies.
Brand Name : I27-Breg
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 02, 2021
Lead Product(s) : I27-Breg
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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