Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : National Institutes of Health
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The new Phase 2 clinical study, which is expected to enroll approximately 100 patients, will evaluate Bryostatin-1 in the absence of Namenda® (memantine) for a six-month period, which will include two 11-week dosing cycles.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 06, 2020
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : National Institutes of Health
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Study Phase : Phase II
Recipient : Worldwide Clinical Trials
Deal Size : Undisclosed
Deal Type : Agreement
Details : Neurotrope has entered into a services agreement with Worldwide Clinical Trials to support site recruitment and activation for the Company's ongoing Phase 2 study of bryostatin-1 in the treatment of moderately severe Alzheimer's disease.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 30, 2020
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Highest Development Status : Phase II
Recipient : Worldwide Clinical Trials
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Bryostatin-1
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : BryoLogyx Inc
Deal Size : Undisclosed
Deal Type : Agreement
Details : BryoLogyx has entered into two agreements with Neurotrope for its preclinical data package and drug product for use of bryostatin-1 in an immuno-oncology application, and to supply Neurotrope with synthetic bryostatin-1 for use in clinical trials and com...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 10, 2020
Lead Product(s) : Bryostatin-1
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : BryoLogyx Inc
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : National Institutes of Health
Deal Size : $2.7 million
Deal Type : Collaboration
Details : The Phase 2 clinical study will be conducted in collaboration with the National Institutes of Health. The study will evaluate the long-term therapeutic effect of Bryostatin-1 in the absence of Namenda® (memantine) in patients with AD.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 28, 2020
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : National Institutes of Health
Deal Size : $2.7 million
Deal Type : Collaboration
Lead Product(s) : Avanafil
Therapeutic Area : Endocrinology
Study Phase : Approved
Recipient : Petros Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Merger
Details : Petros' cornerstone product would be Metuchen's Stendra® for erectile dysfunction. Petros' pipeline would include Metuchen's recently in-licensed product H-100 for Peyronie's disease, and it would include a business development program exploring variou...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 18, 2020
Lead Product(s) : Avanafil
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Recipient : Petros Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Analysis to adjust for significant baseline imbalance in severe impairment battery scores between treatment groups shows improvement in cognitive function.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 22, 2020
Lead Product(s) : Bryostatin-1
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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