Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : NXC-201
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : CIRM
Deal Size : $8.0 million
Deal Type : Funding
California Institute Awards Funding for CAR-T NXC-201 U.S. AL Amyloidosis Trial
Details : The proceeds will support clinical development of company's chimeric antigen receptor T cell (CAR-T) therapy NXC-201 for the treatment of relapsed/refractory AL Amyloidosis.
Brand Name : NXC-201
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
July 25, 2024
Lead Product(s) : NXC-201
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : CIRM
Deal Size : $8.0 million
Deal Type : Funding
Lead Product(s) : NXC-201
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nexcella, an Immix Biopharma Subsidiary, on Track to Dose NXC-201 Patients in US
Details : NXC-201 (formerly HBI0101) CAR-T involves autologous T cells transduced ex-vivo with anti-BCMA CAR retroviral vector, being evaluated for treating relapsed/refractory AL Amyloidosis.
Brand Name : HBI0101
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
April 18, 2024
Lead Product(s) : NXC-201
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NXC-201,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nexcella Announces FDA Approval of IND Application for CAR-T NXC-201, Enabling U.S. Patient Dosing
Details : NXC-201 (formerly HBI0101) is an IND approved, BCMA-targeted investigational CAR-T cell therapy that is being studied in patients with relapsed/refractory AL amyloidosis.
Brand Name : NXC-201
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 21, 2023
Lead Product(s) : NXC-201,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NXC-201
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NXC-201, a next generation CAR-T cell therapy, is currently being evaluated in a Phase 1b/2a clinical trial for the treatment of Amyloid Light Chain (AL) Amyloidosis and received orphan drug designation from FDA.
Brand Name : NXC-201
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 21, 2023
Lead Product(s) : NXC-201
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NXC-201
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Immix Biopharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NXC-201, a next generation CAR-T cell therapy, is currently being evaluated in a Phase 1b/2a clinical trial for the treatment of Multiple Myeloma and received orphan drug designation from FDA.
Brand Name : NXC-201
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
August 23, 2023
Lead Product(s) : NXC-201
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Immix Biopharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NXC-201
Therapeutic Area : Genetic Disease
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nexcella Completes Pre-IND Meeting with FDA on NXC-201 US Clinical Trial
Details : NXC-201 (formerly HBI0101) is a BCMA-targeted investigational chimeric antigen receptor T (CAR-T) cell therapy that is being studied in a comprehensive clinical development program for the treatment of patients with relapsed or refractory multiple myelom...
Brand Name : NXC-201
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 26, 2023
Lead Product(s) : NXC-201
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NXC-201
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NXC-201 (formerly HBI0101) is a BCMA-targeted investigational chimeric antigen receptor T (CAR-T) cell therapy that is being studied in a comprehensive clinical development program for the treatment of patients with relapsed or refractory multiple myelom...
Brand Name : NXC-201
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
March 23, 2023
Lead Product(s) : NXC-201
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NXC-201
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NXC-201 (formerly HBI0101) is a BCMA-targeted investigational chimeric antigen receptor T (CAR-T) cell therapy that is being studied in a comprehensive clinical development program for the treatment of patients with relapsed or refractory multiple myelom...
Brand Name : NXC-201
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
February 27, 2023
Lead Product(s) : NXC-201
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NXC-201
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Undisclosed
Deal Type : Agreement
Details : Nexcella, Inc. initiates process of bringing NXC-201 to the United States by entering into an agreement with a well-known GMP cell therapy manufacturer that will supply Phase 1b/2 NXC-201 clinical trial material.
Brand Name : NXC-201
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
February 15, 2023
Lead Product(s) : NXC-201
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Undisclosed
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : NXC-201
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NXC-201 is a BCMA-targeted investigational chimeric antigen receptor T (CAR-T) cell therapy that is being studied in a comprehensive clinical development program for the treatment of patients with relapsed or refractory multiple myeloma and AL amyloidosi...
Brand Name : NXC-201
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
February 09, 2023
Lead Product(s) : NXC-201
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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