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Find Clinical Drug Pipeline Developments & Deals for NBI-921352

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                          Top Deals by Deal Size (USD bn)

                          01

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : NBI-921352, an investigational, selective sodium channel 1.6 inhibitor (Nav1.6) currently under development in adult patients with focal onset seizures (FOS), failed to demonstrate meaningful reduction in seizure frequency.

                          Brand Name : NBI-921352

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 09, 2023

                          Lead Product(s) : NBI-921352

                          Therapeutic Area : Rare Diseases and Disorders

                          Highest Development Status : Phase II

                          Sponsor : Xenon Pharmaceuticals Inc

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : NBI-921352 is an investigational, selective sodium channel 1.6 inhibitor (Nav1.6) currently under development for the potential treatment of SCN8A developmental and epileptic encephalopathy (SCN8A-DEE) in children and adults.

                          Brand Name : NBI-921352

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 02, 2022

                          Lead Product(s) : NBI-921352

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : Xenon has an ongoing collaboration with Neurocrine Biosciences to develop treatments for epilepsy. Neurocrine Biosciences has an exclusive license to XEN901, now known as NBI-921352, a selective Nav1.6 sodium channel inhibitor.

                          Brand Name : NBI-921352

                          Molecule Type : Small molecule

                          Upfront Cash : $6.7 million

                          January 12, 2022

                          Lead Product(s) : NBI-921352

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Neurocrine Biosciences

                          Deal Size : $15.0 million

                          Deal Type : Collaboration

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                          04

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : Xenon ongoing collaboration with Neurocrine Biosciences to develop treatments including XEN901, now known as NBI-921352 a clinical stage selective Nav1.6 sodium channel inhibitor with potential in SCN8A developmental and epileptic encephalopathy and othe...

                          Brand Name : NBI-921352

                          Molecule Type : Small molecule

                          Upfront Cash : $50.0 million

                          September 08, 2021

                          Lead Product(s) : NBI-921352

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Neurocrine Biosciences

                          Deal Size : $1,775.0 million

                          Deal Type : Collaboration

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                          05

                          euroPLX 86 Munich
                          Not Confirmed
                          euroPLX 86 Munich
                          Not Confirmed

                          Details : U.S. Food and Drug Administration (FDA) Requests Additional Non-Clinical Data to Support Dose Justification Before Initiation of a Phase II Clinical Trial with NBI-921352 in Pediatric SCN8A-DEE Patients.

                          Brand Name : XEN901

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 08, 2020

                          Lead Product(s) : NBI-921352

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Xenon Pharmaceuticals Inc

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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