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Molecule","year":"2023","type":"Licensing Agreement","leadProduct":"P-300","moa":"CREBBP\/EP300","graph1":"Oncology","graph2":"Phase I","graph3":"Novo Nordisk","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"Novo Nordisk \/ Pathos","highestDevelopmentStatusID":"6","companyTruncated":"Novo Nordisk \/ Pathos"},{"orgOrder":0,"company":"Novo Nordisk","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"DENMARK","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Ocedurenone","moa":"Mineralocorticoid receptor","graph1":"Nephrology","graph2":"Phase III","graph3":"Novo Nordisk","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Novo Nordisk \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Novo Nordisk \/ Inapplicable"},{"orgOrder":0,"company":"Novo Nordisk","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"DENMARK","productType":"Antibody","year":"2021","type":"Inapplicable","leadProduct":"Ziltivekimab","moa":"IL-6 receptor","graph1":"Nephrology","graph2":"Phase II","graph3":"Novo Nordisk","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Nephrology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Novo Nordisk \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Novo Nordisk \/ Inapplicable"}]

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                            01

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                            Lead Product(s) : LX9851

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Preclinical

                            Recipient : Lexicon pharmaceuticals

                            Deal Size : $1,000.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Lexicon Pharmaceuticals Announces Exclusive License Agreement with Novo Nordisk for LX9851

                            Details : Under the licensing agreement, Novo will hold the rights of LX9851. It is an orally delivered small molecule drug candidate for the treatment of obesity and associated cardiometabolic disorders.

                            Product Name : LX9851

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            March 28, 2025

                            Lead Product(s) : LX9851

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Preclinical

                            Recipient : Lexicon pharmaceuticals

                            Deal Size : $1,000.0 million

                            Deal Type : Licensing Agreement

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                            02

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                            Lead Product(s) : Cagrilintide,Semaglutide

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CagriSema Shows Superior Weight Loss in REDEFINE 2 Trial for Obesity & Diabetes

                            Details : CagriSema is a fixed-dose combination of a long-acting amylin analogue, cagrilintide and semaglutide. It is being investigated for adults with overweight or obesity.

                            Product Name : CagriSema

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            March 10, 2025

                            Lead Product(s) : Cagrilintide,Semaglutide

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

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                            Lead Product(s) : Mim8

                            Therapeutic Area : Genetic Disease

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Novo’s Bispecific for Hemophilia Aces Phase III Pediatric Trial

                            Details : NNC0365-3769 (Mim8) is a next-generation FVIIIa mimetic antibody delivering haemostasis for once-weekly or once-monthly prophylaxis for people living with haemophilia A, with and without inhibitors.

                            Product Name : NNC0365-3769

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 07, 2025

                            Lead Product(s) : Mim8

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

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                            Lead Product(s) : Semaglutide

                            Therapeutic Area : Nephrology

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            US FDA Approves Novo Nordisk's Ozempic to Cut Risk of Diabetic Kidney Disease Progression

                            Details : FDA has approved Ozempic (GLP-1 receptor agonists) to reduce the risk of kidney disease worsening, kidney failure, and death due to cardiovascular disease in adults with type 2 diabetes and CKD.

                            Product Name : Ozempic

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            January 28, 2025

                            Lead Product(s) : Semaglutide

                            Therapeutic Area : Nephrology

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

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                            Lead Product(s) : Amycretin

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Novo Nordisk Completes Phase 1b/2a Trial of Subcutaneous Amycretin for Obesity

                            Details : NN9487 (amycretin), a unimolecular GLP-1 & amylin receptor agonist intended for once weekly subcutaneous administration. It is being evaluated for the treatment of patients with overweight or obesity.

                            Product Name : NN9487

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 24, 2025

                            Lead Product(s) : Amycretin

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

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                            Lead Product(s) : Semaglutide

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Novo Nordisk: Semaglutide Achieves 20.7% Weight Loss in STEP UP Obesity Trial

                            Details : Wegovy (semaglutide) is a GLP-1 receptor agonist being investigated in new stregth in adults for chronic weight management & treatment of obesity.

                            Product Name : Wegovy

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            January 17, 2025

                            Lead Product(s) : Semaglutide

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

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                            Lead Product(s) : Concizumab

                            Therapeutic Area : Genetic Disease

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Approves Alhemo® Injection as Prophylactic Treatment for Hemophilia A or B

                            Details : Alhemo (concizumab) is the first anti-TFPI (Tissue Factor Pathway Inhibitor) approved by health canada for the treatment for people living with Hemophilia B in patients over the age of 12.

                            Product Name : Alhemo

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            December 20, 2024

                            Lead Product(s) : Concizumab

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

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                            Lead Product(s) : Cagrilintide,Semaglutide

                            Therapeutic Area : Nutrition and Weight Loss

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            CagriSema Demonstrates Superior Weight Loss in Adults with Obesity in REDEFINE 1 Trial

                            Details : CagriSema is a fixed-dose combination of a long-acting amylin analogue, cagrilintide and semaglutide. It is being investigated for adults with overweight or obesity.

                            Product Name : CagriSema

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            December 20, 2024

                            Lead Product(s) : Cagrilintide,Semaglutide

                            Therapeutic Area : Nutrition and Weight Loss

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

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                            Lead Product(s) : Semaglutide

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Novo Nordisk Snags Kidney Disease Expansion for Ozempic in Europe

                            Details : Ozempic belongs to a class of drugs known as GLP-1 receptor agonists and has the same active ingredient as Novo's Wegovy, slowed the worsening of kidney dysfunction in patients with type 2 diabetes.

                            Product Name : Ozempic

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            December 12, 2024

                            Lead Product(s) : Semaglutide

                            Therapeutic Area : Cardiology/Vascular Diseases

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

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                            Lead Product(s) : Etavopivat

                            Therapeutic Area : Hematology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            HIBISCUS Study Data Shows Etavopivat Reduces Sickle Cell Disease Crises

                            Details : FT-4202 (etavopivat) is a Pyruvate kinase isozymes R/L activator, which is being evaluated in adults and adolescents With sickle cell disease.

                            Product Name : FT-4202

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 07, 2024

                            Lead Product(s) : Etavopivat

                            Therapeutic Area : Hematology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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