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Applicable"},{"orgOrder":0,"company":"Nkarta Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2021","type":"Not Applicable","leadProduct":"Cyclophosphamide","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"Nkarta Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Inhalation","sponsorNew":"Nkarta Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"Nkarta Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Nkarta Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"CD 70 CAR NK Cells","moa":"","graph1":"Oncology","graph2":"Preclinical","graph3":"Nkarta Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Nkarta Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Nkarta Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Nkarta Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"CD 70 CAR NK Cells","moa":"CD19","graph1":"Oncology","graph2":"Preclinical","graph3":"Nkarta Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Nkarta Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Nkarta Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Nkarta Therapeutics","sponsor":"Not 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Find Clinical Drug Pipeline Developments & Deals by Nkarta Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : NKX019 is an allogeneic CD19 directed, off-the-shelf immunotherapy candidate, which is being evaluated for the treatment of systemic lupus erythematosus.

                          Brand Name : NKX019

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          July 24, 2024

                          Lead Product(s) : NKX019,Cyclophosphamide

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : NKX019 is a cryopreserved, allogeneic CD19-targeting CAR NK-cell therapy, which is being developed for the treatment of patients with lupus nephritis.

                          Brand Name : NKX019

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          June 27, 2024

                          Lead Product(s) : NKX019

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : Nkarta will use proceeds to support the clinical development of NKX019, a cryopreserved CAR NK-cell therapy targeting CD19 for relapsed/refractory non-Hodgkin lymphoma.

                          Brand Name : NKX019

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          March 25, 2024

                          Lead Product(s) : NKX019

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Adage Capital Partners LP

                          Deal Size : $240.0 million

                          Deal Type : Public Offering

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                          04

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : NKX019 is an allogeneic, cryopreserved, off-the-shelf immunotherapy candidate that uses natural killer (NK) cells derived from the peripheral blood of healthy adult donors, which is investigated for the treatment of Lupus Nephritis.

                          Brand Name : NKX019

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          October 17, 2023

                          Lead Product(s) : NKX019

                          Therapeutic Area : Nephrology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : NKX101 is an allogeneic, off-the-shelf cell therapy candidate comprising NK cells derived from healthy donors and engineered to target NKG2D ligands on cancer cells and is being investigated for Relapsed or Refractory Acute Myeloid Leukemia.

                          Brand Name : NKX101

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          June 27, 2023

                          Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : NKX019 is an allogeneic, cryopreserved, off-the-shelf cancer immunotherapy candidate that uses NK cells engineered to target the B-cell antigen CD19, a clinically validated target for B-cell cancer therapies.

                          Brand Name : NKX019

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 05, 2022

                          Lead Product(s) : NKX019,Fludarabine Phosphate,Cyclophosphamide

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : NKX101 is an allogeneic, cryopreserved, off-the-shelf cancer immunotherapy candidate that uses natural killer (NK) cells derived from the peripheral blood of healthy donors.

                          Brand Name : NKX101

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          May 16, 2022

                          Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : Nkarta intends to use the net proceeds from the offering to fund the continued clinical development of NKX101 and NKX019, preclinical studies for research stage programs.

                          Brand Name : NKX101

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          April 28, 2022

                          Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Cowen

                          Deal Size : $230.0 million

                          Deal Type : Public Offering

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                          09

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : Nkarta intends to use the net proceeds to fund the continued clinical development of NKX101 and NKX019, preclinical studies for research stage programs and the continued buildout of internal manufacturing capabilities, and for working capital and general...

                          Brand Name : NKX101

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          April 26, 2022

                          Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Cowen

                          Deal Size : $200.0 million

                          Deal Type : Public Offering

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                          10

                          BMWS24
                          Not Confirmed
                          BMWS24
                          Not Confirmed

                          Details : Nkarta intends to use the net proceeds from the offering to fund the continued clinical development of NKX101 and NKX019, preclinical studies for research stage programs and the continued buildout of internal manufacturing capabilities.

                          Brand Name : NKX101

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          April 25, 2022

                          Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Cowen

                          Deal Size : Undisclosed

                          Deal Type : Public Offering

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