Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : EQT Life Sciences
Deal Size : $147.6 million
Deal Type : Series B Financing
EQT Life Sciences Extends Noema Pharma Series B to CHF 130M Total Funding
Details : The proceeds from the financing will used for the continued development of the clinical-stage assets, including its lead candidate NOE-101 (basimglurant) for treating Seizures in Tuberous Sclerosis.
Product Name : NOE-101
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
December 11, 2024
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : EQT Life Sciences
Deal Size : $147.6 million
Deal Type : Series B Financing
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : EQT Life Sciences
Deal Size : $147.0 million
Deal Type : Series B Financing
Noema Pharma Extends Series B Financing Round, Closing at CHF 130 Million ($147 Million)
Details : The financing will support the development activities for NOE-101 (basimglurant). Currently in Phase 2 trials for severe pain in trigeminal neuralgia (TN) and seizures in tuberous sclerosis complex.
Product Name : NOE-101
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
December 11, 2024
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : EQT Life Sciences
Deal Size : $147.0 million
Deal Type : Series B Financing
Lead Product(s) : Gemlapodect
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Noema Doses First Patients in Phase 2b Trial of Gemlapodect for Tourette Syndrome
Details : NOE-105(gemlapodect) is a potential first-in-class phosphodiesterase-10A (PDE10A) inhibitor in mid-stage clinical development as a dopamine modulator for Tourette syndrome.
Product Name : NOE-105
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 30, 2024
Lead Product(s) : Gemlapodect
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Gemlapodect
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Noema’s NOE-105 Phase 2a Study in Tourette Syndrome Meets All Endpoints
Details : NOE-105 (gemlapodect) is a novel and first-in-class PDE10A inhibitor currently being studied in patients with Tourette syndrome.
Product Name : NOE-105
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 17, 2024
Lead Product(s) : Gemlapodect
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Noema Pharma Completes Enrollment for Phase 2B GALENE Trial of NOE-101 for Seizures
Details : NOE-101 (basimglurant), an mGluR5 inhibitor which is being evaluated in Phase 2b clinical trials for seizures in Tuberous Sclerosis.
Product Name : NOE-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 13, 2024
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : NOE-115
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Noema Pharma Doses First Patient in Phase 2a Study of NOE-115 for Menopause Symptoms
Details : NOE-115 is a broad-spectrum monoamine modulator, small molecule drug candidate, which is being evaluated for the treatment of women with vasomotor symptoms.
Product Name : NOE-115
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 22, 2024
Lead Product(s) : NOE-115
Therapeutic Area : Obstetrics/Gynecology (Women’s Health)
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Study Phase : Phase II/ Phase III
Sponsor : Forbion
Deal Size : $112.0 million
Deal Type : Series B Financing
Details : The proceeds of the Series B financing will be used to advance Noema Pharma's clinical-stage assets including its lead compound NOE-101 (basimglurant), an mGluR5 inhibitor which is being evaluated in Phase 2b clinical trials for severe pain in TN and sei...
Product Name : NOE-101
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
July 03, 2023
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Highest Development Status : Phase II/ Phase III
Sponsor : Forbion
Deal Size : $112.0 million
Deal Type : Series B Financing
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Noema Pharma Receives FDA Fast Track Designation for Basimglurant (NOE-101) in Trigeminal Neuralgia
Details : Basimglurant (NOE-101) is a highly selective, potent, and cell-penetrant negative allosteric modulator of metabotropic glutamate receptor 5 (mGluR5) for the treatment of trigeminal neuralgia (TN).
Product Name : NOE-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 18, 2022
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Gemlapodect
Therapeutic Area : Neurology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NOE-105 (gemlapodect) is an inhibitor of PDE10A, an enzyme highly expressed in medium spiny neurons of the mammalian striatum, which modulates D2 receptor signaling that are typically observed with most second-generation antipsychotics.
Product Name : NOE-105
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 27, 2022
Lead Product(s) : Gemlapodect
Therapeutic Area : Neurology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Study Phase : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : NOE-101 (basimglurant), a highly selective, potent, and cell-penetrant negative allosteric modulator of mGlu5 receptors for the management of pain associated with TN.
Product Name : NOE-101
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
June 09, 2022
Lead Product(s) : Basimglurant
Therapeutic Area : Neurology
Highest Development Status : Phase II/ Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable