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    [{"orgOrder":0,"company":"CervoMed","sponsor":"CervoMed","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Merger","leadProduct":"Neflamapimod","moa":"MAPK\/p38 alpha","graph1":"Neurology","graph2":"Phase II","graph3":"CervoMed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"CervoMed \/ CervoMed","highestDevelopmentStatusID":"8","companyTruncated":"CervoMed \/ CervoMed"},{"orgOrder":0,"company":"CervoMed","sponsor":"EIP Pharma","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Merger","leadProduct":"Neflamapimod","moa":"MAPK\/p38 alpha","graph1":"Neurology","graph2":"Phase II","graph3":"CervoMed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"CervoMed \/ EIP Pharma","highestDevelopmentStatusID":"8","companyTruncated":"CervoMed \/ EIP Pharma"},{"orgOrder":0,"company":"CervoMed","sponsor":"RA Capital Management","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Private Placement","leadProduct":"Neflamapimod","moa":"MAPK\/p38 alpha","graph1":"Neurology","graph2":"Phase II","graph3":"CervoMed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"CervoMed \/ RA Capital Management","highestDevelopmentStatusID":"8","companyTruncated":"CervoMed \/ RA Capital Management"},{"orgOrder":0,"company":"CervoMed","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Neflamapimod","moa":"MAPK\/p38 alpha","graph1":"Neurology","graph2":"Phase II","graph3":"CervoMed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"CervoMed \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"CervoMed \/ Inapplicable"},{"orgOrder":0,"company":"CervoMed","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Neflamapimod","moa":"MAPK\/p38 alpha","graph1":"Neurology","graph2":"Phase II","graph3":"CervoMed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"CervoMed \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"CervoMed \/ Inapplicable"},{"orgOrder":0,"company":"CervoMed","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Neflamapimod","moa":"MAPK\/p38 alpha","graph1":"Neurology","graph2":"Phase II","graph3":"CervoMed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"CervoMed \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"CervoMed \/ Inapplicable"},{"orgOrder":0,"company":"CervoMed","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Neflamapimod","moa":"MAPK\/p38 alpha","graph1":"Neurology","graph2":"Phase II","graph3":"CervoMed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"CervoMed \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"CervoMed \/ Inapplicable"},{"orgOrder":0,"company":"CervoMed","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Neflamapimod","moa":"MAPK\/p38 alpha","graph1":"Neurology","graph2":"Phase II","graph3":"CervoMed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"CervoMed \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"CervoMed \/ Inapplicable"},{"orgOrder":0,"company":"CervoMed","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Neflamapimod","moa":"MAPK\/p38 alpha","graph1":"Neurology","graph2":"Phase II","graph3":"CervoMed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"CervoMed \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"CervoMed \/ Inapplicable"},{"orgOrder":0,"company":"CervoMed","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Neflamapimod","moa":"MAPK\/p38 alpha","graph1":"Neurology","graph2":"Phase II","graph3":"CervoMed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"CervoMed \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"CervoMed \/ Inapplicable"},{"orgOrder":0,"company":"CervoMed","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Neflamapimod","moa":"MAPK\/p38 alpha","graph1":"Neurology","graph2":"Preclinical","graph3":"CervoMed","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"CervoMed \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"CervoMed \/ Inapplicable"},{"orgOrder":0,"company":"CervoMed","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2025","type":"Inapplicable","leadProduct":"Neflamapimod","moa":"MAPK\/p38 alpha","graph1":"Neurology","graph2":"Phase II","graph3":"CervoMed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"CervoMed \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"CervoMed \/ Inapplicable"},{"orgOrder":0,"company":"CervoMed","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Neflamapimod","moa":"MAPK\/p38 alpha","graph1":"Neurology","graph2":"Phase II","graph3":"CervoMed","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"CervoMed \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"CervoMed \/ Inapplicable"}]

    Find Clinical Drug Pipeline Developments & Deals for Neflamapimod

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                            01

                            CervoMed

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                            CervoMed

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                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CervoMed Reports Positive Phase 2b Neflamapimod Data in Lewy Body Dementia

                            Details : VX-745 (neflamapimod), an investigational orally administered small molecule brain penetrant that inhibits p38MAP kinase alpha. It is being evaluated for the treatment of dementia with lewy bodies.

                            Product Name : VX-745

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 10, 2025

                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            CervoMed

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                            Peptide-Based Therapeutics Summit
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                            CervoMed

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                            Peptide-Based Therapeutics Summit
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                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CervoMed Announces Topline Data from RewinD-LB Phase 2b Trial in Dementia with Lewy Bodies

                            Details : VX-745 (neflamapimod), an investigational orally administered small molecule brain penetrant that inhibits p38MAP kinase alpha. It is being evaluated for the treatment of dementia with lewy bodies.

