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                          01

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                          Details : REL-P11 is a proprietary, low-dose, modified-release psilocybin formulation, being investigated for the treatment of obesity and other metabolic diseases.

                          Brand Name : REL-P11

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 14, 2024

                          Lead Product(s) : Psilocybine

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

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                          02

                          Pharma, Lab & Chemical Expo
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                          Details : GUBamy (GUB014295) is a long-acting amylin agonist for once weekly subcutaneous administration. It is under phase 1 clinical development for the potential treatment of obesity.

                          Brand Name : GUBamy

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          November 13, 2024

                          Lead Product(s) : GUB014295

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharma, Lab & Chemical Expo
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                          Details : MD-18 is a first-in-class peptide that targets targeting protein-tyrosine phosphatase 1B (PTP1B) involved in obesity and related metabolic conditions.

                          Brand Name : MD-18

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          November 07, 2024

                          Lead Product(s) : MD-18

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : ASC47 is an adipose-targeted thyroid hormone receptor beta (THRβ) selective small molecule agonist. It is being evaluated for the treatment of obesity.

                          Brand Name : ASC47

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 07, 2024

                          Lead Product(s) : ASC47

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : CK-0045 is a long-acting analogue of interleukin-22 (IL-22), an atypical, non-immunomodulatory cytokine that selectively targets epithelial cells, is being evaluated for obesity & type 2 diabetes.

                          Brand Name : CK-0045

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 04, 2024

                          Lead Product(s) : CK-0045

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : BI 1820237 is a potent, specific peptidic NPY2R agonist in development for the treatment of overweight/obesity via once-weekly subcutaneous injection

                          Brand Name : BI 1820237

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          October 31, 2024

                          Lead Product(s) : BI 1820237,BI 456906

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase I

                          Sponsor : Boehringer Ingelheim GmbH

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Choline Chloride is an approved, intravenous phospholipid substrate replacement therapy in development for patients receiving parenteral support (PS).

                          Brand Name : Undisclosed

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 21, 2024

                          Lead Product(s) : Choline Chloride

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Lilly will receive worldwide rights to develop and commercialize Dual Amylin Calcitonin Receptor Agonists (DACRA), a new class of potential treatments for obesity and related disorders.

                          Brand Name : LY3541105

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          October 10, 2024

                          Lead Product(s) : LY3541105

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase I

                          Sponsor : Eli Lilly

                          Deal Size : $1,400.0 million

                          Deal Type : Expanded Collaboration

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                          09

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The collaboration aims to ensure supply of Metsera’s portfolio of novel injectable and oral development programs, including MET-097, a GLP-1 receptor agonists and amylin receptor agonists.

                          Brand Name : MET-097

                          Molecule Type : Peptide

                          Upfront Cash : Undisclosed

                          October 01, 2024

                          Lead Product(s) : MET-097

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase I

                          Sponsor : Metsera

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          10

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : DA-1726 is a novel, dual oxyntomodulin analog agonist that functions as a glucagon-like peptide-1 receptor (GLP1R) and glucagon receptor (GCGR), for the treatment of obesity.

                          Brand Name : DA-1726

                          Molecule Type : Peptide

                          Upfront Cash : Not Applicable

                          September 30, 2024

                          Lead Product(s) : Oxyntomodulin Analog

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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