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    [{"orgOrder":0,"company":"Novocure","sponsor":"Merck & Co","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Collaboration","leadProduct":"Tumor Treating Fields","moa":"Tumor growth","graph1":"Oncology","graph2":"Phase III","graph3":"Novocure","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Novocure \/ Novocure","highestDevelopmentStatusID":"10","companyTruncated":"Novocure \/ Novocure"},{"orgOrder":0,"company":"Novocure","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Sorafenib","moa":"Tyrosine protein kinase receptor RET","graph1":"Oncology","graph2":"Phase II","graph3":"Novocure","amount2":0,"highestDevelopmentShortName":"Ph 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Pharmaceuticals"},{"orgOrder":0,"company":"Novocure","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Large molecule","year":"2022","type":"Not Applicable","leadProduct":"Pembrolizumab","moa":"PD-1","graph1":"Oncology","graph2":"Phase III","graph3":"Novocure","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Novocure \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Novocure \/ Not Applicable"},{"orgOrder":0,"company":"Novocure","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Undisclosed","year":"2023","type":"Not Applicable","leadProduct":"NovoTTF-100L","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Novocure","amount2":0,"highestDevelopmentShortName":"Ph 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Inapplicable"},{"orgOrder":0,"company":"Novocure","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Cytotoxic Drug","year":"2022","type":"Inapplicable","leadProduct":"Temozolomide","moa":"||DNA","graph1":"Oncology","graph2":"Phase III","graph3":"Novocure","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Novocure \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"Novocure \/ Inapplicable"},{"orgOrder":0,"company":"Novocure","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Cytotoxic Drug","year":"2021","type":"Inapplicable","leadProduct":"Temozolomide","moa":"||DNA","graph1":"Oncology","graph2":"Phase III","graph3":"Novocure","amount2":0,"highestDevelopmentShortName":"Ph 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    Find Clinical Drug Pipeline Developments & Deals by Novocure

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    Lead Product(s) : Docetaxel

    Therapeutic Area : Oncology

    Study Phase : Approved FDF

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    FDA Approves Novocure’s Optune Lua® for Metastatic Lung Cancer

    Details : NovoTTF-200T, a Tumor Treating Fields (TTFields) delivery system intended for use together with docetaxel for the treatment non-small cell lung cancer in adults.

    Product Name : NovoTTF-200T

    Product Type : Cytotoxic Drug

    Upfront Cash : Inapplicable

    October 15, 2024

    Lead Product(s) : Docetaxel

    Therapeutic Area : Oncology

    Highest Development Status : Approved FDF

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Lead Product(s) : Pembrolizumab

    Therapeutic Area : Oncology

    Study Phase : Phase III

    Sponsor : Pharmakon Advisors

    Deal Size : Undisclosed

    Deal Type : Financing

    DEALS_DEV arrow-down

    Novocure Secures New $400 Million Multi-Tranche Non-Dilutive Debt Financing from Pharmakon

    Details : The proceeds will advance Novocure’s anticipated launch of NovoTTF-200T, a TTFields delivery system intended for use with pembrolizumab and platinum-based chemotherapy in non-small cell lung cancer.

    Product Name : NovoTTF-200T

    Product Type : Large molecule

    Upfront Cash : Undisclosed

    May 02, 2024

    Lead Product(s) : Pembrolizumab

    Therapeutic Area : Oncology

    Highest Development Status : Phase III

    Sponsor : Pharmakon Advisors

    Deal Size : Undisclosed

    Deal Type : Financing

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    Lead Product(s) : NovoTTF-100L,Paclitaxel

    Therapeutic Area : Oncology

    Study Phase : Phase III

    Sponsor : Not Applicable

    Deal Size : Not Applicable

    Deal Type : Not Applicable

    DEALS_DEV arrow-down

    Novocure Provides Update on Phase 3 ENGOT-ov50 / GOG-3029 / INNOVATE-3 Trial Evaluating Tumor Treating Fields ...

    Details : The phase 3 ENGOT-ov50 / GOG-3029 / INNOVATE-3 clinical trial of Tumor Treating Fields (TTFields) together with paclitaxel in patients with platinum-resistant ovarian cancer did not meet its primary endpoint of overall survival (OS) at -the final analysi...

    Product Name : NovoTTF-100L

    Product Type : Undisclosed

    Upfront Cash : Not Applicable

    August 28, 2023

    Lead Product(s) : NovoTTF-100L,Paclitaxel

    Therapeutic Area : Oncology

    Highest Development Status : Phase III

    Sponsor : Not Applicable

    Deal Size : Not Applicable

    Deal Type : Not Applicable

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    Lead Product(s) : Gemcitabine,Paclitaxel

    Therapeutic Area : Oncology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Novocure Announces Last Patient Enrolled in Pivotal PANOVA-3 Study of Tumor Treating Fields in Pancreatic Canc...

    Details : Gemcitabine (delivered via NovoTTF-200T device) is a cytotoxic agent, its metabolite dFdCDP inhibits ribonucleoside reductase (RR), an enzyme regulating DNA biosynthesis via controlling the formation of nucleoside triphosphates (NTPs). It is approved for...

