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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Semaglutide

                          Therapeutic Area : Nutrition and Weight Loss

                          Study Phase : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Semaglutide is a GLP-1 receptor agonist, which is being investigated in Phase 3 for the treatment of weight loss type 2 diabetes and chronic kidney disease.

                          Product Name : Semaglutide-Generic

                          Product Type : Peptide

                          Upfront Cash : Not Applicable

                          October 19, 2023

                          Lead Product(s) : Semaglutide

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Dr Reddy Company Banner

                          02

                          Lead Product(s) : Semaglutide

                          Therapeutic Area : Nutrition and Weight Loss

                          Study Phase : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : subcutaneous semaglutide is a GLP-1 receptor agonist indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adults.

                          Product Name : Semaglutide-Generic

                          Product Type : Peptide

                          Upfront Cash : Not Applicable

                          October 18, 2023

                          Lead Product(s) : Semaglutide

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Dr Reddy Company Banner

                          03

                          Biotech Digital Meet
                          Not Confirmed
                          Biotech Digital Meet
                          Not Confirmed

                          Details : The proceeds from the offering will be used to advance company's lead candidate molecule, ARD-101, as well as its secondary molecule ARD-201, both of which treat hyperphagia.

                          Product Name : ARD-101

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          February 13, 2025

                          Lead Product(s) : Denatonium Acetate

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase III

                          Sponsor : Morgan Stanley

                          Deal Size : $94.2 million

                          Deal Type : Public Offering

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                          04

                          Jiangsu Hengrui Pharmaceuticals

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                          Biotech Digital Meet
                          Not Confirmed

                          Jiangsu Hengrui Pharmaceuticals

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                          Biotech Digital Meet
                          Not Confirmed

                          Details : HRS9531 is a novel injectable GLP-1/GIP receptor dual agonist formulated as an injectable peptide in clinical development for the treatment of obesity and type 2 diabetes.

                          Product Name : HRS9531

                          Product Type : Peptide

                          Upfront Cash : Inapplicable

                          January 13, 2025

                          Lead Product(s) : HRS9531

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Biotech Digital Meet
                          Not Confirmed
                          Biotech Digital Meet
                          Not Confirmed

                          Details : CagriSema is a fixed-dose combination of a long-acting amylin analogue, cagrilintide and semaglutide. It is being investigated for adults with overweight or obesity.

                          Product Name : Undisclosed

                          Product Type : Peptide

                          Upfront Cash : Not Applicable

                          December 20, 2024

                          Lead Product(s) : Cagrilintide,Semaglutide

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Biotech Digital Meet
                          Not Confirmed
                          Biotech Digital Meet
                          Not Confirmed

                          Details : The financing aims to lead the clinical development of the company's lead product HRS9531 (KAI-9531), GLP-1 receptor dual agonist formulated as an injectable peptide for the treatment of obesity.

                          Product Name : HRS9531

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          October 01, 2024

                          Lead Product(s) : KAI-9531

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase III

                          Sponsor : Atlas Venture

                          Deal Size : $400.0 million

                          Deal Type : Series A Financing

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                          07

                          Biotech Digital Meet
                          Not Confirmed
                          Biotech Digital Meet
                          Not Confirmed

                          Details : IBI362 (mazdutide) is a glucagon-like peptide-1 receptor GLP-1R/GCGR dual agonist. It is being evaluated in phase 3 clinical trials for chronic weight management.

                          Product Name : IBI362

                          Product Type : Peptide

                          Upfront Cash : Not Applicable

                          July 23, 2024

                          Lead Product(s) : Mazdutide

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase III

                          Sponsor : Eli Lilly

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Biotech Digital Meet
                          Not Confirmed
                          Biotech Digital Meet
                          Not Confirmed

                          Details : IBI362 (mazdutide) is a glucagon-like peptide-1 receptor GLP-1R/GCGR dual agonist. It is being evaluated in phase 3 clinical trials for chronic weight management.

                          Product Name : IBI362

                          Product Type : Peptide

                          Upfront Cash : Not Applicable

                          June 27, 2024

                          Lead Product(s) : Mazdutide

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Biotech Digital Meet
                          Not Confirmed
                          Biotech Digital Meet
                          Not Confirmed

                          Details : Imcivree (setmelanotide) is a MC4 receptor agonist for chronic weight management in patients 6 years and older with monogenic or syndromic obesity, under evaluation for hypothalamic obesity.

                          Product Name : Imcivree

                          Product Type : Peptide

                          Upfront Cash : Not Applicable

                          February 22, 2024

                          Lead Product(s) : Setmelanotide Acetate

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Biotech Digital Meet
                          Not Confirmed
                          Biotech Digital Meet
                          Not Confirmed

                          Details : IBI362 (mazdutide) is a glucagon-like peptide-1 receptor GLP-1R/GCGR dual agonist. It is being evaluated in phase 3 clinical trials for chronic weight management.

                          Product Name : IBI362

                          Product Type : Peptide

                          Upfront Cash : Not Applicable

                          February 07, 2024

                          Lead Product(s) : Mazdutide

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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