Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Plixorafenib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : Tempus
Deal Size : Undisclosed
Deal Type : Collaboration
Novellus and Tempus Announce Collaboration to Accelerate Clinical Trial Patient Enrollment
Details : Novellus’ BRAF program focuses on patient populations for which there are currently no FDA-approved BRAF inhibitors, including BRAF fusions and BRAF-mutated gliomas.
Brand Name : PLX-8394
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 23, 2020
Lead Product(s) : Plixorafenib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : Tempus
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Induced Mesenchymal Stem Cells
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Undisclosed
Sponsor : NoveCite
Deal Size : $56.0 million
Deal Type : Licensing Agreement
Details : NoveCite will develop and commercialize Novellus's iMSCs to treat acute respiratory conditions with a near term focus on Acute Respiratory Distress Syndrome ("ARDS") associated with COVID-19.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : $5.0 million
October 13, 2020
Lead Product(s) : Induced Mesenchymal Stem Cells
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Undisclosed
Sponsor : NoveCite
Deal Size : $56.0 million
Deal Type : Licensing Agreement
Lead Product(s) : NC-iMSCs therapy
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Undisclosed
Sponsor : Citius Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Novellus, a Cambridge, Mass-based cell engineering company, has developed patented, non-immunogenic mRNA-based induced mesenchymal stem cell (iMSC) platform.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
October 07, 2020
Lead Product(s) : NC-iMSCs therapy
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Undisclosed
Sponsor : Citius Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Plixorafenib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Pontifax
Deal Size : $57.0 million
Deal Type : Series C Financing
Novellus Closes $57M Series C Financing
Details : Proceeds will fund the clinical development of PLX-8394 for patients with BRAF fusions and glioma patients with BRAF mutations.
Brand Name : PLX-8394
Molecule Type : Small molecule
Upfront Cash : Undisclosed
September 21, 2020
Lead Product(s) : Plixorafenib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Pontifax
Deal Size : $57.0 million
Deal Type : Series C Financing
Lead Product(s) : Plixorafenib
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Recipient : Plexxikon
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Novellus Executes Exclusive Worldwide License Agreement with Plexxikon for PLX8394
Details : Under the terms of the agreement, Plexxikon grants Novellus rights to research, develop, manufacture and exclusively commercialize PLX8394 worldwide.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 03, 2020
Lead Product(s) : Plixorafenib
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : Plexxikon
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Mesenchymal stem cells
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Undisclosed
Sponsor : Citius Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Citius Signs Exclusive Option with Novellus to License Novel Stem-Cell Therapy for ARDS in COVID-19
Details : Citius signed an exclusive six-month option agreement to in-license a stem-cell therapy for acute respiratory distress syndrome from a subsidiary of Novellus.
Brand Name : Undisclosed
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
April 01, 2020
Lead Product(s) : Mesenchymal stem cells
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Undisclosed
Sponsor : Citius Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Licensing Agreement
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