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Find Clinical Drug Pipeline Developments & Deals by National Institutes of Health
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The collaboration aims to evaluate DSP-5336 (enzomenib), an oral, small molecule designed to inhibit the menin and KMT2A protein interaction present in certain difficult to treat cancers.
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The funding aims to support the OMS527 is an orally bioavailable, small molecule antagonist of PDE7. It is being evaluated to treat Cocaine Use Disorder.
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NIH has granted the company a license to a next-generation vaccine antigen (DS2), designed for use in prophylactic vaccines against Respiratory Syncytial Virus (RSV).
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Under the agreement, Syena will expand its pipeline of engineered T-Cell Receptor-Natural Killer (TCR-NK) cell therapies targeting NY-ESO-1, SY-101, by gaining NIH's intellectual property related to a library of TCRs directed against multiple cancer neoa...
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H1ssF-3928 mRNA-LNP (based on mRNA platform), is an influenza vaccine, which is being investigated for safety and its ability to induce a strong and broad immunity against a variety of strains.
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Under the licensing agreement, Eureka will develop and commercialize a novel antibody targeting MSLN, a potentially transformative T-cell therapy for solid tumors, in combination with ARTEMIS® T-cell receptor platform.
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Tecentriq (atezolizumab) binds to PD-L1 and blocks it from binding to another checkpoint protein, PD-1. This helps T cells regain their ability to kill tumor cells.
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The single-site trial will enroll up to 100 people aged 16 to 69 years old, to understand rare but potentially serious systemic allergic reactions from, a first dose of COVID-19 mRNA vaccines Comiranty.
Details :
HEPLISAV-B [Hepatitis B Vaccine (Recombinant), Adjuvanted] Solution for Intramuscular Injection,B is indicated for prevention of infection caused by all known subtypes of hepatitis B virus.
Product Name : Heplisav-B
Product Type : Vaccine
Upfront Cash : Inapplicable
October 22, 2022
Lead Product(s) :
Hepatitis B Vaccine Recombinant, Adjuvanted
Details :
Using patient-derived retina organoids, the discovered that a type of LCA caused by mutations in the AAV-based NPHP5 Gene Thearapy (also called IQCB1) gene leads to severe defects in the primary cilium, a structure found in nearly all cells of the body.
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