Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Abiraterone Acetate,Prednisolone
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Abiraterone and the combination product Abiraterone/Prednisolone are used to treat men with prostate cancer. The 500 mg (mono product) and 500 mg + 5 mg (combination product) tablets will be marketed in Europe by our partners.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 17, 2022
Lead Product(s) : Abiraterone Acetate,Prednisolone
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : DTX401,Prednisolone
Therapeutic Area : Genetic Disease
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Ultragenyx Reports Positive Results from Phase 3 DTX401 Gene Therapy Study
Details : DTX401 is an investigational AAV8 gene therapy designed to deliver G6Pase-α in patients with Glycogen Storage Disease Type Ia.
Brand Name : DTX401
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
May 30, 2024
Lead Product(s) : DTX401,Prednisolone
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : SPI-62,Prednisolone
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : SPI-62 is Sparrow’s potent and selective investigational HSD-1 inhibitor, which is investigated in combination with prednisolone for the treatment of polymyalgia rheumatica (PMR) to include a third cohort.
Brand Name : SPI-47
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 12, 2023
Lead Product(s) : SPI-62,Prednisolone
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : SPI-62,Prednisolone
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : SPI-47 combines HSD-1 inhibitor, SPI-62, with an effective glucocorticoid medicine, prednisolone. While prednisolone serves to relieve pain and inflammation, SPI-62 lowers active steroid levels within vital organs, and thereby mitigate the side effects o...
Brand Name : SPI-47
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 08, 2023
Lead Product(s) : SPI-62,Prednisolone
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : SPI-62,Prednisolone
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : SPI-47 combines SPI-62 with an efficacious glucocorticoid medicine to potentially relieve debilitating inflammation with fewer side effects,aims to achieve the same efficacy of glucocorticoids while mitigating their associated toxicities.
Brand Name : SPI-47
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 09, 2022
Lead Product(s) : SPI-62,Prednisolone
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : SPI-62,Prednisolone
Therapeutic Area : Musculoskeletal
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : SPI-47 (SPI-62) prevented several CORT adverse effects, demonstrating that by blocking local intracellular glucocorticoid activation with a HSD-1 inhibitor in target tissues, it can mitigate glucocorticoid toxicity.
Brand Name : SPI-47
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 04, 2022
Lead Product(s) : SPI-62,Prednisolone
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Olaparib,Abiraterone Acetate,Prednisolone
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : AstraZeneca
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Positive results from Phase 3 PROpel trial showed LYNPARZA in combination with abiraterone plus prednisone demonstrated a statistically significant and clinically meaningful improvement in rPFS, versus abiraterone plus prednisone for treatment of patient...
Brand Name : Lynparza
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 14, 2022
Lead Product(s) : Olaparib,Abiraterone Acetate,Prednisolone
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : AstraZeneca
Deal Size : Not Applicable
Deal Type : Not Applicable
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