Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : PAS-004
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Pasithea Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Pasithea Therapeutics Opens Enrollment in the U.S. for Phase 1 Trial of PAS-004
Details : PAS-004 is is a small molecule allosteric inhibitor of MEK 1/2. It is being evaluated for the treatment of neurofibromatosis type 1 and other cancer indications.
Brand Name : PAS-004
Molecule Type : Small molecule
Upfront Cash : Not Applicable
February 13, 2024
Lead Product(s) : PAS-004
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Pasithea Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : VYD222
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Recipient : Invivyd
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : VYD222 was engineered from adintrevimab (ADG20), which provided neutralizing protection against SARS-CoV-2 for all variants of concern until the emergence of the Omicron BA.2 strain and its sublineages.
Brand Name : VYD222
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 26, 2023
Lead Product(s) : VYD222
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Recipient : Invivyd
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OLP-1002
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Recipient : OliPass
Deal Size : Not Applicable
Deal Type : Not Applicable
OliPass Moves Forward to Second Stage of Phase 2a Trial for Pain Killer OLP-1002
Details : OLP-1002 is an SCN9A antisense peptide nucleic acid (PNA) and selectively inhibits the expression of Nav1.7 sodium channel, and therefore expected to replicate much of the phenotype of people with SCN9A channelopathy.
Brand Name : OLP-1002
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 18, 2022
Lead Product(s) : OLP-1002
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Recipient : OliPass
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Ifenprodil Tartrate
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Recipient : Algernon Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : In the study NP-120 (Ifenprodil), demonstrated 65% of patients had stable or improved forced vital capacity (“FVC”) over the 12-week treatment period with statistical significance when compared to an anticipated placebo effect of 40%.
Brand Name : NP-120
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 18, 2022
Lead Product(s) : Ifenprodil Tartrate
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Recipient : Algernon Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tetrahydrocannabinol
Therapeutic Area : Ophthalmology
Study Phase : Preclinical
Sponsor : Skye Bioscience
Deal Size : Undisclosed
Deal Type : Agreement
Skye Bioscience Retains Novotech as CRO for Phase 1 Trial of Glaucoma Drug Candidate
Details : SBI-100, a proprietary prodrug of tetrahydrocannabinol (“THC”), is a topical formulation under development to treat glaucoma. SBI-100 enables enhanced local delivery of the drug into the eye, reduced systemic side effects and the potential for neurop...
Brand Name : SBI-100
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 03, 2022
Lead Product(s) : Tetrahydrocannabinol
Therapeutic Area : Ophthalmology
Highest Development Status : Preclinical
Sponsor : Skye Bioscience
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Recipient : Hoth Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The first in human clinical trial is randomized, double-blind, vehicle controlled study to determine the safety, tolerability, PK and efficacy of twice daily application of topical BioLexa™ lotion, in adult and adolescent patients with mild to moderate...
Brand Name : BioLexa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 22, 2021
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Recipient : Hoth Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : XW003
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Study Phase : Phase I
Recipient : Sciwind Biosciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Sciwind's Investigational New Drug Approved for NASH Trial
Details : XW003, a potential candidate for the treatment of non-alcoholic steatohepatitis (NASH), has been approved by China NMPA for clinical trial.
Brand Name : XW003
Molecule Type : Peptide
Upfront Cash : Not Applicable
February 28, 2021
Lead Product(s) : XW003
Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)
Highest Development Status : Phase I
Recipient : Sciwind Biosciences
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GP1681
Therapeutic Area : Immunology
Study Phase : Phase I
Recipient : CytoAgents
Deal Size : Not Applicable
Deal Type : Not Applicable
CytoAgents Launches Clinical Trials for GP1681, Treatment of COVID-19 Cytokine Storm
Details : The new clinical trial is designed to evaluate the use of GP1681 as a potential new medicine to treat the severe immune response to COVID-19.
Brand Name : GP1681
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 13, 2020
Lead Product(s) : GP1681
Therapeutic Area : Immunology
Highest Development Status : Phase I
Recipient : CytoAgents
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Panaphix
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Undisclosed
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Novotech Wins Cro Contract For Komipharm Coronavirus Covid-19 Clinical Trial In South Korea
Details : The company said it seeks to expand the use of Panaphix to cover COVID-19 treatment through this proposed clinical trial.
Brand Name : Undisclosed
Molecule Type : Undisclosed
Upfront Cash : Not Applicable
March 06, 2020
Lead Product(s) : Panaphix
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Undisclosed
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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