Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : NT-0796
Therapeutic Area : Immunology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
NodThera's NT-0796 Meets Primary Endpoint in Inflammation Reversal in Obese Subjects
Details : NT-0796 is an oral, brain-penetrant NLRP3 inflammasome inhibitor, being investigated on inflammation in obese participants at risk of cardiovascular disease.
Brand Name : NT-0796
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 12, 2024
Lead Product(s) : NT-0796
Therapeutic Area : Immunology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NT-0796 is a novel chemotype, designed as an orally bioavailable, brain penetrant NLRP3 inhibitor. NT-0796 has completed its Phase 1 study confirming brain penetration with excellent pharmacokinetic (PK) & pharmacodynamic (PD) profiles.
Brand Name : NT-0796
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 21, 2022
Lead Product(s) : NT-0167
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Novo Holdings
Deal Size : $55.0 million
Deal Type : Series B Financing
NodThera Announces Close of $55 Million Series B Financing
Details : Proceeds to support advancement of pipeline of small molecule NLRP3 inflammasome inhibitors, including continued progression of NT-0167 through clinical development.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 03, 2020
Lead Product(s) : NT-0167
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Novo Holdings
Deal Size : $55.0 million
Deal Type : Series B Financing
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