Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed
Therapeutic Area : Psychiatry/Psychology
Study Phase : Preclinical
Recipient : EpiVario
Deal Size : $0.2 million
Deal Type : Funding
EpiVario Awarded SBIR Grant from NIH to Develop Treatments for Opioid Use Disorder
Details : The grant will be used to advance the company's research towards developing a novel epigenetic regulator as a treatment for opioid use disorder (OUD).
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 01, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Preclinical
Recipient : EpiVario
Deal Size : $0.2 million
Deal Type : Funding
Lead Product(s) : Ibogaine
Therapeutic Area : Psychiatry/Psychology
Study Phase : Preclinical
Recipient : Gilgamesh Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Funding
Gilgamesh Awarded $14M Grant for Cardiac-Safe Ibogaine Analog in Opioid Use Disorder
Details : The funding aims to support the company's ongoing development of GM-3009 (ibogaine), a Kappa opioid receptor agonist. It is evaluated in the Preclinical trials for Opioid-Related Disorders.
Brand Name : GM-3009
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 14, 2024
Lead Product(s) : Ibogaine
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Preclinical
Recipient : Gilgamesh Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Funding
Lead Product(s) : Naltrexone,Bupropion Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Study Phase : Preclinical
Recipient : BioCorRx
Deal Size : $11.0 million
Deal Type : Funding
BioCorRx Awarded $11M NIDA Grant for BICX104 Naltrexone Implant for MUD Treatment
Details : BioCorRx will focus funding on clinical development of BICX104 (naltrexone) in combination with Bupropion, currently in preclinical studies for methamphetamine use disorder.
Brand Name : BICX104
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 28, 2024
Lead Product(s) : Naltrexone,Bupropion Hydrochloride
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Preclinical
Recipient : BioCorRx
Deal Size : $11.0 million
Deal Type : Funding
Lead Product(s) : SBP-9330
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Recipient : Camino Pharma
Deal Size : $9.0 million
Deal Type : Funding
$9 Million NIH Grant Advances Drug to Treat Nicotine Addiction
Details : The net proceeds will fund longer toxicology studies and manufacturing of SBP-9330, a small molecule targeting mGlu2 receptor, to support planned Phase 2 trials for nicotine cessation.
Brand Name : SBP-9330
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 06, 2024
Lead Product(s) : SBP-9330
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Recipient : Camino Pharma
Deal Size : $9.0 million
Deal Type : Funding
Lead Product(s) : CSX-1004
Therapeutic Area : Psychiatry/Psychology
Study Phase : IND Enabling
Recipient : Cessation Therapeutics
Deal Size : $14.8 million
Deal Type : Funding
Details : The funding will support development of a subcutaneous formulation of its anti-fentanyl monoclonal antibody, CSX-1004 SQ, an investigational product that has successfully entered Phase 1 studies for the reversal of acute opioid over dose of fentanyl and ...
Brand Name : CSX-1004
Molecule Type : Large molecule
Upfront Cash : Undisclosed
October 18, 2023
Lead Product(s) : CSX-1004
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : IND Enabling
Recipient : Cessation Therapeutics
Deal Size : $14.8 million
Deal Type : Funding
Lead Product(s) : Cebranopadol
Therapeutic Area : Psychiatry/Psychology
Study Phase : IND Enabling
Recipient : Tris Pharma Inc
Deal Size : $16.6 million
Deal Type : Funding
Details : Funding will support the studies of Cebranopadol, the first and only full, dual NOP/MOP receptor agonist and has demonstrated reduced cocaine and heroin self-administration and drug-seeking behaviors, reinforcing its potential as an effective treatment f...
Brand Name : TRN-228
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 28, 2023
Lead Product(s) : Cebranopadol
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : IND Enabling
Recipient : Tris Pharma Inc
Deal Size : $16.6 million
Deal Type : Funding
Lead Product(s) : STC-004
Therapeutic Area : Neurology
Study Phase : Preclinical
Recipient : SiteOne Therapeutics
Deal Size : $15.0 million
Deal Type : Funding
Details : The funding will be used for the development of SiteOne's selective NaV1.8 inhibitor, STC-004, an investigational, non-opioid treatment for acute and chronic pain conditions.
Brand Name : STC-004
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 18, 2023
Lead Product(s) : STC-004
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Recipient : SiteOne Therapeutics
Deal Size : $15.0 million
Deal Type : Funding
Lead Product(s) : OMS527
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Recipient : Omeros
Deal Size : $6.6 million
Deal Type : Funding
Details : The funding will be used to develop Omeros’ lead orally administered compound from its proprietary phosphodiesterase 7 (PDE7) program OMS527 for the treatment of cocaine use disorder (CUD).
Brand Name : OMS527
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 10, 2023
Lead Product(s) : OMS527
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Recipient : Omeros
Deal Size : $6.6 million
Deal Type : Funding
Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Recipient : Stalicla
Deal Size : Undisclosed
Deal Type : Agreement
Details : The agreement covers the clinical development program of STP7 (mavoglurant) to treat patients diagnosed with cocaine use disorder (CUD), including a Phase 3 study.
Brand Name : STP7
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 08, 2023
Lead Product(s) : Mavoglurant
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Recipient : Stalicla
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : PPL-138
Therapeutic Area : Psychiatry/Psychology
Study Phase : Preclinical
Recipient : Phoenix Pharmalabs
Deal Size : $8.7 million
Deal Type : Funding
Details : Funding from the grant will support the study of company’s lead compound, PPL-138, for the treatment of cocaine use disorder (CUD) and the cost of advancing PPL-138 through its remaining preclinical studies and through Phase 1 human clinical trials.
Brand Name : PPL-138
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 06, 2022
Lead Product(s) : PPL-138
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Preclinical
Recipient : Phoenix Pharmalabs
Deal Size : $8.7 million
Deal Type : Funding
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