[{"orgOrder":0,"company":"Neuraly","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Peptide","year":"2020","type":"Not Applicable","leadProduct":"NLY01","moa":"GLP1 receptor","graph1":"Neurology","graph2":"Phase II","graph3":"Neuraly","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Neuraly \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Neuraly \/ Not Applicable"},{"orgOrder":0,"company":"Neuraly","sponsor":"Neuraly","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Peptide","year":"2020","type":"Agreement","leadProduct":"NLY01","moa":"GLP-1 receptor","graph1":"Ophthalmology","graph2":"Preclinical","graph3":"Neuraly","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"","sponsorNew":"Neuraly \/ Neuraly","highestDevelopmentStatusID":"4","companyTruncated":"Neuraly \/ Neuraly"},{"orgOrder":0,"company":"Neuraly","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Peptide","year":"2022","type":"Not Applicable","leadProduct":"NLY01","moa":"GLP1 receptor","graph1":"Neurology","graph2":"Phase II","graph3":"Neuraly","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Neuraly \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Neuraly \/ Not Applicable"},{"orgOrder":0,"company":"Neuraly","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Peptide","year":"2023","type":"Not Applicable","leadProduct":"Exenatide","moa":"","graph1":"Neurology","graph2":"Phase II","graph3":"Neuraly","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Neuraly \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Neuraly \/ Not Applicable"}]

Find Clinical Drug Pipeline Developments & Deals by Neuraly

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : NLY01 is a proprietary long-acting analogue of exendin-4, a glucagon-like peptide-1 receptor (GLP-1R) agonist that slows progression in animal models of parkinson’s and alzheimer’s disease.

                          Brand Name : NLY01

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          March 27, 2023

                          Lead Product(s) : Exenatide

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : NLY01, Neuraly’s lead development asset, is a glucagon-like peptide 1 receptor agonist that has been demonstrated to inhibit pathological activation of microglia by binding upregulated GLP-1R in animal models of neurodegenerative diseases such as PD.

                          Brand Name : NLY01

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          April 19, 2022

                          Lead Product(s) : NLY01

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : Preclinical study in glaucoma, in combination with Neuraly’s clinical trials assessing NLY01 in Parkinson’s and Alzheimer’s reflects the growing evidence that NLY01 can deliver a neuroprotective effect across a number of challenging diseases.

                          Brand Name : NLY01

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          November 10, 2020

                          Lead Product(s) : NLY01

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Preclinical

                          Recipient : University of Pennsylvania

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          04

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : Novel mechanism of action inhibits pathological activation of microglial cells and prevents neuronal cell death.

                          Brand Name : Undisclosed

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          March 03, 2020

                          Lead Product(s) : NLY01

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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