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III","graph3":"ProKidney","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Percutaneous Injection","sponsorNew":"ProKidney \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"ProKidney \/ Inapplicable"},{"orgOrder":0,"company":"ProKidney","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Rilparencel","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase III","graph3":"ProKidney","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Percutaneous Injection","sponsorNew":"ProKidney \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"ProKidney \/ Inapplicable"},{"orgOrder":0,"company":"ProKidney","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Rilparencel","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase III","graph3":"ProKidney","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Percutaneous Injection","sponsorNew":"ProKidney \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"ProKidney \/ Inapplicable"},{"orgOrder":0,"company":"ProKidney","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Rilparencel","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase III","graph3":"ProKidney","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Percutaneous Injection","sponsorNew":"ProKidney \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"ProKidney \/ Inapplicable"},{"orgOrder":0,"company":"ProKidney","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Rilparencel","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase III","graph3":"ProKidney","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Percutaneous Injection","sponsorNew":"ProKidney \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"ProKidney \/ Inapplicable"},{"orgOrder":0,"company":"ProKidney","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Rilparencel","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase III","graph3":"ProKidney","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Percutaneous Injection","sponsorNew":"ProKidney \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"ProKidney \/ Inapplicable"},{"orgOrder":0,"company":"ProKidney","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Rilparencel","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase III","graph3":"ProKidney","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Percutaneous Injection","sponsorNew":"ProKidney \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"ProKidney \/ Inapplicable"},{"orgOrder":0,"company":"ProKidney","sponsor":"Jefferies","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Public Offering","leadProduct":"Rilparencel","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase III","graph3":"ProKidney","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Percutaneous Injection","sponsorNew":"ProKidney \/ Jefferies","highestDevelopmentStatusID":"10","companyTruncated":"ProKidney \/ Jefferies"},{"orgOrder":0,"company":"ProKidney","sponsor":"Jefferies","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Public Offering","leadProduct":"Rilparencel","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase III","graph3":"ProKidney","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Percutaneous Injection","sponsorNew":"ProKidney \/ Jefferies","highestDevelopmentStatusID":"10","companyTruncated":"ProKidney \/ Jefferies"},{"orgOrder":0,"company":"ProKidney","sponsor":"Jefferies","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Public Offering","leadProduct":"Rilparencel","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase III","graph3":"ProKidney","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Percutaneous Injection","sponsorNew":"ProKidney \/ Jefferies","highestDevelopmentStatusID":"10","companyTruncated":"ProKidney \/ Jefferies"},{"orgOrder":0,"company":"ProKidney","sponsor":"Social Capital Suvretta Holdings Corp. III","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Merger","leadProduct":"Rilparencel","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase III","graph3":"ProKidney","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Percutaneous Injection","sponsorNew":"ProKidney \/ Social Capital Suvretta Holdings Corp. III","highestDevelopmentStatusID":"10","companyTruncated":"ProKidney \/ Social Capital Suvretta Holdings Corp. III"},{"orgOrder":0,"company":"Vascular Therapies","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Antibiotic","year":"2024","type":"Inapplicable","leadProduct":"Sirolimus","moa":"mTOR","graph1":"Nephrology","graph2":"Phase III","graph3":"Vascular Therapies","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Vascular Therapies \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Vascular Therapies \/ Inapplicable"},{"orgOrder":0,"company":"ProKidney","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Rilparencel","moa":"Undisclosed","graph1":"Nephrology","graph2":"Phase III","graph3":"ProKidney","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"ProKidney \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"ProKidney \/ Inapplicable"}]

    Find Nephrology Drugs in Phase III Clinical Development

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                            01

                            AbbVie Inc

                            U.S.A
                            German Wound Congress
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                            Lead Product(s) : Atrasentan

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Chinook Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Chinook Therapeutics Obtains Worldwide Rights from AbbVie to Atrasentan with Plans to Develop for the Treatmen...

                            Details : Chinook Therapeutics in-license of atrasentan provides a unique opportunity for Chinook to add a potential new drug to its precision medicine portfolio for the treatment of rare CKD conditions.

                            Product Name : CHK-01

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            October 01, 2020

                            Lead Product(s) : Atrasentan

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Chinook Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            02

                            Swedish Orphan Biovitrum AB

                            Sweden arrow
                            German Wound Congress
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                            Swedish Orphan Biovitrum AB

                            Sweden arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Apellis Gets FDA Priority Review for EMPAVELI in C3G & Primary IC-MPGN

                            Details : Aspaveli (pegcetacoplan) is the first and only approved therapy for geographic atrophy. Now it is being evaluated for the treatment of C3 glomerulopathy & IC-MPGN.

