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    Find Clinical Drug Pipeline Developments & Deals by Numab Therapeutics

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                            01

                            Numab Therapeutics

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                            Lead Product(s) : ND081

                            Therapeutic Area : Gastroenterology

                            Study Phase : Preclinical

                            Sponsor : Kaken Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Numab and Kaken Collaborate On ND081 for Inflammatory Bowel Disease

                            Details : The collaboration aims to develop ND081, a potential first-in-class multi-specific antibody for the treatment of inflammatory bowel disease (IBD).

                            Brand Name : ND081

                            Molecule Type : Large molecule

                            Upfront Cash : $14.6 million

                            November 15, 2024

                            Lead Product(s) : ND081

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Preclinical

                            Sponsor : Kaken Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            02

                            Numab Therapeutics

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                            Lead Product(s) : NM32-2668

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Numab Starts Phase 1 Study of NM32 in Solid Tumor Patients

                            Details : NM32 is a next generation tri-specific immuno-oncology drug targeting the ROR1 receptor & CD3. It is being evaluated for the treatment of solid tumors.

                            Brand Name : NM32

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 30, 2024

                            Lead Product(s) : NM32-2668

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Numab Therapeutics

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                            Lead Product(s) : NM26

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I

                            Sponsor : Johnson & Johnson

                            Deal Size : $1,250.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Johnson & Johnson Gains Rights to Clinical-Stage Bispecific Antibody for Atopic Dermatitis

                            Details : The agreement aims to acquire NM26, a Phase 2-ready investigational, first-in-class bispecific antibody targeting two clinically proven pathways in atopic dermatitis (AD).

                            Brand Name : NM26-2198

                            Molecule Type : Large molecule

                            Upfront Cash : $1,250.0 million

                            May 28, 2024

                            Lead Product(s) : NM26

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I

                            Sponsor : Johnson & Johnson

                            Deal Size : $1,250.0 million

                            Deal Type : Acquisition

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                            04

                            Numab Therapeutics

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                            Lead Product(s) : NM49

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Ono Pharmaceutical

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Numab and Ono Announce Collaboration Agreement for NM49 Cancer Treatment

                            Details : Ono obtained rights for NM49 from Numab for global development and commercialization. NM49 is a multi-specific antibody designed to activate tumor-associated macrophage phagocytosis for cancer.

                            Brand Name : NM49

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            February 14, 2024

                            Lead Product(s) : NM49

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Ono Pharmaceutical

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            05

                            Numab Therapeutics

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                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Numab Therapeutics Announces First Patient Dosed in Phase 1 Multiple Ascending Dose (MAD) Study of NM26 for Mo...

                            Details : NM26/NM26-2198, a first-in-class bi-specific antibody for the treatment of moderate-to-severe atopic dermatitis (AD). MAD data expected to be reported in mid-2024; Single ascending dose (SAD) cohort in healthy volunteers remains ongoing.

                            Brand Name : NM26

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 19, 2023

                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Study Phase : Phase I

                            Sponsor : Kaken Pharmaceuticals

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Numab Therapeutics Announces First Subject Dosed in Phase 1 Clinical Study of NM26 Program

                            Details : NM26-2198 is a bi-specific antibody which targets IL-4Rα (type I and type II receptors) and IL-31 for the treatment of moderate-to-severe atopic dermatitis (AD).

                            Brand Name : NM26-2198

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            May 15, 2023

                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Highest Development Status : Phase I

                            Sponsor : Kaken Pharmaceuticals

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Antibody

                            Therapeutic Area : Oncology

                            Study Phase : Discovery Platform

                            Sponsor : Ono Pharmaceutical

                            Deal Size : $276.6 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Numab Therapeutics and Ono Pharmaceutical Enter Development and License Agreement for Multispecific Antibody C...

                            Details : Under the terms of the license agreement, Ono acquires intellectual property rights and exclusive global development and commercialization rights for a multispecific antibody targeting a novel immuno-oncology target.

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            March 31, 2022

                            Lead Product(s) : Antibody

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery Platform

                            Sponsor : Ono Pharmaceutical

                            Deal Size : $276.6 million

                            Deal Type : Licensing Agreement

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                            08

                            Numab Therapeutics

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                            Lead Product(s) : ND021

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Sunshine Guojian Pharmaceutical

                            Deal Size : $15.2 million

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Numab and 3SBio’s Sunshine Guojian Expand Partnership to Develop Novel T Cell Engager NM28

                            Details : Under the agreement, Sunshine Guojian has the right to select up to five antibody molecules including ND021, emerging from the three multispecific antibody programs based on Numab’s R&D platform and has the licenses to develop and commercialize each of...

                            Brand Name : ND021

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            December 14, 2021

                            Lead Product(s) : ND021

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Sunshine Guojian Pharmaceutical

                            Deal Size : $15.2 million

                            Deal Type : Partnership

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                            09

                            Numab Therapeutics

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                            Lead Product(s) : NM21-1480

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Novo Holdings

                            Deal Size : $110.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            Numab Therapeutics Completes Oversubscribed CHF 100 Million Series C Financing

                            Details : Proceeds will support acceleration and expansion of the clinical development of Numab’s lead program NM21-1480 into multiple cancer indications, and the advancement of the company’s pipeline of multi-specific antibodies in oncology and inflammation, ...

                            Brand Name : NM21-1480

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            May 20, 2021

                            Lead Product(s) : NM21-1480

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Novo Holdings

                            Deal Size : $110.0 million

                            Deal Type : Series C Financing

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                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Study Phase : IND Enabling

                            Sponsor : Kaken Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Numab Therapeutics and Kaken Pharmaceutical Form Co-Development Alliance for a Next-Generation Atopic Dermatit...

                            Details : Under the expanded agreement, Kaken receives commercial rights for NM26-2198 in Japan, China, South Korea, Taiwan, Singapore, and Hong Kong, while Numab retains the commercial rights to the US, Europe, and the rest of the world.

                            Brand Name : NM26-2198

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            January 13, 2021

                            Lead Product(s) : NM26-2198

                            Therapeutic Area : Dermatology

                            Highest Development Status : IND Enabling

                            Sponsor : Kaken Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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