    Product Name : NovoTTF-200T

    Product Type : Cytotoxic Drug

    Upfront Cash : Inapplicable

    February 15, 2023

    Lead Product(s) : Gemcitabine,Paclitaxel

    Therapeutic Area : Oncology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Lead Product(s) : Docetaxel

    Therapeutic Area : Oncology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Novocure Announces Pivotal LUNAR Study in Non-Small Cell Lung Cancer Met Primary Overall Survival Endpoint

    Details : The primary endpoint is superior overall survival of patients treated with TTFields plus immune checkpoint inhibitors or NovoTTF-200T (Docetaxel) versus immune checkpoint inhibitors or docetaxel alone.

    Product Name : NovoTTF-200T

    Product Type : Cytotoxic Drug

    Upfront Cash : Inapplicable

    January 05, 2023

    Lead Product(s) : Docetaxel

    Therapeutic Area : Oncology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Lead Product(s) : Pembrolizumab

    Therapeutic Area : Oncology

    Study Phase : Phase III

    Sponsor : Not Applicable

    Deal Size : Not Applicable

    Deal Type : Not Applicable

    DEALS_DEV arrow-down

    Novocure Enrolls First Patient in KEYNOTE-B36, a Pilot Study of Tumor Treating Fields Together with KEYTRUDA®...

    Details : KEYNOTE-B36 is designed to evaluate the safety and effectiveness of Tumor Treating Fields together with KEYTRUDA® (pembrolizumab), anti-PD-1 therapy, for the first-line treatment of locally advanced or metastatic intrathoracic non-small cell lung cancer...

    Product Name : Keytruda

    Product Type : Large molecule

    Upfront Cash : Not Applicable

    June 21, 2022

    Lead Product(s) : Pembrolizumab

    Therapeutic Area : Oncology

    Highest Development Status : Phase III

    Sponsor : Not Applicable

    Deal Size : Not Applicable

    Deal Type : Not Applicable

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    Lead Product(s) : Pembrolizumab,Temozolomide

    Therapeutic Area : Oncology

    Study Phase : Phase II

    Sponsor : MSD Pharmaceuticals

    Deal Size : Undisclosed

    Deal Type : Collaboration

    DEALS_DEV arrow-down

    Novocure Announces Clinical Collaboration with MSD on a Registrational-Intent Study to Evaluate Tumor Treating...

    Details : Novocure and MSD plan to conduct a double-blind, placebo-controlled study of TTFields concomitant with KEYTRUDA and maintenance temozolomide (TMZ) versus TTFields together with placebo and maintenance TMZ for the treatment of adult patients with newly di...

    Product Name : Keytruda

    Product Type : Large molecule

    Upfront Cash : Undisclosed

    May 26, 2022

    Lead Product(s) : Pembrolizumab,Temozolomide

    Therapeutic Area : Oncology

    Highest Development Status : Phase II

    Sponsor : MSD Pharmaceuticals

    Deal Size : Undisclosed

    Deal Type : Collaboration

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    Lead Product(s) : Gemcitabine,Paclitaxel

    Therapeutic Area : Oncology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

    DEALS_DEV arrow-down

    Novocure Announces 19 Presentations at American Association for Cancer Research (AACR) Annual Meeting 2022 Sug...

    Details : The phase III trial aimed to test the efficacy and safety of Tumor Treating Fields (TTFields) in combination with gemcitabine and nab-paclitaxel, for front line treatment of locally-advanced pancreatic adenocarcinoma.

    Product Name : Undisclosed

    Product Type : Cytotoxic Drug

    Upfront Cash : Inapplicable

    April 08, 2022

    Lead Product(s) : Gemcitabine,Paclitaxel

    Therapeutic Area : Oncology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Lead Product(s) : Temozolomide,Pembrolizumab

    Therapeutic Area : Oncology

    Study Phase : Phase II

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Updated 2-THE-TOP Data Suggest Improvements in Progression-Free Survival, Overall Survival Compared to Matched...

    Details : Patients in phase 2 pilot trial 2-THE-TOP of tumor treating fields (TTFields) together with pembrolizumab and temozolomide, showed median progression-free survival of 12.1 months compared with 7.9 months for matched-control patients from EF-14.

    Product Name : Temodar

    Product Type : Cytotoxic Drug

    Upfront Cash : Inapplicable

    March 24, 2022

    Lead Product(s) : Temozolomide,Pembrolizumab

    Therapeutic Area : Oncology

    Highest Development Status : Phase II

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Lead Product(s) : Paclitaxel

    Therapeutic Area : Oncology

    Study Phase : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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    Novocure Announces Favorable Recommendation to Continue the Phase 3 Pivotal INNOVATE-3 Study of Tumor Treating...

    Details : The primary endpoint of INNOVATE-3 is overall survival for drug-device combination of NovoTTF-100L(O) Tumor Treating Fields and Taxol (paclitaxel), The INNOVATE-3 study is designed to evaluate safety and effectiveness of TTFields together with paclitaxel...

    Product Name : Taxol

    Product Type : Cytotoxic Drug

    Upfront Cash : Inapplicable

    March 23, 2022

    Lead Product(s) : Paclitaxel

    Therapeutic Area : Oncology

    Highest Development Status : Phase III

    Sponsor : Inapplicable

    Deal Size : Inapplicable

    Deal Type : Inapplicable

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