Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Navacaprant
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Neumora Reports KOASTAL-1 Data for Navacaprant in Major Depression
Details : NMRA-140 (navacaprant) is a highly selective, novel kappa opioid receptor (KOR) antagonist being developed as a potential monotherapy treatment for major depressive disorder.
Product Name : NMRA-140
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 02, 2025
Lead Product(s) : Navacaprant
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Neumora Starts Phase 1b Study of NMRA-511 for Alzheimer's Agitation
Details : NMRA-511 is an oral potent and selective, best-in-class investigational V1aR antagonist, being investigated for the treatment of agitation associated with dementia due to Alzheimer’s disease.
Product Name : NMRA-511
Product Type : Small molecule
Upfront Cash : Not Applicable
June 20, 2024
Lead Product(s) : Navacaprant
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Neumora Announces Initiation of Ph 2 Study of Navacaprant in Bipolar Depression
Details : NMRA-140 (navacaprant) is a highly selective, novel kappa opioid receptor (KOR) antagonist being developed as a potential monotherapy treatment for bipolar depression.
Product Name : NMRA-140
Product Type : Small molecule
Upfront Cash : Not Applicable
May 14, 2024
Lead Product(s) : Navacaprant
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NMRA-266
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Neumora Therapeutics Announces Clinical Hold of Phase 1 NMRA-266 Study
Details : Neumora's investigation product NMRA-266 is a positive allosteric modulator of the M4 muscarinic receptor. It is being evaluated in the clinical trials for the treatment of Schizophrenia.
Product Name : NMRA-266
Product Type : Small molecule
Upfront Cash : Not Applicable
April 15, 2024
Lead Product(s) : NMRA-266
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NMRA-266
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Neumora Therapeutics Announces NMRA-266 IND Clearance and Initiation of Phase 1 Clinical Study
Details : NMRA-266 is a highly selective positive allosteric modulator of the M4 muscarinic receptor, a clinically validated target for the treatment of schizophrenia.
Product Name : NMRA-266
Product Type : Small molecule
Upfront Cash : Not Applicable
November 27, 2023
Lead Product(s) : NMRA-266
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Navacaprant
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : BlackThorn Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NMRA-140 (navacaprant) is a highly selective, novel kappa opioid receptor (KOR) antagonist being developed as a potential monotherapy treatment for MDD.
Product Name : NMRA-140
Product Type : Small molecule
Upfront Cash : Not Applicable
July 18, 2023
Lead Product(s) : Navacaprant
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : BlackThorn Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Navacaprant
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Abu Dhabi Growth Fund
Deal Size : $112.0 million
Deal Type : Series B Financing
Neumora Therapeutics Announces $112 Million Series B Financing
Details : The funding will support the advancement of a broad clinical and preclinical pipeline of novel precision medicine candidates including BTRX-335140 (NMRA-140) for neuropsychiatric disorders and neurodegenerative diseases and the development of precision n...
Product Name : BTRX-335140
Product Type : Small molecule
Upfront Cash : Undisclosed
October 11, 2022
Lead Product(s) : Navacaprant
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Abu Dhabi Growth Fund
Deal Size : $112.0 million
Deal Type : Series B Financing
Lead Product(s) : Undisclosed
Therapeutic Area : Psychiatry/Psychology
Study Phase : Preclinical
Sponsor : Vanderbilt University
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : The research collaboration will support ongoing preclinical work at WCNDD to advance backup series of highly selective M4 receptor PAMs. Neumora is progressing the lead series toward the nomination of a development candidate.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
February 17, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Preclinical
Sponsor : Vanderbilt University
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Psychiatry/Psychology
Study Phase : Discovery
Sponsor : Amgen Inc
Deal Size : $100.0 million
Deal Type : Collaboration
Neumora Therapeutics Launches to Pioneer a New Era of Precision Medicines for Brain Diseases
Details : Through the advancement of data science tools and biopsies, the field progressed to understand that these were diseases driven by biological mechanisms and genetics.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
October 07, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Discovery
Sponsor : Amgen Inc
Deal Size : $100.0 million
Deal Type : Collaboration