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Find Clinical Drug Pipeline Developments & Deals for Ninlaro

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                          Top Deals by Deal Size (USD bn)

                          01

                          Wistar Institute of Anatomy and Biology

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                          2024 ACI Convention
                          Not Confirmed

                          Wistar Institute of Anatomy and Biology

                          Country arrow
                          2024 ACI Convention
                          Not Confirmed

                          Details : Under the terms of the agreement, Wistar grants Active Biotech a global exclusive license to develop and commercialize tasquinimod in combination therapy, as a treatment for multiple myeloma.

                          Brand Name : ABR-215050

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          May 22, 2024

                          Lead Product(s) : Tasquinimod,Ixazomib Citrate,Lenalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Active Biotech

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          02

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : Ninlaro® (ixazomib) is the first and only oral proteasome inhibitor licensed in combination with lenalidomide and dexamethasone for adults with multiple myeloma (MM).

                          Brand Name : Ninlaro

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 19, 2023

                          Lead Product(s) : Ixazomib Citrate,Lenalidomide,Dexamethasone

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : Tasquinimod is an oral immunomodulatory and anti-angiogenic investigational treatment, that affects the tumor’s ability to grow and metastasize. Tasquinimod is developed as a new immunomodulatory treatment for multiple myeloma.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 03, 2021

                          Lead Product(s) : Tasquinimod,Ixazomib Citrate,Lenalidomide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : Ninlaro (ixazomib) is an oral proteasome inhibitor, small molecule drug candidate which is being evaluated for the treatment of patients with multiple myeloma.

                          Brand Name : Ninlaro

                          Molecule Type :

                          Upfront Cash : Not Applicable

                          September 09, 2020

                          Lead Product(s) : Ixazomib Citrate,Lenalidomide,Dexamethasone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : Positive Phase 3 Data Evaluating NINLARO as a Maintenance Therapy (TOURMALINE-MM4) Shows Significant Improvement in Progression-Free Survival in Adult Patients Not Treated with Stem Cell Transplantation.

                          Brand Name : Ninlaro

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 12, 2020

                          Lead Product(s) : Ixazomib Citrate,Lenalidomide,Dexamethasone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase IV

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : TOURMALINE-MM4, a Phase 3, randomized clinical trial evaluating the effect of single-agent oral NINLARO™ (ixazomib), an oral proteasome inhibitor used as a first-line maintenance therapy in adult patients diagnosed with multiple myeloma.

                          Brand Name : Ninlaro

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 12, 2020

                          Lead Product(s) : Ixazomib Citrate,Lenalidomide,Dexamethasone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          2024 ACI Convention
                          Not Confirmed
                          2024 ACI Convention
                          Not Confirmed

                          Details : The addition of ixazomib to lenalidomide and dexamethasone resulted in an improvement in median progression-free survival of 13.5 months; however, it did not meet the statistical significance.

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 10, 2020

                          Lead Product(s) : Ixazomib Citrate,Lenalidomide,Dexamethasone

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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