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Neuro"},{"orgOrder":0,"company":"Neurona Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"Human Pluripotent Stem Cell Derived Neuronal Cell Therapy","moa":"GABA","graph1":"Neurology","graph2":"Phase I\/ Phase II","graph3":"Neurona Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Intracerebral","sponsorNew":"Neurona Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Neurona Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Neurona Therapeutics","sponsor":"California Institute for Regenerative Medicine","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Funding","leadProduct":"Human Pluripotent Stem Cell Derived Neuronal Cell Therapy","moa":"GABA","graph1":"Neurology","graph2":"Phase I\/ Phase II","graph3":"Neurona Therapeutics","amount2":0.01,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Neurology","amount2New":0.01,"dosageForm":"Intracerebral","sponsorNew":"Neurona Therapeutics \/ California Institute for Regenerative Medicine","highestDevelopmentStatusID":"7","companyTruncated":"Neurona Therapeutics \/ California Institute for Regenerative Medicine"},{"orgOrder":0,"company":"Neurona Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"Human Pluripotent Stem Cell Derived Neuronal Cell Therapy","moa":"GABA","graph1":"Neurology","graph2":"Phase I\/ Phase II","graph3":"Neurona Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph 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Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Neurona Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Neurona Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Neurona Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"Human Pluripotent Stem Cell Derived Neuronal Cell Therapy","moa":"","graph1":"Neurology","graph2":"Phase I\/ Phase II","graph3":"Neurona Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"","sponsorNew":"Neurona Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"7","companyTruncated":"Neurona Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Neurona 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Therapeutics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Neurona Therapeutics \/ CIRM","highestDevelopmentStatusID":"14","companyTruncated":"Neurona Therapeutics \/ CIRM"}]

Find Clinical Drug Pipeline Developments & Deals by Neurona Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The proceeds will support the development of a next generation neural cell therapy candidate, NRTX-1001, comprising GABAergic interneurons for drug-resistant unilateral mesial temporal lobe epilepsy.

                          Brand Name : NRTX-1001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          September 10, 2024

                          Lead Product(s) : NRTX-1001

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : CIRM

                          Deal Size : $3.8 million

                          Deal Type : Funding

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                          02

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : NRTX-1001, comprising GABAergic interneurons is a GABA inhibitor. It is being evaluated for the treatment of drug-resistant mesial temporal lobe epilepsy

                          Brand Name : NRTX-1001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          June 18, 2024

                          Lead Product(s) : NRTX-1001

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Through the financing, Neurona will focus on the development of NRTX-1001 for the treatment of drug-resistant mesial temporal lobe epilepsy and also has potential application in Alzheimer’s disease.

                          Brand Name : NRTX-1001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          February 08, 2024

                          Lead Product(s) : NRTX-1001

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Viking Global Investors

                          Deal Size : $120.0 million

                          Deal Type : Financing

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                          04

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : NRTX-1001 is a regenerative neural cell therapy candidate derived from human pluripotent stem cells. It secretes inhibitory neurotransmitter GABA to repair hyper-excitable neural networks. It is being investigated for dominant hemisphere drug-resistant f...

                          Brand Name : NRTX-1001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          October 19, 2023

                          Lead Product(s) : NRTX-1001

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : NRTX-1001 is a regenerative neural cell therapy candidate derived from human pluripotent stem cells. It secretes inhibitory neurotransmitter GABA to repair hyper-excitable neural networks. It is being investigated for dominant hemisphere drug-resistant f...

                          Brand Name : NRTX-1001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          February 14, 2023

                          Lead Product(s) : NRTX-1001

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy

                          Therapeutic Area : Neurology

                          Study Phase : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Early data from the first two patients treated with NRTX-1001 (Human Pluripotent Stem Cell Derived Neuronal Cell Therapy) report a trend toward seizure suppression and that administration of the cell treatment has been well-tolerated.

                          Brand Name : NRTX-1001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          November 21, 2022

                          Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy

                          Therapeutic Area : Neurology

                          Study Phase : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : The patient received NRTX-1001 (human pluripotent stem cell derived neuronal cell therapy), and the treatment was well tolerated; there have been no serious adverse events. The patient has reported having four seizures during the first three months since...

                          Brand Name : NRTX-1001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          September 21, 2022

                          Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy

                          Therapeutic Area : Neurology

                          Study Phase : Phase I/ Phase II

                          Sponsor : ClearPoint Neuro

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : NRTX-1001 is a regenerative neural cell therapy delivered as a single dose and designed to provide GABA, a key inhibitory neurotransmitter, to repair hyper-excitable neural networks associated with MTLE, the most common form of focal epilepsy in adults.

                          Brand Name : NRTX-1001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          June 29, 2022

                          Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : ClearPoint Neuro

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy

                          Therapeutic Area : Neurology

                          Study Phase : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : NRTX-1001 is a regenerative neural cell therapy delivered as a single dose and designed to provide long-term secretion of gamma-aminobutyric acid (GABA), a key inhibitory neurotransmitter, to repair hyper-excitable neural networks associated with mesial ...

                          Brand Name : NRTX-1001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          June 29, 2022

                          Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy

                          Therapeutic Area : Neurology

                          Study Phase : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : NRTX-1001 (Human Pluripotent Stem Cell Derived Neuronal Cell Therapy) is a regenerative neural cell therapy fully-differentiated neural cells, called interneurons, secrete the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).

                          Brand Name : NRTX-1001

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          June 17, 2022

                          Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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