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    [{"orgOrder":0,"company":"Nkarta Therapeutics","sponsor":"Cowen","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Public Offering","leadProduct":"Cyclophosphamide","moa":"||NKG2DL","graph1":"Oncology","graph2":"Phase I","graph3":"Nkarta Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Nkarta Therapeutics \/ Cowen","highestDevelopmentStatusID":"6","companyTruncated":"Nkarta Therapeutics \/ Cowen"},{"orgOrder":0,"company":"Nkarta Therapeutics","sponsor":"Cowen","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2022","type":"Public Offering","leadProduct":"Cyclophosphamide","moa":"||NKG2DL","graph1":"Oncology","graph2":"Phase I","graph3":"Nkarta Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph 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                            01

                            Nkarta Therapeutics

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                            Lead Product(s) : NKX019

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nkarta Receives IND Clearance for Myasthenia Gravis Trial with Ntrust-2

                            Details : NKX019 is an allogeneic, CD19-directed chimeric antigen receptor NK-cell therapy, which is being evaluated in patients with myasthenia gravis.

                            Product Name : NKX019

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            December 05, 2024

                            Lead Product(s) : NKX019

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Nkarta Therapeutics

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                            Lead Product(s) : NKX019,Cyclophosphamide

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nkarta Continues Pivot to Lupus by Shelving Lymphoma Program

                            Details : NKX019 is an allogeneic CD19 directed, off-the-shelf immunotherapy candidate, which is being evaluated for the treatment of systemic lupus erythematosus.

                            Product Name : NKX019

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            November 11, 2024

                            Lead Product(s) : NKX019,Cyclophosphamide

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Nkarta Therapeutics

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                            Lead Product(s) : NKX019,Cyclophosphamide

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nkarta Announces Investigator-Sponsored Trial of NKX019 for Lupus Erythematosus

                            Details : NKX019 is an allogeneic CD19 directed, off-the-shelf immunotherapy candidate, which is being evaluated for the treatment of systemic lupus erythematosus.

                            Product Name : NKX019

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            July 24, 2024

                            Lead Product(s) : NKX019,Cyclophosphamide

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Nkarta Therapeutics

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                            Lead Product(s) : NKX019

                            Therapeutic Area : Nephrology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nkarta Initiates NKX019 Trial in Lupus Nephritis, Expands Pipeline to Autoimmune Diseases

                            Details : NKX019 is a cryopreserved, allogeneic CD19-targeting CAR NK-cell therapy, which is being developed for the treatment of patients with lupus nephritis.

                            Product Name : NKX019

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            June 27, 2024

                            Lead Product(s) : NKX019

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Nkarta Therapeutics

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                            Lead Product(s) : NKX019

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Adage Capital Partners LP

                            Deal Size : $240.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Nkarta Announces Pricing of $240 Million Underwritten Offering

                            Details : Nkarta will use proceeds to support the clinical development of NKX019, a cryopreserved CAR NK-cell therapy targeting CD19 for relapsed/refractory non-Hodgkin lymphoma.

                            Product Name : NKX019

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            March 25, 2024

                            Lead Product(s) : NKX019

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Adage Capital Partners LP

                            Deal Size : $240.0 million

                            Deal Type : Public Offering

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                            06

                            Nkarta Therapeutics

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                            Lead Product(s) : NKX019

                            Therapeutic Area : Nephrology

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nkarta Receives FDA Clearance of IND Application for NKX019 in Lupus Nephritis

                            Details : NKX019 is an allogeneic, cryopreserved, off-the-shelf immunotherapy candidate that uses natural killer (NK) cells derived from the peripheral blood of healthy adult donors, which is investigated for the treatment of Lupus Nephritis.

                            Product Name : NKX019

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            October 17, 2023

                            Lead Product(s) : NKX019

                            Therapeutic Area : Nephrology

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Nkarta Therapeutics

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                            Lead Product(s) : NKX101,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nkarta Updates Clinical Progress of CAR-NK Cell Therapy NKX101 for Patients with Relapsed or Refractory Acute ...

                            Details : NKX101 is an allogeneic, off-the-shelf cell therapy candidate comprising NK cells derived from healthy donors and engineered to target NKG2D ligands on cancer cells and is being investigated for Relapsed or Refractory Acute Myeloid Leukemia.

                            Product Name : NKX101

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            June 27, 2023

                            Lead Product(s) : NKX101,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Nkarta Therapeutics

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                            Lead Product(s) : CD70 CAR-NK Cell

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nkarta Presents New Preclinical Data from Engineered NK Cell Platform at AACR Annual Meeting 2022

                            Details : Preclinical results showed that a combined editing and engineering strategy to armor primary NK cells via co-expression of the CD70 CAR and a membrane bound form of IL-15 (mbIL-15), together with a triple knockout of CISH, CBLB and CD70 genes using the C...

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            August 04, 2022

                            Lead Product(s) : CD70 CAR-NK Cell

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Nkarta Therapeutics

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                            Lead Product(s) : CD70 CAR-NK Cell

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Nkarta to Present Preclinical Data from Engineered NK Cell Platform at the American Association for Cancer Res...

                            Details : By combining its cell expansion and cryopreservation platform with proprietary cell engineering technologies and CRISPR-based genome engineering capabilities, Nkarta is building a pipeline of future cell therapies engineered (CD 70 CAR NK Cells) for deep...

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            August 03, 2022

                            Lead Product(s) : CD70 CAR-NK Cell

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

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                            Lead Product(s) : NKX101,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Nkarta Appoints David R. Shook, MD, as Vice President, Clinical Development

                            Details : NKX101 is an allogeneic, cryopreserved, off-the-shelf cancer immunotherapy candidate that uses natural killer (NK) cells derived from the peripheral blood of healthy donors.

                            Product Name : NKX101

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            May 16, 2022

                            Lead Product(s) : NKX101,Cyclophosphamide

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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