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Corporation","sponsor":"CareMed","pharmaFlowCategory":"D","therapeuticArea":"Nephrology","country":"SWITZERLAND","productType":"Other Small Molecule","year":"2025","type":"Partnership","leadProduct":"Atrasentan","moa":"Endothelin A receptor","graph1":"Nephrology","graph2":"Approved FDF","graph3":"Novartis Pharmaceuticals Corporation","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Novartis Pharmaceuticals Corporation \/ CareMed","highestDevelopmentStatusID":"15","companyTruncated":"Novartis Pharmaceuticals Corporation \/ CareMed"}]

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                            Lead Product(s) : Atrasentan

                            Therapeutic Area : Nephrology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

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                            Novartis Gets FDA Approval for Vanrafia® to Reduce Proteinuria in IgAN

                            Details : Vanrafia (atrasentan HCl) is an investigational oral endothelin A receptor antagonist (ERA), which is approved for IgAN and early-stage development for other rare kidney diseases.

                            Product Name : Vanrafia

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            April 02, 2025

                            Lead Product(s) : Atrasentan

                            Therapeutic Area : Nephrology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

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                            Lead Product(s) : 177Lu-vipivotide Tetraxetan,68Ga-PSMA-11

                            Therapeutic Area : Oncology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

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                            FDA Approves Novartis' Pluvicto for PSMA+ mCRPC Before Chemotherapy

                            Details : Pluvicto (lutetium Lu 177 vipivotide tetraxetan) is a prostate-specific membrane antigen, which is approved for the treatment of PSMA-positive metastatic castration-resistant prostate cancer.

                            Product Name : Pluvicto

                            Product Type : Radiolabelled Compounds

                            Upfront Cash : Inapplicable

                            March 28, 2025

                            Lead Product(s) : 177Lu-vipivotide Tetraxetan,68Ga-PSMA-11

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

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                            03

                            Alcon Inc

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                            German Wound Congress
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                            Alcon Inc

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Neltependocel

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase II

                            Recipient : Aurion Biotech

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            Alcon Acquires Aurion Biotech To Advance Corneal Cell Therapy

                            Details : Aurion will operate as a separate company with full support from Alcon to advance its clinical-stage allogeneic cell therapy asset, AURN001 for the treatment of Corneal Edema in adult.

                            Product Name : AURN001

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            March 26, 2025

                            Lead Product(s) : Neltependocel

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase II

                            Recipient : Aurion Biotech

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            04

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            German Wound Congress
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                            Novartis Pharmaceuticals Corporation

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Iptacopan HCl

                            Therapeutic Area : Nephrology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Novartis’ Fabhalta® FDA Approved for C3 Glomerulopathy (C3G) Treatment

                            Details : Fabhalta (iptacopan) is an oral, Factor B inhibitor of the alternative complement pathway. It is now approved by FDA for the treatment of patients withC3 glomerulopathy.

                            Product Name : Fabhalta

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            March 20, 2025

                            Lead Product(s) : Iptacopan HCl

                            Therapeutic Area : Nephrology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            German Wound Congress
                            Not Confirmed

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Onasemnogene Abeparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Novartis Phase III Data Shows Efficacy of Onasemnogene Abeparvovec in SMA

                            Details : Zolgensma (onasemnogene abeparvovec) is USFDA approved, one time gne therapy that acts as SMN1 gene stimulant. It is indicated for the treatment of spinal muscular atrophy.

                            Product Name : Zolgensma

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            March 19, 2025

                            Lead Product(s) : Onasemnogene Abeparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            German Wound Congress
                            Not Confirmed

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Iptacopan HCl

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Novartis oral Fabhalta® (iptacopan) Receives Positive CHMP Opinion

                            Details : Fabhalta (iptacopan) is an oral, Factor B inhibitor of the alternative complement pathway. It is being evaluated for the treatment of patients withC3 glomerulopathy.

                            Product Name : Fabhalta

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 28, 2025

                            Lead Product(s) : Iptacopan HCl

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Alcon Inc

                            U.S.A arrow
                            German Wound Congress
                            Not Confirmed

                            Alcon Inc

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Mono Propylene Glycol

                            Therapeutic Area : Ophthalmology

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Alcon Launches New Systane PRO Preservative-Free in The US

                            Details : Systane Pro PF (propylene glycol) is a one-of-a-kind multi-dose preservative-free triple action formula that hydrates, restores and protects all types of dry eyes.

                            Product Name : Systane Pro PF

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 24, 2025

                            Lead Product(s) : Mono Propylene Glycol

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            German Wound Congress
                            Not Confirmed

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Onasemnogene Abeparvovec

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Novartis Phase III Study of Onasemnogene Abeparvovec Meets Primary Endpoint in SMA

                            Details : Zolgensma (onasemnogene abeparvovec) is USFDA approved, one time gne therapy that acts as SMN1 gene stimulant. It is indicated for the treatment of spinal muscular atrophy.

                            Product Name : Zolgensma

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            December 30, 2024

                            Lead Product(s) : Onasemnogene Abeparvovec

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            German Wound Congress
                            Not Confirmed

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            German Wound Congress
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Iptacopan HCl

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Novartis' Fabhalta® Shows Hemoglobin Improvement in PNH Patients

                            Details : Fabhalta (iptacopan), a factor B inhibitor of the alternative complement pathway 15-17, is evaluated for the treatment of adults with paroxysmal nocturnal hemoglobinuria.

                            Product Name : Fabhalta

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 06, 2024

                            Lead Product(s) : Iptacopan HCl

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            German Wound Congress
                            Not Confirmed

                            Novartis Pharmaceuticals Corporation

                            Switzerland arrow
                            German Wound Congress
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : Iptacopan HCl

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Novartis Fabhalta Sustains Positive Phase 3 Results in C3 Glomerulopathy

                            Details : Fabhalta (iptacopan) is an oral, Factor B inhibitor of the alternative complement pathway. It is being evaluated for the treatment of patients withC3 glomerulopathy.

                            Product Name : LNP023

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 26, 2024

                            Lead Product(s) : Iptacopan HCl

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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