Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nevakar Injectables Announces FDA Approval of Cyclophosphamide RTD Solution
Details : FDA has approved its new drug application for Cyclophosphamide Injection, 200mg/mL vials for use in combination therapy for various types of cancers, including malignant lymphoma, multiple myeloma, and various types of leukemia.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 03, 2023
Lead Product(s) : Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Recipient : Vyluma
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NVK002 (atropine) is an investigational, preservative-free, low-dose atropine eye drop, using Vyluma’s proprietary technology to address stability, tolerability, and safety and developed for the treatment of Pediatric Myopia.
Brand Name : NVK002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 06, 2023
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Recipient : Vyluma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Norepinephrine Bitartrate
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved
Sponsor : Long Grove Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Long Grove Pharmaceuticals Secures Commercial Rights to an Essential Critical Care Medication
Details : Under the agreement, Long Grove Pharmaceuticals in-licensed Norepinephrine Bitartrate in 0.9% Sodium Chloride premix formulation, indicated to raise blood pressure in adult patients with severe, acute hypotension, from Nevakar Injectables.
Brand Name : NVK004
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 04, 2023
Lead Product(s) : Norepinephrine Bitartrate
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved
Sponsor : Long Grove Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Recipient : Vyluma
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NVK002 (atropine) is a proprietary, investigational, preservative-free eye drop administered nightly, which, if approved, would be the first-in-class pharmaceutical treatment for myopia progression in children.
Brand Name : NVK002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 01, 2022
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Recipient : Vyluma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gabapentin,Pregabalin,Paracetamol
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Endo International
Deal Size : $35.0 million
Deal Type : Acquisition
Endo Acquires Six Development-Stage, Ready-to-Use Injectable Product Candidates From Nevakar
Details : With the acquisition, Endo controls all remaining development, approval, launch and commercialization activities for the product candidates, NVK009 (Gabapentin). Endo's Par Sterile Products business will commercialize the products in the United States.
Brand Name : NVK009
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 02, 2022
Lead Product(s) : Gabapentin,Pregabalin,Paracetamol
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Endo International
Deal Size : $35.0 million
Deal Type : Acquisition
Lead Product(s) : Ephedrine Sulfate
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved
Sponsor : Par Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Ephedrine Sulfate Injection (“Ephedrine”) in a prefilled syringe is a widely used injectable vasopressor agent indicated for the treatment of clinically important hypotension occurring during surgery.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 28, 2022
Lead Product(s) : Ephedrine Sulfate
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved
Sponsor : Par Pharmaceutical
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ephedrine Sulfate
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Approved
Sponsor : Endo International
Deal Size : Not Applicable
Deal Type : Not Applicable
Nevakar Injectables Announces the Launch of Ready-to-Use Ephedrine Injection Vials
Details : Ephedrine is a widely used injectable vasopressor agent indicated for the treatment of clinically important hypotension occurring during surgery, Ephedrine sulfate injection, a formulation pre-diluted to a 5mg/mL concentration and supplied in a 10mL vial...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 28, 2022
Lead Product(s) : Ephedrine Sulfate
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Approved
Sponsor : Endo International
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Oxford Finance LLC
Deal Size : Undisclosed
Deal Type : Financing
Details : The financing will support the Phase III clinical study for NVK002, Vyluma’s first-in-class pharmaceutical treatment for slowing the progression of myopia in children.
Brand Name : NVK002
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 09, 2022
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Oxford Finance LLC
Deal Size : Undisclosed
Deal Type : Financing
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Sponsor : Laboratoires Thea
Deal Size : $135.0 million
Deal Type : Collaboration
Nevakar and Théa Enter into Licensing Agreement for the Commercialization of NVK-002 in Europe
Details : Under the terms of the agreement, Nevakar will develop and obtain European Medicines Agency (“EMA”) approval for NVK-002, and Théa will launch, distribute, and support the product in Europe, as well as in parts of North Africa.
Brand Name : NVK-002
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 28, 2021
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Sponsor : Laboratoires Thea
Deal Size : $135.0 million
Deal Type : Collaboration
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Study Phase : Phase III
Recipient : Zhaoke
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The CHAMP Study is an FDA drug trial that evaluates the ability of its lead compound, NVK-002, to slow the progression of myopia in children. NVK-002 is a proprietary, investigational, preservative-free eye drop administered nightly and intended for pati...
Brand Name : NVK-002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 12, 2020
Lead Product(s) : Atropine
Therapeutic Area : Ophthalmology
Highest Development Status : Phase III
Recipient : Zhaoke
Deal Size : Not Applicable
Deal Type : Not Applicable
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