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Find Clinical Drug Pipeline Developments & Deals by Novo Nordisk
Novo has acquired the Hemophilia A program and rights to 2seventy’s in vivo gene editing technology for autologous or allogeneic cell therapies of immune cells for the treatment of autoimmune disease.
KBP-5074 (ocedurenone) is a non-steroidal, mineralocorticoid receptor antagonist, was in development for patients with uncontrolled hypertension in patients with advanced chronic kidney disease.
NovoCare (semaglutide) is a GLP-1 receptor agonist indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management & treatment of obesity.
The collaboration combines Novo Nordisk’s expertise in diabetes and Biosplice’s research and development efforts focused on creating selective and potent DYRK inhibitors.
Awiqli (insulin icodec) is a once-weekly basal insulin analogue , which is being evaluated for the treatment of patients with Diabetes Mellitus, Type 2 & Type 1.
NNC0365-3769 (Mim8) is a next-generation FVIIIa mimetic bispecific antibody delivering sustained haemostasis for once-weekly or once-monthly prophylaxis for people living with haemophilia A, with and without inhibitors.
Under the collaboration, Novo will leverage Metaphore's MIMICTM platform in the discovery and development of up to two multitarget therapeutics leveraging GLP-1R and related biology for obesity management.
VENT-01 (NNC6022-0001) is a NLRP3 inhibitor, small molecule drug candidate, which is currently being evaluated for the treatment of cardiometabolic diseases like obesity, metabolic dysfunction-associated steatohepatitis (MASH), and chronic kidney disease.
The partnership aims to improve the manufacturing of Novo's medicines for serious chronic diseases, including diabetes and obesity medications by leveraging Ginkgo's synthetic biology platform from discovery through new ways of manufacturing.
Through the acquisition, Novo Nordisk expand its pipeline in cardiovascular disease by including Cardior’s lead compound CDR132L, currently in phase 2 clinical development for the treatment of heart failure.