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    [{"orgOrder":0,"company":"NeoTX Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"ISRAEL","productType":"Large molecule","year":"2020","type":"Series C Financing","leadProduct":"Durvalumab","moa":"Trophoblast glycoprotein","graph1":"Oncology","graph2":"Phase I","graph3":"NeoTX Therapeutics","amount2":0.050000000000000003,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.050000000000000003,"dosageForm":"","sponsorNew":"NeoTX Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"NeoTX Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"NeoTX Therapeutics","sponsor":"Active Biotech","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2020","type":"Licensing Agreement","leadProduct":"Durvalumab","moa":"Trophoblast glycoprotein","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"NeoTX Therapeutics","amount2":0.070000000000000007,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0.070000000000000007,"dosageForm":"Intravenous Injection","sponsorNew":"NeoTX Therapeutics \/ Neotx","highestDevelopmentStatusID":"7","companyTruncated":"NeoTX Therapeutics \/ Neotx"},{"orgOrder":0,"company":"NeoTX Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2021","type":"Not Applicable","leadProduct":"Durvalumab","moa":"Trophoblast glycoprotein","graph1":"Oncology","graph2":"Phase I","graph3":"NeoTX Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"NeoTX Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"NeoTX Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"NeoTX Therapeutics","sponsor":"Active Biotech","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2021","type":"Not Applicable","leadProduct":"Durvalumab","moa":"5T4","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"NeoTX Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"NeoTX Therapeutics \/ NeoTX therapeutics","highestDevelopmentStatusID":"7","companyTruncated":"NeoTX Therapeutics \/ NeoTX therapeutics"},{"orgOrder":0,"company":"NeoTX Therapeutics","sponsor":"Active Biotech","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2021","type":"Not Applicable","leadProduct":"Durvalumab","moa":"Trophoblast glycoprotein","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"NeoTX Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"NeoTX Therapeutics \/ NeoTX","highestDevelopmentStatusID":"7","companyTruncated":"NeoTX Therapeutics \/ NeoTX"},{"orgOrder":0,"company":"NeoTX Therapeutics","sponsor":"Translational Drug Development","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"Docetaxel","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"NeoTX Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Injectable\/Injection","sponsorNew":"NeoTX Therapeutics \/ Translational Drug Development","highestDevelopmentStatusID":"8","companyTruncated":"NeoTX Therapeutics \/ Translational Drug Development"}]

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                            01

                            NeoTX Therapeutics

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                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab Estafenatox,Docetaxel,Obinutuzumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Translational Drug Development

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Neotx Announces Successful First Stage Completion of Its Phase 2a Clinical Trial of Naptumomab Estafenatox (Na...

                            Details : Naptumomab estafenatox (NAP; ABR-217620) is a recombinant fusion protein consisting of a chimeric staphylococcal enterotoxin A/E (SEA/SEE) superantigen with several additional substitutions that is linked to a Fab moiety recognizing a tumor-associated gl...

                            Brand Name : ABR-217620

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 01, 2022

                            Lead Product(s) : Naptumomab Estafenatox,Docetaxel,Obinutuzumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Translational Drug Development

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            NeoTX Therapeutics

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                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Active Biotech

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Data on Naptumomab Estafenatox Enhancing CAR-T Cells Potency Presented by Active Biotech’s Partner NeoTX at ...

                            Details : Naptumomab estafenatox (NAP) is a cell therapy candidate, currently in Phase I. It is in clinical development for advanced solid tumors utilizing its proprietary Tumor Targeted Superantigen platform.

                            Brand Name : ABR-217620

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            November 30, 2021

                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Active Biotech

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Recipient : Active Biotech

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Active Biotech Provides Status Update of its Clinical Naptumomab Project

                            Details : The study was amended to also include assessment of pre-treatment with obinutuzumab to assess its effect on anti-drug antibodies (ADAs) to naptumomab.

                            Brand Name : NAP

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            July 05, 2021

                            Lead Product(s) : Naptumomab Estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Recipient : Active Biotech

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            US FDA Clears NeoTX’s IND Application for Phase 2 Trial of Naptumomab Estafenatox to Treat Solid Tumors

                            Details : Naptumomab Estafenatox, the company’s lead TTS molecule, binds a genetically engineered bacterial determinant to the tumor surface while simultaneously activating and expanding tumor specific immune cells.

                            Brand Name : NAP

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 19, 2021

                            Lead Product(s) : Naptumomab estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            NeoTX Therapeutics

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                            Lead Product(s) : Naptumomab estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Active Biotech

                            Deal Size : $71.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Active Biotech Receive Milestone Payment From Neotx

                            Details : In 2016, Active Biotech and NeoTX entered into a partnership for the development and commercialization of naptumomab in cancer indications.

                            Brand Name : ABR-217620

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            December 11, 2020

                            Lead Product(s) : Naptumomab estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Active Biotech

                            Deal Size : $71.0 million

                            Deal Type : Licensing Agreement

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                            Lead Product(s) : Naptumomab estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : $45.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Israeli biotech NeoTX lands $45M series C for combo I-O cancer trials

                            Details : The company plans to complete the dose escalation phase of the Phase 1b trial of naptumomab estafenatox in combination with durvalumab and continue to develop our patented STR platform.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            February 19, 2020

                            Lead Product(s) : Naptumomab estafenatox,Durvalumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : $45.0 million

                            Deal Type : Series C Financing

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