Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : NKX019,Cyclophosphamide
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nkarta Announces Investigator-Sponsored Trial of NKX019 for Lupus Erythematosus
Details : NKX019 is an allogeneic CD19 directed, off-the-shelf immunotherapy candidate, which is being evaluated for the treatment of systemic lupus erythematosus.
Brand Name : NKX019
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
July 24, 2024
Lead Product(s) : NKX019,Cyclophosphamide
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NKX019
Therapeutic Area : Nephrology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nkarta Initiates NKX019 Trial in Lupus Nephritis, Expands Pipeline to Autoimmune Diseases
Details : NKX019 is a cryopreserved, allogeneic CD19-targeting CAR NK-cell therapy, which is being developed for the treatment of patients with lupus nephritis.
Brand Name : NKX019
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 27, 2024
Lead Product(s) : NKX019
Therapeutic Area : Nephrology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nkarta Announces Pricing of $240 Million Underwritten Offering
Details : Nkarta will use proceeds to support the clinical development of NKX019, a cryopreserved CAR NK-cell therapy targeting CD19 for relapsed/refractory non-Hodgkin lymphoma.
Brand Name : NKX019
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
March 25, 2024
Lead Product(s) : NKX019
Therapeutic Area : Nephrology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nkarta Receives FDA Clearance of IND Application for NKX019 in Lupus Nephritis
Details : NKX019 is an allogeneic, cryopreserved, off-the-shelf immunotherapy candidate that uses natural killer (NK) cells derived from the peripheral blood of healthy adult donors, which is investigated for the treatment of Lupus Nephritis.
Brand Name : NKX019
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
October 17, 2023
Lead Product(s) : NKX019
Therapeutic Area : Nephrology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NKX101 is an allogeneic, off-the-shelf cell therapy candidate comprising NK cells derived from healthy donors and engineered to target NKG2D ligands on cancer cells and is being investigated for Relapsed or Refractory Acute Myeloid Leukemia.
Brand Name : NKX101
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
June 27, 2023
Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NKX019,Fludarabine Phosphate,Cyclophosphamide
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NKX019 is an allogeneic, cryopreserved, off-the-shelf cancer immunotherapy candidate that uses NK cells engineered to target the B-cell antigen CD19, a clinically validated target for B-cell cancer therapies.
Brand Name : NKX019
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 05, 2022
Lead Product(s) : NKX019,Fludarabine Phosphate,Cyclophosphamide
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nkarta Appoints David R. Shook, MD, as Vice President, Clinical Development
Details : NKX101 is an allogeneic, cryopreserved, off-the-shelf cancer immunotherapy candidate that uses natural killer (NK) cells derived from the peripheral blood of healthy donors.
Brand Name : NKX101
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
May 16, 2022
Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Cowen
Deal Size : $230.0 million
Deal Type : Public Offering
Details : Nkarta intends to use the net proceeds from the offering to fund the continued clinical development of NKX101 and NKX019, preclinical studies for research stage programs.
Brand Name : NKX101
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
April 28, 2022
Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Cowen
Deal Size : $230.0 million
Deal Type : Public Offering
Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Cowen
Deal Size : $200.0 million
Deal Type : Public Offering
Nkarta Announces Pricing of Upsized Public Offering of Common Stock
Details : Nkarta intends to use the net proceeds to fund the continued clinical development of NKX101 and NKX019, preclinical studies for research stage programs and the continued buildout of internal manufacturing capabilities, and for working capital and general...
Brand Name : NKX101
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
April 26, 2022
Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Cowen
Deal Size : $200.0 million
Deal Type : Public Offering
Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Cowen
Deal Size : Undisclosed
Deal Type : Public Offering
Nkarta Announces Proposed Public Offering of Common Stock
Details : Nkarta intends to use the net proceeds from the offering to fund the continued clinical development of NKX101 and NKX019, preclinical studies for research stage programs and the continued buildout of internal manufacturing capabilities.
Brand Name : NKX101
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
April 25, 2022
Lead Product(s) : NKX101,Cyclophosphamide,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Cowen
Deal Size : Undisclosed
Deal Type : Public Offering
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