Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Newron Reports Efficacy Data from Evenamide Study in Poorly Responding Schizophrenia
Details : NW-3509 (evenamide), an orally new chemical entity, specifically blocks voltage-gated sodium channels (VGSCs), is being developed for the treatment of patients with chronic schizophrenia.
Brand Name : NW-3509
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 13, 2024
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Newron Announces Positive Results From Pivotal Phase 2/3 With Evenamide In Schizophrenia
Details : NW-3509 (evenamide), an orally available new chemical entity, specifically blocks voltage-gated sodium channels (VGSCs), is being developed for the treatment of patients with chronic schizophrenia.
Brand Name : NW-3509
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 30, 2024
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Newron Reports One-Year Results for Evenamide in Treatment-Resistant Schizophrenia
Details : NW3509 (evenamide) is an oral medication in phase 2 for treatment-resistant schizophrenia, specifically blocking sodium channels with minimal off-target effects.
Brand Name : NW3509
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 04, 2024
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NW3509 (evenamide) is an orally available new chemical entity, specifically blocks voltage-gated sodium channels (VGSCs) and is devoid of biological activity at >130 other CNS targets. It is under phase 2 clinical development for the treatment of Schizop...
Brand Name : NW3509
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 29, 2023
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NW-3509 (evenamide) is an orally available new chemical entity, specifically blocks voltage-gated sodium channels. It normalizes glutamate release induced by aberrant sodium channel activity (veratridine-stimulated), without affecting basal glutamate lev...
Brand Name : NW-3509
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 20, 2023
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Safinamide Mesylate
Therapeutic Area : Neurology
Study Phase : Phase III
Sponsor : Zambon Group SpA
Deal Size : Undisclosed
Deal Type : Agreement
Plans scrapped for Xadago Trial for Levodopa-induced Dyskinesia
Details : Under the agreement, Newron and Zambon have ended their plans to run a clinical trial to test Xadago (safinamide) for uncontrolled movements induced by levodopa in people with Parkinson’s disease.
Brand Name : Xadago
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 15, 2023
Lead Product(s) : Safinamide Mesylate
Therapeutic Area : Neurology
Highest Development Status : Phase III
Sponsor : Zambon Group SpA
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NW-3509 (evenamide), an orally available new chemical entity, specifically blocks voltage-gated sodium channels (VGSCs). It normalizes glutamate release induced by aberrant sodium channel activity (veratridine-stimulated), without affecting basal glutama...
Brand Name : NW-3509
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 16, 2023
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NW-3509 (Evenamide), an orally available new chemical entity, specifically blocks voltage-gated sodium channels (VGSCs). It normalizes glutamate release induced by aberrant sodium channel activity (veratridine-stimulated), without affecting basal glutama...
Brand Name : NW-3509
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 03, 2023
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The data presented confirm NW-3509 (evenamide) potential to improve symptoms of psychosis in patients who, despite treatment with various antipsychotics, continue to experience severe symptoms of psychosis and functional disabilities.
Brand Name : NW-3509
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 07, 2022
Lead Product(s) : Evenamide
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Safinamide Mesylate
Therapeutic Area : Neurology
Study Phase : Approved
Recipient : Zambon Switzerland
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the agreement, Newron will sponsor the study and be responsible for Xadago (safinamide), development and execution, as well as leading on all related regulatory interactions. Newron and Zambon will evenly share the cost of the study.
Brand Name : Xadago
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 12, 2021
Lead Product(s) : Safinamide Mesylate
Therapeutic Area : Neurology
Highest Development Status : Approved
Recipient : Zambon Switzerland
Deal Size : Undisclosed
Deal Type : Agreement
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