Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : CLR 121225
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Cellectar
Deal Size : Undisclosed
Deal Type : Agreement
NorthStar Supplies Actinium-225 to Cellectar Biosciences for Therapeutic Use
Details : NorthStar will provide non-carrier added actinium-225 (n.c.a Ac-225) to Cellectar for use in CLR 121225, an actinium-labeled PLE, expected to enter a Phase 1 study in pancreatic cancer.
Brand Name : CLR 121225
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 21, 2024
Lead Product(s) : CLR 121225
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Cellectar
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Rosopatamab Tetraxetan-225Ac
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Convergent Therapeutics
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
NorthStar and Convergent Therapeutics Expand Collaboration on CONV01-alpha
Details : NorthStar will supply Convergent’s CONV01-alpha, a PSMA-targeted mAb, rosopatamab tetraxetan, linked to an alpha radiation emittier, Ac-225, for prostate cancer, with non-carrier added Ac-225 supply.
Brand Name : CONV 01-alpha
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 13, 2024
Lead Product(s) : Rosopatamab Tetraxetan-225Ac
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Convergent Therapeutics
Deal Size : Undisclosed
Deal Type : Expanded Collaboration
Lead Product(s) : MNPR-101
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Monopar Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Monopar and NorthStar Amend & Extend Collaboration
Details : NorthStar will provide Monopar with the powerful therapeutic radioisotope actinium-225 (Ac-225) in its lead MNPR-101, radio-immuno-therapeutic (RIT) for the treatment of advanced cancers.
Brand Name : MNPR-101
Molecule Type : Large molecule
Upfront Cash : Undisclosed
June 11, 2024
Lead Product(s) : MNPR-101
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Monopar Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : 67SAR-bisPSMA
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Clarity Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement
NorthStar Medical Enters Clinical Supply Agreement to Support Cu-67 SAR-bisPSMA Trials
Details : Under the agreement, NorthStar will be responsible for the production of 67Cu-SAR-bisPSMA drug product for Clarity’s Phase I/II and Phase III trials being developed in prostate cancer.
Brand Name : 67SAR-bisPSMA
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 10, 2024
Lead Product(s) : 67SAR-bisPSMA
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Clarity Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Ac-225-based Therapy
Therapeutic Area : Oncology
Study Phase : Undisclosed
Recipient : CuradhMTR
Deal Size : Undisclosed
Deal Type : Collaboration
NorthStar, Curadh Enter Agreement for Actinium-225-Based Radiopharmaceuticals
Details : NorthStar will use its technology and expertise to develop selected Curadh radiopharmaceutical targets for solid tumor cancer diagnosis and treatment.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 03, 2024
Lead Product(s) : Ac-225-based Therapy
Therapeutic Area : Oncology
Highest Development Status : Undisclosed
Recipient : CuradhMTR
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Actinium-225 Conjugated Therapy
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Curadh
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the terms of the agreement, NorthStar will supply its high purity, n.c.a. Ac-225 to Curadh for use in its pioneering molecularly targeted radiation (MTR) programs for the treatment of common lethal tumors.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 29, 2023
Lead Product(s) : Actinium-225 Conjugated Therapy
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Curadh
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : 67Cu-Sartate
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : Clarity Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : SARTATE is highly targeted theranostic radiopharmaceutical. It is developed for diagnosing, staging and subsequently treating cancers that express somatostatin receptor 2. SARTATE product can be used with 64Cu for imaging (64Cu SARTATE) or 67Cu for thera...
Brand Name : 67Cu-Sartate
Molecule Type : Peptide
Upfront Cash : Not Applicable
August 28, 2023
Lead Product(s) : 67Cu-Sartate
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : Clarity Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Actinium-225 Conjugated Therapy
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Bayer AG
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the terms of the agreement, NorthStar will provide Bayer with its environmentally preferred, non-carrier added Ac-225. NorthStar’s Ac-225 will be used by Bayer for several of its radiopharmaceutical programs, including Actinium-225 conjugated The...
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
July 18, 2023
Lead Product(s) : Actinium-225 Conjugated Therapy
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Bayer AG
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Actinium-225 Conjugated Therapy
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Nucleus RadioPharma
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under terms of the agreement, NorthStar will supply its high purity, non-carrier added Ac-225 to Nucleus. Nucleus will use NorthStar’s Ac-225 for their customers’ Actinium-225 conjugated therapy programs.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
June 27, 2023
Lead Product(s) : Actinium-225 Conjugated Therapy
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Nucleus RadioPharma
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Actinium-225 Conjugated Therapy
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inhibrx
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under this agreement with Inhibrx, NorthStar will support the development of a prespecified number of Inhibrx’s novel biologic products by providing the Ac-225 supply for the Actinium-225 Conjugated Therapy and access to its integrated radiopharmaceuti...
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Undisclosed
January 04, 2023
Lead Product(s) : Actinium-225 Conjugated Therapy
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inhibrx
Deal Size : Undisclosed
Deal Type : Collaboration
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