                            Product Name : Aspaveli

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            April 01, 2025

                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Otsuka Pharmaceutical

                            Japan arrow
                            German Wound Congress
                            Not Confirmed

                            Otsuka Pharmaceutical

                            Japan arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Sibeprenlimab

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Otsuka Files BLA for Sibeprenlimab in Immunoglobulin A Nephropathy Treatment

                            Details : VIS649 (sibeprenlimab) is an investigational humanized IgG2 monoclonal antibody that reduces Gd-IgA1 by binding to APRIL. It is being developed for Immunoglobulin A Nephropathy.

                            Product Name : VIS649

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 31, 2025

                            Lead Product(s) : Sibeprenlimab

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Genentech

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                            German Wound Congress
                            Not Confirmed

                            Genentech

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                            German Wound Congress
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                            Lead Product(s) : Obinutuzumab,Paracetamol,Diphenhydramine

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Accepts Genentech’s Gazyva sBLA for Lupus Nephritis

                            Details : Gazyva® (obinutuzumab) is a CD20-directed cytolytic antibody, which is currently being evaluated for the treatment of lupus nephritis.

                            Product Name : Gazyva

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            March 05, 2025

                            Lead Product(s) : Obinutuzumab,Paracetamol,Diphenhydramine

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            German Wound Congress
                            Not Confirmed

                            Novartis Pharmaceuticals Corporation

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Iptacopan HCl

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Novartis oral Fabhalta® (iptacopan) Receives Positive CHMP Opinion

                            Details : Fabhalta (iptacopan) is an oral, Factor B inhibitor of the alternative complement pathway. It is being evaluated for the treatment of patients withC3 glomerulopathy.

                            Product Name : Fabhalta

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 28, 2025

                            Lead Product(s) : Iptacopan HCl

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Swedish Orphan Biovitrum AB

                            Sweden arrow
                            German Wound Congress
                            Not Confirmed

                            Swedish Orphan Biovitrum AB

                            Sweden arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Apellis Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            EMA Validates Aspaveli® for C3G and Primary IC-MPGN Treatment

                            Details : Aspaveli (pegcetacoplan) is the first and only approved therapy for geographic atrophy. Now it is being evaluated for the treatment of C3 glomerulopathy & IC-MPGN.

                            Product Name : Aspaveli

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            February 20, 2025

                            Lead Product(s) : Pegcetacoplan

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Apellis Pharmaceuticals

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Travere Therapeutics

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                            German Wound Congress
                            Not Confirmed

                            Travere Therapeutics

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Sparsentan

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Travere Therapeutics to Submit sNDA for FILSPARI® (sparsentan) in FSGS

                            Details : Filspari (sparsentan) is an oral drug designed to selectively target two critical pathways - endothelin-1 and angiotensin II. It is approved for the treatment of focal segmental glomerulosclerosis.

                            Product Name : Filspari

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 11, 2025

                            Lead Product(s) : Sparsentan

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            KORU Medical Systems

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            KORU Medical Systems

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            KORU Medical Joins Phase III Clinical Trial for Nephrology Drug Indication

                            Details : The collaboration aims to conduct Phase III clinical trial for an expanded indication of a commercialized drug therapy. The expanded indication is intended to treat a rare renal disorder.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            January 30, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Undisclosed

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            09

                            Novo Nordisk

                            Denmark arrow
                            German Wound Congress
                            Not Confirmed

                            Novo Nordisk

                            Denmark arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Semaglutide

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            US FDA Approves Novo Nordisk's Ozempic to Cut Risk of Diabetic Kidney Disease Progression

                            Details : FDA has approved Ozempic (GLP-1 receptor agonists) to reduce the risk of kidney disease worsening, kidney failure, and death due to cardiovascular disease in adults with type 2 diabetes and CKD.

                            Product Name : Ozempic

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            January 28, 2025

                            Lead Product(s) : Semaglutide

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Vertex Pharmaceuticals

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                            German Wound Congress
                            Not Confirmed

                            Vertex Pharmaceuticals

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Povetacicept

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Zai Lab

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Vertex, Zai Lab Partner to Treat Autoimmune Diseases in Asia-Pacific

                            Details : Through the collaboration, Zai Lab will be responsible for all development and commercialization activities in the licensed territory once pove (povetacicept) becomes an approved product.

                            Product Name : Pove

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            January 10, 2025

                            Lead Product(s) : Povetacicept

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Zai Lab

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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