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    [{"orgOrder":0,"company":"Mereo BioPharma Group","sponsor":"Oncologie","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"UNITED KINGDOM","productType":"Large molecule","year":"2020","type":"Licensing Agreement","leadProduct":"Navicixizumab","moa":"DLL4","graph1":"Oncology","graph2":"Phase I","graph3":"Mereo BioPharma Group","amount2":0.31,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.31,"dosageForm":"","sponsorNew":"Mereo BioPharma Group \/ Oncologie","highestDevelopmentStatusID":"6","companyTruncated":"Mereo BioPharma Group \/ Oncologie"},{"orgOrder":0,"company":"Qiagen","sponsor":"OncXerna Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2021","type":"Licensing Agreement","leadProduct":"Navicixizumab","moa":"Dll4-Notch1","graph1":"Oncology","graph2":"Phase I","graph3":"Qiagen","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Qiagen \/ OncXerna Therapeutics","highestDevelopmentStatusID":"6","companyTruncated":"Qiagen \/ OncXerna Therapeutics"},{"orgOrder":0,"company":"OncXerna Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"Navicixizumab","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"OncXerna Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"OncXerna Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"OncXerna Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"OncXerna Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"Navicixizumab","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"OncXerna Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"OncXerna Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"OncXerna Therapeutics \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals for Navicixizumab

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                            01

                            OncXerna Therapeutics

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                            CPhI India 2024
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                            OncXerna Therapeutics

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                            Lead Product(s) : Navicixizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            OncXerna Therapeutics Doses First Patient in Phase 2 Trial Evaluating Navicixizumab Alone or in Combination wi...

                            Details : Navicixizumab is an anti-DLL4/VEGF bispecific antibody product candidate that demonstrated antitumor activity in patients who were previously treated with Avastin® (bevacizumab) in a Phase 1b clinical trial.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 08, 2022

                            Lead Product(s) : Navicixizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            OncXerna Therapeutics

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                            CPhI India 2024
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                            OncXerna Therapeutics

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                            Lead Product(s) : Navicixizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            OncXerna Therapeutics Announces Journal of Clinical Oncology Publication Featuring Phase 1b Data of Navicixizu...

                            Details : Overall response rate (ORR) of 43% and median duration of response of 6 months seen with an anti-DLL4/VEGF bispecific antibody, navicixizumab in combination with paclitaxel heavily pretreated platinum-resistant ovarian cancer patients.

                            Brand Name : OMP-305B83

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 21, 2022

                            Lead Product(s) : Navicixizumab,Paclitaxel

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Qiagen

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                            CPhI India 2024
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                            Qiagen

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                            Lead Product(s) : Navicixizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : OncXerna Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            QIAGEN and OncXerna Therapeutics Sign Diagnostic Agreements

                            Details : QIAGEN and OncXerna enter into a global master agreement to advance the development of the Xerna™ TME panel as a potential Next Generation Sequencing (NGS) companion diagnostic for OncXerna’s Navicixizumab.

                            Brand Name : OMP-305B83

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            August 09, 2021

                            Lead Product(s) : Navicixizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : OncXerna Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            04

                            Mereo BioPharma Group

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                            CPhI India 2024
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                            Mereo BioPharma Group

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                            CPhI India 2024
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                            Lead Product(s) : Navicixizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Oncologie

                            Deal Size : $306.0 million

                            Deal Type : Licensing Agreement

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                            Mereo BioPharma and Oncologie Enter into Global Licensing Agreement for Navicixizumab

                            Details : Under the terms and conditions of the agreement, Oncologie receives exclusive global license to develop and commercialize navicixizumab.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : $4.0 million

                            January 13, 2020

                            Lead Product(s) : Navicixizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Oncologie

                            Deal Size : $306.0 million

                            Deal Type : Licensing Agreement

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