Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : NMD670
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
NMD Pharma Starts Phase 2 NMD670 Study for Charcot-Marie-Tooth Disease
Details : NMD670 is a first-in-class small molecule inhibitor of ClC-1. It is being developed by NMD Pharma for the treatment of patients with charcot-marie-tooth disease.
Brand Name : NMD670
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 18, 2024
Lead Product(s) : NMD670
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NMD670
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
NMD Pharma Receives IND Clearance from FDA to Start Phase 2 Trial of NMD670 for CMT
Details : NMD670 is a first-in-class small molecule inhibitor of ClC-1. It is being developed by NMD Pharma for the treatment of patients with charcot-marie-tooth disease.
Brand Name : NMD670
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 18, 2024
Lead Product(s) : NMD670
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NMD670
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
NMD Pharma Initiates Phase 2b Trial of NMD670 in Generalized Myasthenia Gravis Patients
Details : NMD670 is a first-in-class, muscle-targeted small molecule inhibitor ClC-1 chloride ion channel. It is being evaluated for the treatment of patients with generalized myasthenia gravis.
Brand Name : NMD670
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 11, 2024
Lead Product(s) : NMD670
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NMD670
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
NMD Pharma Receives FDA IND Clearance for NMD670 in Myasthenia Gravis Phase 2b Trial
Details : NMD670 is a muscle-targeted small molecule inhibitor of the ClC-1 chloride ion channel. It is under evaluation for treating generalized myasthenia gravis in AChR or MuSK antibody-positive patients.
Brand Name : NMD670
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 22, 2024
Lead Product(s) : NMD670
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NMD670
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Novo Holdings
Deal Size : $80.0 million
Deal Type : Series B Financing
NMD Pharma Raises €75 Million (~$80 million) in a Series B Financing
Details : The proceeds will be used to complete three Phase 2 clinical studies of first-in-class ClC-1 molecule inhibitor NMD670 in myasthenia gravis, spinal muscular atrophy and Charcot-Marie-Tooth disease.
Brand Name : NMD670
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 15, 2023
Lead Product(s) : NMD670
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Novo Holdings
Deal Size : $80.0 million
Deal Type : Series B Financing
Lead Product(s) : NMD670
Therapeutic Area : Genetic Disease
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
NMD Pharma initiates Phase II trial of NMD670 in Spinal Muscular Atrophy
Details : NMD670 is a first-in-class small molecule inhibitor of the muscle-specific chloride ion channel, the ClC-1 ion channel, which is investigated for the treatmet of spinal muscular atrophy.
Brand Name : NMD670
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 26, 2023
Lead Product(s) : NMD670
Therapeutic Area : Genetic Disease
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NMD670
Therapeutic Area : Genetic Disease
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NMD670 is a first-in-class small molecule inhibitor of the muscle specific chloride ion channel, the ClC-1 ion channel. NMD Pharma has pre-clinically demonstrated that ClC-1 inhibition can enhance neuromuscular transmission and ultimately skeletal muscle...
Brand Name : NMD670
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 14, 2022
Lead Product(s) : NMD670
Therapeutic Area : Genetic Disease
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NMD670
Therapeutic Area : Immunology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NMD670, a small molecule inhibitor of skeletal muscle-specific ClC-1, Administration of single doses of NMD670 was associated with clinically significant improvements in Quantitative Myasthenia Gravis Score with up to 50% of patients meeting pre-specifie...
Brand Name : NMD670
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 11, 2022
Lead Product(s) : NMD670
Therapeutic Area : Immunology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NMD670
Therapeutic Area : Immunology
Study Phase : Phase I/ Phase II
Sponsor : Jeito Capital
Deal Size : $39.6 million
Deal Type : Financing
NMD Pharma Raises €35 Million in a New Financing
Details : Proceeds from the financing will be used to support the company as it progresses its lead candidate, NMD670, through completion of the ongoing Phase 2a proof-of-concept trial in patients with Myasthenia Gravis (MG).
Brand Name : NMD670
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 15, 2022
Lead Product(s) : NMD670
Therapeutic Area : Immunology
Highest Development Status : Phase I/ Phase II
Sponsor : Jeito Capital
Deal Size : $39.6 million
Deal Type : Financing
Lead Product(s) : NMD670
Therapeutic Area : Immunology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NMD670 is in development to treat the symptoms of MG and is also being evaluated for the treatment of other neuromuscular diseases.
Brand Name : NMD670
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 30, 2021
Lead Product(s) : NMD670
Therapeutic Area : Immunology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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