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Find Clinical Drug Pipeline Developments & Deals for NGM120

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pittcon 2025
                          Not Confirmed
                          Pittcon 2025
                          Not Confirmed

                          Details : NGM120 is a GFRAL antagonist designed to block GDF15 activity. It is being evaluated for the treatment of hyperemesis gravidarum in pregnant patients.

                          Product Name : NGM120

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          February 24, 2025

                          Lead Product(s) : NGM120

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Pittcon 2025
                          Not Confirmed
                          Pittcon 2025
                          Not Confirmed

                          Details : These results demonstrate that treatment with NGM120 was well tolerated to date in the study with no dose-limiting toxicities and provided encouraging signals of anti-cancer activity in patients with metastatic pancreatic cancer.

                          Product Name : NGM120

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 13, 2022

                          Lead Product(s) : NGM120,Gemcitabine,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pittcon 2025
                          Not Confirmed
                          Pittcon 2025
                          Not Confirmed

                          Details : NGM120 is an antagonist antibody that binds glial cell-derived neurotrophic factor receptor alpha-like (GFRAL) and inhibits growth differentiation factor 15 (GDF15) signaling.

                          Product Name : NGM120

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 06, 2022

                          Lead Product(s) : NGM120

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pittcon 2025
                          Not Confirmed
                          Pittcon 2025
                          Not Confirmed

                          Details : NGM120 is an antagonist antibody that binds glial cell-derived neurotrophic factor receptor alpha-like (GFRAL) and inhibits growth differentiation factor 15 (GDF15) signaling.

                          Product Name : NGM120

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 15, 2022

                          Lead Product(s) : NGM120

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pittcon 2025
                          Not Confirmed
                          Pittcon 2025
                          Not Confirmed

                          Details : NGM120 is a novel antagonist antibody that binds GFRAL and inhibits GDF15 signaling used as monotherapy or in combination with gemcitabine and Nab-paclitaxel for the potential treatment of solid tumors, especially metastatic pancreatic cancer.

                          Product Name : NGM120

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          September 16, 2021

                          Lead Product(s) : NGM120,Gemcitabine,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pittcon 2025
                          Not Confirmed
                          Pittcon 2025
                          Not Confirmed

                          Details : NGM120 is an antagonistic antibody that binds glial cell-derived neurotrophic factor receptor alpha-like (GFRAL) and inhibits growth differentiation factor 15 (GDF15) signaling.

                          Product Name : NGM120

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          March 02, 2021

                          Lead Product(s) : NGM120

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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