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Find Clinical Drug Pipeline Developments & Deals for Navicixizumab

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Navicixizumab is an anti-DLL4/VEGF bispecific antibody product candidate that demonstrated antitumor activity in patients who were previously treated with Avastin® (bevacizumab) in a Phase 1b clinical trial.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 08, 2022

                          Lead Product(s) : Navicixizumab,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Overall response rate (ORR) of 43% and median duration of response of 6 months seen with an anti-DLL4/VEGF bispecific antibody, navicixizumab in combination with paclitaxel heavily pretreated platinum-resistant ovarian cancer patients.

                          Brand Name : OMP-305B83

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 21, 2022

                          Lead Product(s) : Navicixizumab,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : QIAGEN and OncXerna enter into a global master agreement to advance the development of the Xerna™ TME panel as a potential Next Generation Sequencing (NGS) companion diagnostic for OncXerna’s Navicixizumab.

                          Brand Name : OMP-305B83

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          August 09, 2021

                          Lead Product(s) : Navicixizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : OncXerna Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Under the terms and conditions of the agreement, Oncologie receives exclusive global license to develop and commercialize navicixizumab.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : $4.0 million

                          January 13, 2020

                          Lead Product(s) : Navicixizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Oncologie

                          Deal Size : $306.0 million

                          Deal Type : Licensing Agreement

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