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Find Clinical Drug Pipeline Developments & Deals for NCGC00024995-03
INJECTABLE;INJECTION - 6MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**, POWDER;INTRAVENOUS - 100MG/VIAL
Details :
Abraxane-Generic (paclitaxel) is a microtubule inhibitor indicated for metastatic breast cancer, locally advanced or metastatic non-small cell lung cancer & metastatic pancreatic adenocarcinoma.
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IMP321 (eftilagimod alpha) a soluble LAG-3 protein and MHC Class II agonist is being evaluated in combination with paclitaxel under evaluation for treatment of metastatic breast carcinoma.
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VCN-01 is being evaluated in combination with standard-of-care (SoC) chemotherapy (gemcitabine/nab-paclitaxel) as a first line therapy for patients with pancreatic ductal adenocarcinoma (PDAC).
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Oregovomab, a murine monoclonal antibody against CA 125, in combination with paclitaxel and carboplatin, is being investigated in patients with newly diagnosed advanced epithelial ovarian cancer.
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CTX-009 is a bispecific DLL4/VEGF-A antibody, it is being evaluated in combination with paclitaxel for the treatment of patients with metastatic or locally advanced biliary tract tumors.
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Apexelsin (albumin bound-paclitaxel) a microtubule inhibitor indicated for metastatic breast cancer, locally advanced or metastatic non-small cell lung cancer & metastatic pancreatic adenocarcinoma.
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Under the license agreement, MacroGenics will focus on the development of Zynyz (retifanlimab), which is being evaluated in the late-stage trial studies for treating Squamous Cell Anal Carcinoma.
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Tuoyi (toripalimab) is an anti-PD-1 monoclonal antibody. It is approved by NMPA for the treatment of recurrent or metastatic triple-negative breast cancer.
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SBP-101 (ivospemin) is a small molecule AMD1/ODC1 inhibitor, being evaluated in combination with gemcitabine & nab-paclitaxel for the treatment of metastatic pancreatic ductal adenocarcinoma.
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Truqap (capivasertib) is a first-in-class, potent, ATP-competitive inhibitor of AKT1/2/3. It is being evaluated for the treatment of locally advanced or metastatic triple-negative breast cancer.