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IV","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Merger","leadProduct":"SNK01","moa":"","graph1":"Neurology","graph2":"Phase I\/ Phase II","graph3":"NKGen Biotech","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"NKGen Biotech \/ Graf Acquisition Corp. IV","highestDevelopmentStatusID":"7","companyTruncated":"NKGen Biotech \/ Graf Acquisition Corp. IV"},{"orgOrder":0,"company":"NKGen Biotech","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Not Applicable","leadProduct":"SNK02","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"NKGen Biotech","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"NKGen Biotech \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"NKGen Biotech \/ Not Applicable"},{"orgOrder":0,"company":"NKGen Biotech","sponsor":"Graf Acquisition Corp.","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Merger","leadProduct":"SNK01","moa":"","graph1":"Neurology","graph2":"Phase I\/ Phase II","graph3":"NKGen Biotech","amount2":0,"highestDevelopmentShortName":"Ph 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Find Clinical Drug Pipeline Developments & Deals by NKGen Biotech

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : SNK01(troculeucel) is an autologous, non-genetically modified NK cell product that has enhanced cytotoxicity and activating receptor expression, being investigated for moderate Alzheimer’s Disease.

                          Brand Name : SNK01

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          September 12, 2024

                          Lead Product(s) : Troculeucel

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : SNK01 is a first-in-kind, autologous non-genetically modified NK cell product with significant anti-tumor cytotoxicity. It is being evaluated for the treatment of Alzheimer’s disease.

                          Brand Name : SNK01

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          May 20, 2024

                          Lead Product(s) : SNK01

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : SNK01 is an autologous, non-genetically modified NK cell product that has enhanced cytotoxicity and activating receptor expression, which is being evaluated for moderate Parkinson’s Disease.

                          Brand Name : SNK01

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          April 29, 2024

                          Lead Product(s) : SNK01

                          Therapeutic Area : Neurology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : The proceeds will be used to advance NKGen's SNK01, an autologous NK cell therapy candidate, for phase 2 alzheimer’s clinical trial and the company has recently submitted IND for parkinson’s disease.

                          Brand Name : SNK01

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          April 11, 2024

                          Lead Product(s) : SNK01

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Undisclosed

                          Deal Type : Financing

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                          05

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : SNK01 is a first-in-kind, autologous non-genetically modified NK cell product with significant anti-tumor cytotoxicity. It is being evaluated for the treatment of Alzheimer’s disease.

                          Brand Name : SNK01

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          March 25, 2024

                          Lead Product(s) : SNK01

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : SNK01 is an autologous, non-genetically modified NK cell product that has enhanced cytotoxicity and activating receptor expression, which is being evaluated in phase 1/2 clinical trials for the treatment of moderate Alzheimer’s Disease.

                          Brand Name : SNK01

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 28, 2023

                          Lead Product(s) : SNK01

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : SNK01 is an autologous, non-genetically modified NK cell product that has enhanced cytotoxicity and activating receptor expression, which is being evaluated in phase 1/2 clinical trials for the treatment of moderate Alzheimer’s Disease.

                          Brand Name : SNK01

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 27, 2023

                          Lead Product(s) : SNK01

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : SNK01 is an autologous, non-genetically modified NK cell product that has enhanced cytotoxicity and activating receptor expression, which is investigated for the treatment of moderate Alzheimer’s Disease.

                          Brand Name : SNK01

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          October 24, 2023

                          Lead Product(s) : SNK01

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : SNK01 is currently in Phase 1 trial in Mexico for the treatment of advanced Alzheimer’s disease and two Phase 1/2 trials in the US for advanced refractory solid tumors as a monotherapy and in combination with other agents including checkpoint inhibitor...

                          Brand Name : SNK01

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          October 02, 2023

                          Lead Product(s) : SNK01

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Graf Acquisition Corp.

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          10

                          Duphat
                          Not Confirmed
                          Duphat
                          Not Confirmed

                          Details : SNK02, allogeneic blood-derived NK cell therapy and will be administered as an intravenous infusion, which is investigated for treatment of solid tumors.

                          Brand Name : SNK02

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          August 24, 2023

                          Lead Product(s) : SNK02

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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