Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : NM26
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Cormorant Asset Management
Deal Size : $197.6 million
Deal Type : Series C Financing
Numab Extends Series C to CHF 180M With CHF 50M Oversubscribed Financing
Details : The Proceeds will be used to support the advancement of multiple first-in-class and best-in-class programs into clinical development, which includes NM26-2198 is being evaluated for atopic dermatitis.
Product Name : NM26-2198
Product Type : Antibody
Upfront Cash : Undisclosed
January 09, 2025
Lead Product(s) : NM26
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Cormorant Asset Management
Deal Size : $197.6 million
Deal Type : Series C Financing
Lead Product(s) : ND081
Therapeutic Area : Gastroenterology
Study Phase : Preclinical
Sponsor : Kaken Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Numab and Kaken Collaborate On ND081 for Inflammatory Bowel Disease
Details : The collaboration aims to develop ND081, a potential first-in-class multi-specific antibody for the treatment of inflammatory bowel disease (IBD).
Product Name : ND081
Product Type : Large molecule
Upfront Cash : $14.6 million
November 15, 2024
Lead Product(s) : ND081
Therapeutic Area : Gastroenterology
Highest Development Status : Preclinical
Sponsor : Kaken Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Numab Starts Phase 1 Study of NM32 in Solid Tumor Patients
Details : NM32 is a next generation tri-specific immuno-oncology drug targeting the ROR1 receptor & CD3. It is being evaluated for the treatment of solid tumors.
Product Name : NM32
Product Type : Large molecule
Upfront Cash : Not Applicable
October 30, 2024
Lead Product(s) : NM26
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Johnson & Johnson
Deal Size : $1,250.0 million
Deal Type : Acquisition
Johnson & Johnson Gains Rights to Clinical-Stage Bispecific Antibody for Atopic Dermatitis
Details : The agreement aims to acquire NM26, a Phase 2-ready investigational, first-in-class bispecific antibody targeting two clinically proven pathways in atopic dermatitis (AD).
Product Name : NM26-2198
Product Type : Large molecule
Upfront Cash : $1,250.0 million
May 28, 2024
Lead Product(s) : NM26
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Johnson & Johnson
Deal Size : $1,250.0 million
Deal Type : Acquisition
Lead Product(s) : NM49
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Ono Pharmaceutical
Deal Size : Undisclosed
Deal Type : Collaboration
Numab and Ono Announce Collaboration Agreement for NM49 Cancer Treatment
Details : Ono obtained rights for NM49 from Numab for global development and commercialization. NM49 is a multi-specific antibody designed to activate tumor-associated macrophage phagocytosis for cancer.
Product Name : NM49
Product Type : Large molecule
Upfront Cash : Undisclosed
February 14, 2024
Lead Product(s) : NM49
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Ono Pharmaceutical
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : NM26-2198
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : NM26/NM26-2198, a first-in-class bi-specific antibody for the treatment of moderate-to-severe atopic dermatitis (AD). MAD data expected to be reported in mid-2024; Single ascending dose (SAD) cohort in healthy volunteers remains ongoing.
Product Name : NM26
Product Type : Large molecule
Upfront Cash : Not Applicable
October 19, 2023
Lead Product(s) : NM26-2198
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : NM26-2198
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Kaken Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Numab Therapeutics Announces First Subject Dosed in Phase 1 Clinical Study of NM26 Program
Details : NM26-2198 is a bi-specific antibody which targets IL-4Rα (type I and type II receptors) and IL-31 for the treatment of moderate-to-severe atopic dermatitis (AD).
Product Name : NM26-2198
Product Type : Large molecule
Upfront Cash : Not Applicable
May 15, 2023
Lead Product(s) : NM26-2198
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Kaken Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Antibody
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Ono Pharmaceutical
Deal Size : $276.6 million
Deal Type : Licensing Agreement
Details : Under the terms of the license agreement, Ono acquires intellectual property rights and exclusive global development and commercialization rights for a multispecific antibody targeting a novel immuno-oncology target.
Product Name : Undisclosed
Product Type : Large molecule
Upfront Cash : Undisclosed
March 31, 2022
Lead Product(s) : Antibody
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Ono Pharmaceutical
Deal Size : $276.6 million
Deal Type : Licensing Agreement
Lead Product(s) : ND021
Therapeutic Area : Oncology
Study Phase : Preclinical
Recipient : Sunshine Guojian Pharmaceutical
Deal Size : $15.2 million
Deal Type : Partnership
Numab and 3SBio’s Sunshine Guojian Expand Partnership to Develop Novel T Cell Engager NM28
Details : Under the agreement, Sunshine Guojian has the right to select up to five antibody molecules including ND021, emerging from the three multispecific antibody programs based on Numab’s R&D platform and has the licenses to develop and commercialize each of...
Product Name : ND021
Product Type : Large molecule
Upfront Cash : Undisclosed
December 14, 2021
Lead Product(s) : ND021
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Recipient : Sunshine Guojian Pharmaceutical
Deal Size : $15.2 million
Deal Type : Partnership
Lead Product(s) : NM21-1480
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Novo Holdings
Deal Size : $110.0 million
Deal Type : Series C Financing
Numab Therapeutics Completes Oversubscribed CHF 100 Million Series C Financing
Details : Proceeds will support acceleration and expansion of the clinical development of Numab’s lead program NM21-1480 into multiple cancer indications, and the advancement of the company’s pipeline of multi-specific antibodies in oncology and inflammation, ...
Product Name : NM21-1480
Product Type : Large molecule
Upfront Cash : Undisclosed
May 20, 2021
Lead Product(s) : NM21-1480
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Novo Holdings
Deal Size : $110.0 million
Deal Type : Series C Financing