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                          Top Deals by Deal Size (USD bn)

                          01

                          Details : Through the agreement, Novasep will support Celladon’s plans to produce Mydicar, which is being evaluated in the mid-stage clinical trial for the treatment of heart failure.

                          Brand Name : Mydicar

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          December 13, 2023

                          Lead Product(s) : AAV1-based Therapy

                          Therapeutic Area : Cardiology/Vascular Diseases

                          Highest Development Status : Phase II

                          Sponsor : Celladon

                          Deal Size : $5.4 million

                          Deal Type : Agreement

                          Axplora Novasep

                          02

                          Details : Through the agreement, Novosep will perform the process development of the XB002 ADC. which is being evaluated in the early-stage clinical trial studies for the treatment of non-small cell lung cancer and cervical cancer.

                          Brand Name : XB002

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          July 07, 2021

                          Lead Product(s) : XB002,Nivolumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Exelixis

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Axplora Novasep

                          03

                          Details : The agreement aims for the manufacturing of adeno-associated virus (AAV) vectors, covering the gene therapy program targeting OTOF (OTOF-GT), the gene encoding the otoferlin protein and aims to restore the expression of Otoferlin.

                          Brand Name : OTOF-GT

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          March 11, 2020

                          Lead Product(s) : OTOF-GT

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Highest Development Status : Preclinical

                          Sponsor : Sensorion

                          Deal Size : Undisclosed

                          Deal Type : Agreement

                          Axplora Novasep