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    [{"orgOrder":0,"company":"Neurimmune","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Cardiology\/Vascular Diseases","country":"SWITZERLAND","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"NI006","moa":"Transthyretin amyloid","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase I","graph3":"Neurimmune","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0,"dosageForm":"","sponsorNew":"Neurimmune \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Neurimmune \/ Not Applicable"},{"orgOrder":0,"company":"Neurimmune","sponsor":"Ethris","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"GERMANY","productType":"Large molecule","year":"2020","type":"Collaboration","leadProduct":"NI007","moa":"","graph1":"Infections and Infectious Diseases","graph2":"Discovery","graph3":"Neurimmune","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"Neurimmune \/ Neurimmune","highestDevelopmentStatusID":"2","companyTruncated":"Neurimmune \/ Neurimmune"},{"orgOrder":0,"company":"Neurimmune","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2021","type":"Not Applicable","leadProduct":"Aducanumab","moa":"Amyloid beta aggregation","graph1":"Neurology","graph2":"Approved","graph3":"Neurimmune","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Neurimmune \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Neurimmune \/ Not Applicable"},{"orgOrder":0,"company":"Neurimmune","sponsor":"Ono Pharmaceutical","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2022","type":"Collaboration","leadProduct":"Human-derived Monoclonal Antibodies","moa":"","graph1":"Neurology","graph2":"Discovery Platform","graph3":"Neurimmune","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Neurimmune \/ Ono Pharmaceutical","highestDevelopmentStatusID":"3","companyTruncated":"Neurimmune \/ Ono Pharmaceutical"},{"orgOrder":0,"company":"Neurimmune","sponsor":"Alexion Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"","productType":"Large molecule","year":"2022","type":"Collaboration","leadProduct":"NI006","moa":"Transthyretin amyloid","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase I","graph3":"Neurimmune","amount2":0.76000000000000001,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0.76000000000000001,"dosageForm":"Infusion","sponsorNew":"Neurimmune \/ Alexion","highestDevelopmentStatusID":"6","companyTruncated":"Neurimmune \/ Alexion"},{"orgOrder":0,"company":"Neurimmune","sponsor":"Alexion Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Cardiology\/Vascular Diseases","country":"SWITZERLAND","productType":"Large molecule","year":"2022","type":"Collaboration","leadProduct":"NI006","moa":"Transthyretin amyloid","graph1":"Cardiology\/Vascular Diseases","graph2":"Phase I","graph3":"Neurimmune","amount2":0.76000000000000001,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Cardiovascular Diseases","amount2New":0.76000000000000001,"dosageForm":"Infusion","sponsorNew":"Neurimmune \/ Alexion Pharmaceuticals","highestDevelopmentStatusID":"6","companyTruncated":"Neurimmune \/ Alexion Pharmaceuticals"},{"orgOrder":0,"company":"Neurimmune","sponsor":"Biogen","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"","productType":"Large molecule","year":"2024","type":"Termination","leadProduct":"Aducanumab","moa":"","graph1":"Neurology","graph2":"Approved","graph3":"Neurimmune","amount2":0.38,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0.38,"dosageForm":"Infusion","sponsorNew":"Neurimmune \/ Biogen","highestDevelopmentStatusID":"12","companyTruncated":"Neurimmune \/ Biogen"}]

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                            01

                            Neurimmune

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                            Lead Product(s) : Aducanumab

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Biogen

                            Deal Size : $380.0 million

                            Deal Type : Termination

                            DEALS_DEV arrow-down

                            Neurimmune Regains Global Rights to Brain Amyloid Depleter for Alzheimer’s Treatment

                            Details : Under the termination, Neurimmune regained global rights to aducanumab, a recombinant human antibody developed to deplete brain amyloid, for the treatment and prevention of Alzheimer’s disease.

