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    [{"orgOrder":0,"company":"Neurocrine Biosciences","sponsor":"Xenon Pharmaceuticals Inc","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"NBI-921352","moa":"Nav1.6 channel","graph1":"Neurology","graph2":"Phase II","graph3":"Neurocrine Biosciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Neurocrine Biosciences \/ Xenon Pharmaceuticals Inc","highestDevelopmentStatusID":"8","companyTruncated":"Neurocrine Biosciences \/ Xenon Pharmaceuticals Inc"},{"orgOrder":0,"company":"Neurocrine Biosciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"NBI-921352","moa":"Nav1.6 channel","graph1":"Neurology","graph2":"Phase II","graph3":"Neurocrine Biosciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Neurocrine Biosciences \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Neurocrine Biosciences \/ Inapplicable"},{"orgOrder":0,"company":"Neurocrine Biosciences","sponsor":"Xenon Pharmaceuticals Inc","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"NBI-921352","moa":"Nav1.6 channel","graph1":"Neurology","graph2":"Phase II","graph3":"Neurocrine Biosciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Neurocrine Biosciences \/ Xenon Pharmaceuticals Inc","highestDevelopmentStatusID":"8","companyTruncated":"Neurocrine Biosciences \/ Xenon Pharmaceuticals Inc"},{"orgOrder":0,"company":"Xenon Pharmaceuticals Inc","sponsor":"Neurocrine Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"CANADA","productType":"Other Small Molecule","year":"2021","type":"Collaboration","leadProduct":"NBI-921352","moa":"Nav1.6 channel","graph1":"Neurology","graph2":"Phase II","graph3":"Xenon Pharmaceuticals Inc","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Xenon Pharmaceuticals Inc \/ Neurocrine Biosciences","highestDevelopmentStatusID":"8","companyTruncated":"Xenon Pharmaceuticals Inc \/ Neurocrine Biosciences"},{"orgOrder":0,"company":"Xenon Pharmaceuticals Inc","sponsor":"Neurocrine Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"CANADA","productType":"Other Small Molecule","year":"2022","type":"Collaboration","leadProduct":"NBI-921352","moa":"Nav1.6 channel","graph1":"Neurology","graph2":"Phase II","graph3":"Xenon Pharmaceuticals Inc","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Xenon Pharmaceuticals Inc \/ Neurocrine Biosciences","highestDevelopmentStatusID":"8","companyTruncated":"Xenon Pharmaceuticals Inc \/ Neurocrine Biosciences"}]

    Find Clinical Drug Pipeline Developments & Deals for NBI-921352

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    NBI-921352

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                            01

                            Neurocrine Biosciences

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                            Neurocrine Biosciences

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Xenon Pharmaceuticals Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Xenon Pharmaceuticals Provides Update on Partnered Program with Neurocrine Biosciences

                            Details : NBI-921352, an investigational, selective sodium channel 1.6 inhibitor (Nav1.6) currently under development in adult patients with focal onset seizures (FOS), failed to demonstrate meaningful reduction in seizure frequency.

                            Product Name : NBI-921352

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 11, 2023

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Xenon Pharmaceuticals Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Xenon Pharmaceuticals Inc

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                            Xenon Pharmaceuticals Inc

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Neurocrine Biosciences

                            Deal Size : $1,775.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Xenon Pharmaceuticals Announces Collaboration with Neurocrine Biosciences Achieves $15.0 Million Regulatory Mi...

                            Details : Xenon has an ongoing collaboration with Neurocrine Biosciences to develop treatments for epilepsy. Neurocrine Biosciences has an exclusive license to XEN901, now known as NBI-921352, a selective Nav1.6 sodium channel inhibitor.

                            Product Name : NBI-921352

                            Product Type : Other Small Molecule

                            Upfront Cash : $50.0 million

                            December 01, 2022

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Neurocrine Biosciences

                            Deal Size : $1,775.0 million

                            Deal Type : Collaboration

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                            03

                            Neurocrine Biosciences

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neurocrine Biosciences Presents Demographic and Clinical Characteristics Data of Pediatric Patients with SCN8A...

                            Details : NBI-921352 is an investigational, selective sodium channel 1.6 inhibitor (Nav1.6) currently under development for the potential treatment of SCN8A developmental and epileptic encephalopathy (SCN8A-DEE) in children and adults.

                            Product Name : NBI-921352

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 12, 2022

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Xenon Pharmaceuticals Inc

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Neurocrine Biosciences

                            Deal Size : $1,775.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Xenon Pharmaceuticals Announces Collaboration with Neurocrine Biosciences Achieves $10.0 Million Regulatory Mi...

                            Details : Xenon ongoing collaboration with Neurocrine Biosciences to develop treatments including XEN901, now known as NBI-921352 a clinical stage selective Nav1.6 sodium channel inhibitor with potential in SCN8A developmental and epileptic encephalopathy and othe...

                            Product Name : NBI-921352

                            Product Type : Other Small Molecule

                            Upfront Cash : $50.0 million

                            August 09, 2021

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Neurocrine Biosciences

                            Deal Size : $1,775.0 million

                            Deal Type : Collaboration

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                            05

                            Neurocrine Biosciences

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                            Neurocrine Biosciences

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                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Study Phase : Phase I

                            Sponsor : Xenon Pharmaceuticals Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Neurocrine Biosciences and Xenon Pharmaceuticals Provide Regulatory Update on Ongoing Collaboration to Develop...

                            Details : U.S. Food and Drug Administration (FDA) Requests Additional Non-Clinical Data to Support Dose Justification Before Initiation of a Phase II Clinical Trial with NBI-921352 in Pediatric SCN8A-DEE Patients.

                            Product Name : NBI-921352

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 10, 2020

                            Lead Product(s) : NBI-921352

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase I

                            Sponsor : Xenon Pharmaceuticals Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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