                            Product Name : VX-745

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 10, 2024

                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            CervoMed

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                            Peptide-Based Therapeutics Summit
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                            CervoMed

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                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CervoMed Announces Orphan Drug Designation for Neflamapimod for Frontotemporal Dementia

                            Details : VX-745 (neflamapimod), an investigational orally administered small molecule brain penetrant that inhibits p38MAP kinase alpha. It is being evaluated for the treatment of frontotemporal dementia.

                            Product Name : VX-745

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 27, 2024

                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            CervoMed

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                            Peptide-Based Therapeutics Summit
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                            CervoMed

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                            Peptide-Based Therapeutics Summit
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                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CervoMed Completes Enrollment in Phase 2b Trial of Neflamapimod for Dementia

                            Details : VX-745 (neflamapimod), an investigational orally administered small molecule brain penetrant that inhibits p38MAP kinase alpha. It is being evaluated for the treatment of dementia with lewy bodies.

                            Product Name : VX-745

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            November 06, 2024

                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            CervoMed

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                            Peptide-Based Therapeutics Summit
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                            CervoMed

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                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CervoMed Completes Phase 2b RewinD-LB Trial of Neflamapimod in DLB

                            Details : VX-745 (neflamapimod), an investigational orally administered small molecule brain penetrant that inhibits p38MAP kinase alpha. It is being evaluated for the treatment of dementia with lewy bodies.

                            Product Name : VX-745

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 15, 2024

                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            CervoMed

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                            Peptide-Based Therapeutics Summit
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                            CervoMed

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                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : RA Capital Management

                            Deal Size : $149.4 million

                            Deal Type : Private Placement

                            DEALS_DEV arrow-down

                            CervoMed Announces $149.4 Million Private Placement Financing with Investors

                            Details : The company intends to use net proceeds for research and development of VX-745 (neflamapimod), an orally administered small molecule inhibiting p38MAP kinase alpha.

                            Product Name : VX-745

                            Product Type : Other Small Molecule

                            Upfront Cash : $50.0 million

                            March 28, 2024

                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : RA Capital Management

                            Deal Size : $149.4 million

                            Deal Type : Private Placement

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                            07

                            CervoMed

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                            Peptide-Based Therapeutics Summit
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                            CervoMed

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                            Peptide-Based Therapeutics Summit
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                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : EIP Pharma

                            Deal Size : Undisclosed

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            CervoMed Announces Completion of Merger with EIP Pharma

                            Details : The Combined company will pursue late-stage clinical development of oral VX-745 (neflamapimod), a small molecule brain penetrant that inhibits p38MAP kinase alpha (p38a), for the treatment of dementia with Lewy bodies.

                            Product Name : VX-745

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            August 16, 2023

                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : EIP Pharma

                            Deal Size : Undisclosed

                            Deal Type : Merger

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                            08

                            CervoMed

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                            Peptide-Based Therapeutics Summit
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                            CervoMed

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                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EIP Pharma Announces First Patient Dosed in RewinD-LB Phase 2b Clinical Trial Evaluating Neflamapimod in Demen...

                            Details : VX-745 (neflamapimod) is an investigational drug that is an orally administered small molecule brain penetrant that inhibits p38MAP kinase alpha, which is investigated for the treatment of dementia with lewy bodies.

                            Product Name : VX-745

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 14, 2023

                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            CervoMed

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                            Peptide-Based Therapeutics Summit
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                            CervoMed

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                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : CervoMed

                            Deal Size : $19.0 million

                            Deal Type : Merger

                            DEALS_DEV arrow-down

                            EIP Pharma and Diffusion Pharmaceuticals Announce Merger Agreement to Create Leading CNS-focused Company Treat...

                            Details : The Combined company will pursue late-stage clinical development of oral neflamapimod, a small molecule brain penetrant that inhibits p38MAP kinase alpha (p38a), for the treatment of dementia with Lewy bodies.

                            Product Name : VX-745

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 30, 2023

                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : CervoMed

                            Deal Size : $19.0 million

                            Deal Type : Merger

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                            10

                            CervoMed

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                            Peptide-Based Therapeutics Summit
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                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EIP Pharma Publishes Translational Data of Preclinical and Phase 2a Results for Neflamapimod in Dementia with ...

                            Details : Neflamapimod (VX-745) is an investigational oral, brain-penetrating small molecule drug that inhibits the intra-cellular enzyme p38MAP kinase alpha (p38α which is expressed in neurons under conditions of stress and disease.

                            Product Name : VX-745

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 21, 2022

                            Lead Product(s) : Neflamapimod

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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