Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
NiKang Doses First Patient in Phase 1/1b Study of NKT3447, a Selective CDK2 Inhibitor
Details : NKT3447 is an oral, selective inhibitor of CDK2 which reduces cyclin E expression. It is being evaluated for the treatment of patients with cancers driven by cyclin E amplification or overexpression.
Brand Name : NKT3447
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 15, 2024
Lead Product(s) : NKT2152,Atezolizumab,Bevacizumab
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : F. Hoffmann-La Roche
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration aims to evaluate NKT2152, a small molecule that inhibits hypoxia inducible factor 2α (HIF2α), in combination with standard-of-care Tecentriq (atezolizumab) and Avastin (bevacizumab) in first-line treatment of unresectable/advanced hep...
Brand Name : NKT2152
Molecule Type : Small molecule
Upfront Cash : Undisclosed
December 08, 2023
Lead Product(s) : NKT2152,Atezolizumab,Bevacizumab
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : F. Hoffmann-La Roche
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : NKT2152
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Hansoh Pharma
Deal Size : $218.0 million
Deal Type : Collaboration
Details : Under the terms of the agreement, Hansoh will be responsible for all the development costs for NKT2152 in Greater China and will receive the exclusive rights to develop and commercialize NKT2152 in the region.
Brand Name : NKT2152
Molecule Type : Small molecule
Upfront Cash : $15.0 million
May 03, 2022
Lead Product(s) : NKT2152
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Hansoh Pharma
Deal Size : $218.0 million
Deal Type : Collaboration
Lead Product(s) : NKT2152
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The anti-tumor effect observed in several xenograft models suggests NKT2152, a HIF2α inhibitor, may have broader activity in other solid tumors beyond ccRCC that lack a VHL gene deficiency.
Brand Name : NKT2152
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 08, 2022
Lead Product(s) : NKT2152
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NKT2152,Tivozanib
Therapeutic Area : Oncology
Study Phase : IND Enabling
Recipient : Aveo Oncology
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration with NiKang, will play an important role in the advancement of both tivozanib and NKT2152 program. Under the terms of the agreement, NiKang will sponsor the trial and AVEO will co-fund the trial. Both companies will provide its respecti...
Brand Name : NKT2152
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 05, 2022
Lead Product(s) : NKT2152,Tivozanib
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Recipient : Aveo Oncology
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Cormorant Asset Management
Deal Size : $200.0 million
Deal Type : Series C Financing
NiKang Therapeutics Announces Completion of $200 Million Series C Financing
Details : Proceeds will be used to advance the company’s lead drug candidates into the clinic, expand the pipeline and fund internal drug discovery programs.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 26, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Cormorant Asset Management
Deal Size : $200.0 million
Deal Type : Series C Financing
Lead Product(s) : NKT-1992
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Hansoh Pharma
Deal Size : $100.0 million
Deal Type : Collaboration
Details : Under the terms of the collaboration, Hansoh Pharma will be responsible for leading development and commercialization of NKT-1992 in Greater China.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 23, 2020
Lead Product(s) : NKT-1992
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Hansoh Pharma
Deal Size : $100.0 million
Deal Type : Collaboration
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