Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : NRTX-1001
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : CIRM
Deal Size : $3.8 million
Deal Type : Funding
Neurona Therapeutics Receives $3.8M Grant for Neural Cell Therapy Development
Details : The proceeds will support the development of a next generation neural cell therapy candidate, NRTX-1001, comprising GABAergic interneurons for drug-resistant unilateral mesial temporal lobe epilepsy.
Brand Name : NRTX-1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
September 10, 2024
Lead Product(s) : NRTX-1001
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : CIRM
Deal Size : $3.8 million
Deal Type : Funding
Lead Product(s) : NRTX-1001
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Neurona's NRTX-1001 Gets FDA RMAT Designation for Epilepsy
Details : NRTX-1001, comprising GABAergic interneurons is a GABA inhibitor. It is being evaluated for the treatment of drug-resistant mesial temporal lobe epilepsy
Brand Name : NRTX-1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 18, 2024
Lead Product(s) : NRTX-1001
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NRTX-1001
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Viking Global Investors
Deal Size : $120.0 million
Deal Type : Financing
Neurona Raises $120M To Advance Regenerative Cell Therapies For Neurological Disorders
Details : Through the financing, Neurona will focus on the development of NRTX-1001 for the treatment of drug-resistant mesial temporal lobe epilepsy and also has potential application in Alzheimer’s disease.
Brand Name : NRTX-1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
February 08, 2024
Lead Product(s) : NRTX-1001
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Viking Global Investors
Deal Size : $120.0 million
Deal Type : Financing
Lead Product(s) : NRTX-1001
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NRTX-1001 is a regenerative neural cell therapy candidate derived from human pluripotent stem cells. It secretes inhibitory neurotransmitter GABA to repair hyper-excitable neural networks. It is being investigated for dominant hemisphere drug-resistant f...
Brand Name : NRTX-1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
October 19, 2023
Lead Product(s) : NRTX-1001
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NRTX-1001
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NRTX-1001 is a regenerative neural cell therapy candidate derived from human pluripotent stem cells. It secretes inhibitory neurotransmitter GABA to repair hyper-excitable neural networks. It is being investigated for dominant hemisphere drug-resistant f...
Brand Name : NRTX-1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
February 14, 2023
Lead Product(s) : NRTX-1001
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Early data from the first two patients treated with NRTX-1001 (Human Pluripotent Stem Cell Derived Neuronal Cell Therapy) report a trend toward seizure suppression and that administration of the cell treatment has been well-tolerated.
Brand Name : NRTX-1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 21, 2022
Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The patient received NRTX-1001 (human pluripotent stem cell derived neuronal cell therapy), and the treatment was well tolerated; there have been no serious adverse events. The patient has reported having four seizures during the first three months since...
Brand Name : NRTX-1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 21, 2022
Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : ClearPoint Neuro
Deal Size : Not Applicable
Deal Type : Not Applicable
ClearPoint Neuro Congratulates Neurona Therapeutics on Dosing of Initial Subject
Details : NRTX-1001 is a regenerative neural cell therapy delivered as a single dose and designed to provide GABA, a key inhibitory neurotransmitter, to repair hyper-excitable neural networks associated with MTLE, the most common form of focal epilepsy in adults.
Brand Name : NRTX-1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 29, 2022
Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : ClearPoint Neuro
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NRTX-1001 is a regenerative neural cell therapy delivered as a single dose and designed to provide long-term secretion of gamma-aminobutyric acid (GABA), a key inhibitory neurotransmitter, to repair hyper-excitable neural networks associated with mesial ...
Brand Name : NRTX-1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 29, 2022
Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy
Therapeutic Area : Neurology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NRTX-1001 (Human Pluripotent Stem Cell Derived Neuronal Cell Therapy) is a regenerative neural cell therapy fully-differentiated neural cells, called interneurons, secrete the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
Brand Name : NRTX-1001
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 17, 2022
Lead Product(s) : Human Pluripotent Stem Cell Derived Neuronal Cell Therapy
Therapeutic Area : Neurology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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