Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : NOUS-209,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Nouscom Completes Enrollment for NOUS-209 Phase 2 in MSI Colorectal Cancer
Details : NOUS-209 is an off-the-shelf cancer vaccine, which is currently being evaluated for the treatment of mismatch repair/microsatellite instable metastatic colorectal cancer.
Brand Name : NOUS-209
Molecule Type : Vaccine
Upfront Cash : Not Applicable
November 19, 2024
Lead Product(s) : NOUS-209,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NOUS-209,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Angelini Ventures
Deal Size : $82.1 million
Deal Type : Series C Financing
Angelini Ventures Invests €75.8 Million Series C Financing Round for Nouscom
Details : Net proceeds will advance Nouscom's clinical pipeline, including readouts from a Phase 2 trial for NOUS-209, an off-the-shelf cancer vaccine for dMMR/MSI metastatic colorectal cancer.
Brand Name : NOUS-209
Molecule Type : Vaccine
Upfront Cash : Undisclosed
March 21, 2024
Lead Product(s) : NOUS-209,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Angelini Ventures
Deal Size : $82.1 million
Deal Type : Series C Financing
Lead Product(s) : GAd20-209-FSP,MVA-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Andera Partners
Deal Size : $72.0 million
Deal Type : Series C Financing
Nouscom Raises €67.5 million ($72 million) in Oversubscribed Series C Financing Round
Details : The proceeds will be used to continue advancing and expanding Nouscom’s wholly owned clinical pipeline, including NOUS-209 (GAd20-209-FSP), an off-the-shelf cancer vaccine targeting 209 shared neoantigens.
Brand Name : NOUS-209
Molecule Type : Vaccine
Upfront Cash : Undisclosed
November 14, 2023
Lead Product(s) : GAd20-209-FSP,MVA-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Andera Partners
Deal Size : $72.0 million
Deal Type : Series C Financing
Lead Product(s) : GAd20-209-FSP,MVA-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : ProBioGen
Deal Size : Not Applicable
Deal Type : Not Applicable
Nouscom Reaches Clinical Phase II Using ProBioGen’s AGE1.CR.pIX® Production Platform
Details : Nous-209 is based on a heterologous prime/boost regimen composed of the Great Ape Adenovirus GAd20-209-FSP used for priming and Modified Vaccinia virus Ankara MVA-209-FSP used for boosting.
Brand Name : Nous-209
Molecule Type : Vaccine
Upfront Cash : Not Applicable
May 04, 2023
Lead Product(s) : GAd20-209-FSP,MVA-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : ProBioGen
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GAd20-209-FSP,MVA-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : MSD Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Details : NOUS-209 (GAd20-209-FSP) is an off-the-shelf cancer immunotherapy for MSI-H tumors. MSI-H tumors are characterized by a defective DNA mismatch repair system, which generates highly immunogenic neoantigens called frame shift peptides that are not present ...
Brand Name : NOUS-209
Molecule Type : Vaccine
Upfront Cash : Undisclosed
January 05, 2023
Lead Product(s) : GAd20-209-FSP,MVA-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : MSD Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : GAd-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NOUS-209 (GAd-209-FSP) is an off-the-shelf cancer immunotherapy for Microsatellite Instable High (MSI-H) tumors, generates highly immunogenic neoantigens called frame shift peptides (FSP) that are not present in healthy tissue.
Brand Name : NOUS-209
Molecule Type : Vaccine
Upfront Cash : Not Applicable
November 15, 2022
Lead Product(s) : GAd-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GAd-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : This mechanism was characterized in preclinical model of colorectal cancer and confirmed in Phase 1b trial in gastrointestinal patients with (MSI-H) tumors who saw durable clinical responses when treated with NOUS-209(GAd-209-FSP) in combination with ant...
Brand Name : NOUS-209
Molecule Type : Vaccine
Upfront Cash : Not Applicable
August 11, 2022
Lead Product(s) : GAd-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GAd-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NOUS-209 (GAd-209-FSP), is an off-the-shelf cancer vaccine targeting 209 shared neoantigens, in combination with anti-PD-1 checkpoint inhibitor pembrolizumab, for the treatment of deficiency in Mismatch Repair/Microsatellite Instable HigH unresectable or...
Brand Name : NOUS-209
Molecule Type : Vaccine
Upfront Cash : Not Applicable
June 06, 2022
Lead Product(s) : GAd-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GAd-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NOUS-209 (GAd-209-FSP) is an off-the-shelf immunotherapy for Microsatellite Instable High (MSI-H) tumors. MSI-H tumors are characterized by a defective DNA mismatch repair system, which generates highly immunogenic frame shift peptides that are not found...
Brand Name : NOUS-209
Molecule Type : Vaccine
Upfront Cash : Not Applicable
May 27, 2022
Lead Product(s) : GAd-209-FSP,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NOUS-PEV
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NOUS-PEV will be investigated in the study as a potential treatment for patients with either locally advanced 1L melanoma or 1L non-small cell lung cancer (NSCLC).
Brand Name : NOUS-PEV
Molecule Type : Vaccine
Upfront Cash : Not Applicable
March 11, 2021
Lead Product(s) : NOUS-PEV
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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