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Find Clinical Drug Pipeline Developments & Deals by National Institute of Allergy and Infectious Diseases

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          BioAsia
                          Not Confirmed

                          Details : The collaboration aims for evaluating Chrysalin (rusalatide acetate), a regenerative peptide drug, for the treatment of Cutaneous Radiation Injury (CRI).

                          Product Name : Chrysalin

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          November 18, 2024

                          Lead Product(s) : Rusalatide Acetate

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : IND Enabling

                          Recipient : Chrysalis BioTherapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          02

                          BioAsia
                          Not Confirmed

                          Details : NIAID will be conducting and sponsoring clinical trial to accelerate the Phase I first-in-human trial of the company’s next-generation COVID-19 mRNA vaccine candidate.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          November 13, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Recipient : PopVax

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          03

                          BioAsia
                          Not Confirmed

                          Details : NIAID will be conducting and sponsoring clinical trial to accelerate Emergex vaccine, CoronaTcP, designed to be broadly effective against Betacoronavirus infections, including SARS-CoV-1.

                          Product Name : Undisclosed

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          October 02, 2024

                          Lead Product(s) : PepGNP-COVID19

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Recipient : National Institute of Allergy and Infectious Diseases

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          04

                          BioAsia
                          Not Confirmed

                          Details : EV68-228-N, a human monoclonal IgG1 against the capsid of enterovirus D68 (EV-D68) designed as an intravenous therapeutic for the treatment of acute flaccid myelitis (AFM).

                          Product Name : EV68-228-N

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          June 28, 2024

                          Lead Product(s) : EV68-228-N

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase I

                          Recipient : KBio

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          BioAsia
                          Not Confirmed

                          Details : The company will manufacture the PLX-R18 cell therapy and conduct in vitro and in vivo studies to develop it as a potential treatment for hematopoietic complications of the acute radiation syndrome.

                          Product Name : PLX-R18

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          June 06, 2024

                          Lead Product(s) : Avoplacel

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase I

                          Recipient : Pluri

                          Deal Size : $4.2 million

                          Deal Type : Funding

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                          06

                          BioAsia
                          Not Confirmed

                          Details : Xocova® (ensitrelvir fumaric acid) is an antiviral drug for COVID-19 which suppresses the replication of SARS-CoV-2 by selectively inhibiting 3CL protease.

                          Product Name : Xocova

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          May 13, 2024

                          Lead Product(s) : Ensitrelvir Fumaric Acid

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Recipient : Shionogi

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          BioAsia
                          Not Confirmed

                          Details : The collaboration aims to evaluate RLS-0071, a novel 15-amino acid peptide dual-targeting anti-inflammatory inhibitor, to mitigate gastrointestinal effects of ARS in a preclinical mouse model.

                          Product Name : RLS-0071

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          March 28, 2024

                          Lead Product(s) : RLS-0071

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Preclinical

                          Recipient : ReAlta Life Sciences

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          08

                          BioAsia
                          Not Confirmed

                          Details : The funding will support preclinical studies evaluating the breadth of protection and immune response induced by the company’s lead, broad-spectrum influenza vaccine candidate, OVX836 against pandemic influenza strains.

                          Product Name : OVX836

                          Product Type : Vaccine

                          Upfront Cash : Undisclosed

                          December 05, 2023

                          Lead Product(s) : OVX836

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Recipient : Osivax

                          Deal Size : $1.5 million

                          Deal Type : Funding

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                          09

                          BioAsia
                          Not Confirmed

                          Details : OCU500 is a mucosal vaccine candidate which is delivered via two different mucosal routes, inhalation into the lungs and as a nasal spray, which is investigated for the treatment of COVID-19 and influenza (flu).

                          Product Name : OCU500

                          Product Type : Vaccine

                          Upfront Cash : Not Applicable

                          October 10, 2023

                          Lead Product(s) : OCU500

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I/ Phase II

                          Recipient : Ocugen

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          BioAsia
                          Not Confirmed

                          Details : The funding will be used to conduct nonclinical and clinical studies to advance its pan-coronavirus protease inhibitor ALG-097558, a potent, pan-coronavirus small molecule inhibitor of the viral 3CL protease, into future Phase 2/3 studies.

                          Product Name : ALG-097558

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 03, 2023

                          Lead Product(s) : ALG-097558

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Recipient : Aligos Therapeutics

                          Deal Size : $8.5 million

                          Deal Type : Funding

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