Lead Product(s) : Fremanezumab
Therapeutic Area : Neurology
Study Phase : Phase IV
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
New AJOVY® (fremanezumab) Migraine Prevention Data Challenges Treatment Pauses
Details : Ajovy (fremanezumab) is a FDA approved, humanized monoclonal antibody which selectively binds the calcitonin gene-related peptide, it is indicated for preventive treatment of migraine in adults.
Brand Name : Ajovy
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 28, 2024
Lead Product(s) : Fremanezumab
Therapeutic Area : Neurology
Highest Development Status : Phase IV
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Elyxyb (celecoxib) is a nonsteroidal anti-inflammatory drug with analgesic, anti-inflammatory, and antipyretic properties. Celecoxib inhibits prostaglandin synthesis, primarily via inhibition of COX-2. It is being developed for migrane pain.
Brand Name : Elyxyb
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 22, 2023
Details : Ajovy (Fremanezumab-vfrm) is a subcutaneous injection of the anti-CGRP (calcitonin gene-related peptide) monoclonal antibody, which is produced by recombinant DNA technology. it's used for patients with chronic and episodic migraine.
Brand Name : Ajovy
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 17, 2023
Details : AJOVY (Fremanezumab-vfrm) is a subcutaneous injection of the anti-CGRP (calcitonin gene-related peptide) monoclonal antibody, which is produced by recombinant DNA technology. it's used for patients with chronic and episodic migraine.
Brand Name : Ajovy
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 30, 2023
Details : Andexxa (andexanet alfa) is a recombinant modified human factor Xa (FXa) protein indicated for patients treated with rivaroxaban or apixaban, when reversal of anticoagulation is needed due to life-threatening or uncontrolled bleeding.
Brand Name : Andexxa
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 05, 2023
Lead Product(s) : Deutetrabenazine
Therapeutic Area : Neurology
Study Phase : Phase IV
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : AUSTEDO (deutetrabenazine) Tablets is first and only vesicular monoamine transporter 2 (VMAT2) inhibitor approved by U.S. Food and Drug Administration in adults for treatment of tardive dyskinesia and for treatment of chorea associated with Huntington’...
Brand Name : Austedo
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 06, 2022
Lead Product(s) : Deutetrabenazine
Therapeutic Area : Neurology
Highest Development Status : Phase IV
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aducanumab
Therapeutic Area : Neurology
Study Phase : Phase IV
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Biogen Submits Final Protocol for ADUHELM® (aducanumab-avwa) Phase 4 ENVISION Trial to FDA
Details : The confirmatory ENVISION trial is a requirement based on FDA’s accelerated approval of ADUHELM® (aducanumab-avwa), a monoclonal antibody directed against amyloid beta, 100 mg/mL injection for intravenous use in early Alzheimer’s disease.
Brand Name : Aduhelm
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 30, 2022
Lead Product(s) : Aducanumab
Therapeutic Area : Neurology
Highest Development Status : Phase IV
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Anjeso (meloxicam) injection, a preferential COX-2 inhibitor that possesses analgesic, anti-inflammatory, and antipyretic activities, which are believed to be related to the inhibition of COX-2 and subsequent reduction in prostaglandin biosynthesis.
Brand Name : Anjeso
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 08, 2022
Lead Product(s) : Cladribine
Therapeutic Area : Neurology
Study Phase : Phase IV
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : New real-world data show MAVENCLAD® (cladribine tablets) had lower annualised relapse rates and longer time to first relapse and time to switch than fingolimod, dimethyl fumarate and teriflunomide in relapsing multiple sclerosis patients.
Brand Name : Mavenclad
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 24, 2022
Lead Product(s) : Cladribine
Therapeutic Area : Neurology
Highest Development Status : Phase IV
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Aducanumab
Therapeutic Area : Neurology
Study Phase : Phase IV
Sponsor : Eisai
Deal Size : Not Applicable
Deal Type : Not Applicable
Update on the Phase 4 ENVISION Confirmatory Study of ADUHELM®
Details : ADUHELM is indicated for the treatment of Alzheimer’s disease. Treatment with ADUHELM should be initiated in patients with mild cognitive impairment or mild dementia stage of disease, the population in which treatment was initiated in clinical trials.
Brand Name : Aduhelm
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 27, 2022
Lead Product(s) : Aducanumab
Therapeutic Area : Neurology
Highest Development Status : Phase IV
Sponsor : Eisai
Deal Size : Not Applicable
Deal Type : Not Applicable
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