                            Brand Name : BIIB037

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            January 31, 2024

                            Lead Product(s) : Aducanumab

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Biogen

                            Deal Size : $380.0 million

                            Deal Type : Termination

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                            02

                            Neurimmune

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                            euroPLX 86 Munich
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                            Lead Product(s) : NI006

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase I

                            Sponsor : Alexion Pharmaceuticals

                            Deal Size : $760.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            AstraZeneca and Neurimmune Close Exclusive Global Collaboration and Licence Agreement to Develop and Commercia...

                            Details : NI006 adds a novel and complementary approach to AstraZeneca and Alexion’s pipeline of investigational therapies focused on amyloidosis and strengthens the Company’s broader commitment to addressing cardiomyopathies that can lead to heart failure (HF...

                            Brand Name : NI006

                            Molecule Type : Large molecule

                            Upfront Cash : $30.0 million

                            March 01, 2022

                            Lead Product(s) : NI006

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase I

                            Sponsor : Alexion Pharmaceuticals

                            Deal Size : $760.0 million

                            Deal Type : Collaboration

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                            03

                            Neurimmune

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                            Lead Product(s) : Human-derived Monoclonal Antibodies

                            Therapeutic Area : Neurology

                            Study Phase : Discovery Platform

                            Sponsor : Ono Pharmaceutical

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Ono Expands Drug Discovery Collaboration with Neurimmune AG in the Field of Neurodegenerative Diseases

                            Details : In the new collaboration, companies aim to generate and validate human-derived monoclonal antibodies (NI504) against Ono’s selected drug targets. Ono will obtain exclusive rights for worldwide development and commercialization of antibody products resu...

                            Brand Name : NI504

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            January 17, 2022

                            Lead Product(s) : Human-derived Monoclonal Antibodies

                            Therapeutic Area : Neurology

                            Highest Development Status : Discovery Platform

                            Sponsor : Ono Pharmaceutical

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            04

                            Neurimmune

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                            Lead Product(s) : NI006

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase I

                            Sponsor : Alexion Pharmaceuticals

                            Deal Size : $760.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            AstraZeneca and Neurimmune Sign Exclusive Global Collaboration and Licence Agreement to Develop and Commercial...

                            Details : Under the agreement, Alexion will be granted an exclusive worldwide licence to develop, manufacture and commercialise NI006. NI006, an ATTR depleter, a novel and complementary approach to AstraZeneca and Alexion’s pipeline of investigational therapies ...

                            Brand Name : NI006

                            Molecule Type : Large molecule

                            Upfront Cash : $30.0 million

                            January 07, 2022

                            Lead Product(s) : NI006

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase I

                            Sponsor : Alexion Pharmaceuticals

                            Deal Size : $760.0 million

                            Deal Type : Collaboration

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                            05

                            Neurimmune

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                            Lead Product(s) : Aducanumab

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            FDA Approval of Aducanumab

                            Details : The data of three separate clinical studies unequivocally show that aducanumab’s biological activity removed amyloid from brains of patients with Alzheimer’s disease.

                            Brand Name : Aduhelm

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 07, 2021

                            Lead Product(s) : Aducanumab

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Neurimmune

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                            Lead Product(s) : NI007

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Discovery

                            Recipient : Ethris

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Neurimmune and Ethris Enter Collaboration to Rapidly Develop Inhaled mRNA-based Antibody Therapy for COVID-19

                            Details : Under the collaboration agreement, Neurimmune and Ethris will jointly conduct research and development activities while sharing costs and revenues resulting from the collaboration.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            April 01, 2020

                            Lead Product(s) : NI007

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Discovery

                            Recipient : Ethris

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Neurimmune

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                            Lead Product(s) : NI006

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Neurimmune Announces the Initiation of a Phase 1 Study of NI006 for the Treatment of ATTR Cardiomyopathy

                            Details : Phase 1 clinical trial will evaluate the safety, tolerability, pharmacokinetics and exploratory efficacy of NI006 in patients with wild-type and hereditary forms of ATTR cardiomyopathy.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            February 27, 2020

                            Lead Product(s) : NI006

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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