Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Radioimmunoconjugate-based Therapy
Therapeutic Area : Oncology
Study Phase : Undisclosed
Recipient : Thor Medical
Deal Size : Undisclosed
Deal Type : Acquisition
Details : Through the acquisition, Nordic Nanovector gains access to highly promising new technology that enables the development and production of radionuclides for radioimmunoconjugate-based approaches to cancer treatment.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
June 06, 2023
Lead Product(s) : Radioimmunoconjugate-based Therapy
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Recipient : Thor Medical
Deal Size : Undisclosed
Deal Type : Acquisition
Lead Product(s) : Sodium Deoxycholate
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : APIM Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Nordic Nanovector and APIM Therapeutics Announce Merger Agreement
Details : ATX-101 is a first-in-class peptide targeting PCNA (Proliferating Cell Nuclear Antigen), a master regulator of cellular responses to stress and in tumour cell evasion from therapy. ATX-101 is currently being evaluated in platinum-sensitive ovarian cancer...
Brand Name : ATX-101
Molecule Type : Peptide
Upfront Cash : Undisclosed
November 09, 2022
Lead Product(s) : Sodium Deoxycholate
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : APIM Therapeutics
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : 177Lu Lilotomab Satetraxetan
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Betalutin (177Lu lilotomab satetraxetan), is a next-generation single-dose CD37-directed radioimmunotherapy (RIT) for the treatment of Hodgkin B-cell lymphoma.
Brand Name : Betalutin
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 05, 2022
Lead Product(s) : 177Lu Lilotomab Satetraxetan
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 177Lu Lilotomab Satetraxetan,Lilotomab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Betalutin® (177Lu Lilotomab Satetraxetan), showed signs of efficacy in this frail, elderly and difficult-to-treat patient population, the independent expert panel reported that the efficacy data are less promising than the data reported from the Phase 2...
Brand Name : Betalutin
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 21, 2022
Lead Product(s) : 177Lu Lilotomab Satetraxetan,Lilotomab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 177Lu Lilotomab Satetraxetan
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The primary objective of the PARADIGME trials is to determine the effectiveness of Betalutin (177Lu Lilotomab Satetraxetan), a novel single-dose radioimmunotherapy that targets CD37, an antigen found on the surface of tumour cells of Follicular Lymphoma.
Brand Name : Betalutin
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 02, 2022
Lead Product(s) : 177Lu Lilotomab Satetraxetan
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 177Lu-DOTA-NNV003,Olaparib
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Humalutin® (177Lu-DOTA-NNV003), acts by inducing potentially cytotoxic DNA breaks in the NHL cells, sensitising these cells to olaparib, which prevents repair of DNA breaks by blocking activity of DNA repair enzymes poly (ADP ribose) polymerase 1 and 2 ...
Brand Name : Humalutin
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 03, 2022
Lead Product(s) : 177Lu-DOTA-NNV003,Olaparib
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 177Lu Lilotomab Satetraxetan
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : 106 patients has been enrolled for PARADIGME, ongoing pivotal Phase 2b trial of Betalutin (177Lu lilotomab satetraxetan) for the treatment of anti-CD20 refractory follicular lymphoma.PARADIGME data to be reported in second half of 2022.
Brand Name : Betalutin
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 07, 2022
Lead Product(s) : 177Lu Lilotomab Satetraxetan
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 177Lu Lilotomab Satetraxetan
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nordic Nanovector to Present at 3rd Targeted Radiopharmaceutical Summit 2021
Details : Betalutin® (177Lu-lilotomab satetraxetan), an anti-CD37 beta-emitting radioimmuno conjugate has shown an encouraging efficacy and safety profile in 3rd line NHL patients who are refractory to anti-CD20-based treatments.
Brand Name : Betalutin
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 07, 2021
Lead Product(s) : 177Lu Lilotomab Satetraxetan
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 177Lu Lilotomab Satetraxetan
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : ICON Clinical Research
Deal Size : Not Applicable
Deal Type : Not Applicable
Nordic Nanovector Sees Significant Improvement in Patient Recruitment Rate in PARADIGME
Details : Nordic Nanovector's lead clinical-stage candidate is Betalutin®, a novel CD37-targeting radioimmunotherapy designed to advance the treatment of non-Hodgkin's lymphoma (NHL).
Brand Name : Betalutin
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 18, 2021
Lead Product(s) : 177Lu Lilotomab Satetraxetan
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : ICON Clinical Research
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : 177Lu Lilotomab Satetraxetan
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Nordic Nanovector has completed enrolment into the LYMRIT 37-05 Phase 1 clinical trial of Betalutin® (177Lu lilotomab satetraxetan) in patients with relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL) not eligible for autologous stem cell tran...
Brand Name : Betalutin
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 01, 2020
Lead Product(s) : 177Lu Lilotomab Satetraxetan
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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