Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Exagamglogene Autotemcel
Therapeutic Area : Hematology
Study Phase : Approved FDF
Recipient : Vertex Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement
Vertex Secures CASGEVY® Reimbursement for Sickle Cell in England
Details : The agreement aims for eligible sickle cell disease (SCD) patients to access the CRISPR/Cas9 gene-edited therapy, Casgevy (exagamglogene autotemcel).
Product Name : Casgevy
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
January 30, 2025
Lead Product(s) : Exagamglogene Autotemcel
Therapeutic Area : Hematology
Highest Development Status : Approved FDF
Recipient : Vertex Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Atidarsagene Autotemcel
Therapeutic Area : Genetic Disease
Study Phase : Approved
Recipient : Orchard Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement
Details : The agreement coincides with publication of the positive National Institute for Health and Care Excellence’s evaluation determination, which recognized the clinical impact and economic benefit of Libmeldy according to the institute’s Highly Specializ...
Product Name : Libmeldy
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
February 04, 2022
Lead Product(s) : Atidarsagene Autotemcel
Therapeutic Area : Genetic Disease
Highest Development Status : Approved
Recipient : Orchard Therapeutics
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Inclisiran,Ezetimibe
Therapeutic Area : Genetic Disease
Study Phase : Approved FDF
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Agreement follows positive NICE recommendation and commits to deliver Leqvio® (inclisiran) access via a population health management approach identifying eligible patients across England.
Product Name : Leqvio
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
September 01, 2021
Lead Product(s) : Inclisiran,Ezetimibe
Therapeutic Area : Genetic Disease
Highest Development Status : Approved FDF
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Aspirin,Avelumab,Lansoprazole
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : University of Manchester
Deal Size : Not Applicable
Deal Type : Not Applicable
Aspirin to be Trialled as Part of New Treatment for Aggressive Form of Breast Cancer
Details : Breast Cancer Now said successful results could lead to further clinical trials of aspirin and avelumab for incurable secondary triple negative breast cancer, which happens when cancer cells that started in the breast spread to other parts of the body.
Product Name : Undisclosed
Product Type : Small molecule
Upfront Cash : Not Applicable
August 18, 2021
Lead Product(s) : Aspirin,Avelumab,Lansoprazole
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : University of Manchester
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Inclisiran
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Collaboration
Novartis, NHS England team up in 'world-first' access agreement
Details : With this collaboration, Novartis aims to bring first-in-class cholesterol lowering drug via a world-first, population health model to large at risk NHS patient population with ACD.
Product Name : Leqvio
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
January 13, 2020
Lead Product(s) : Inclisiran
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Collaboration